node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Fam189a1 | Tmem178 | ENSMUSP00000113680 | ENSMUSP00000025092 | Protein FAM189A1; Belongs to the FAM189 family. | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. | 0.576 |
Fam189a1 | Tmem179 | ENSMUSP00000113680 | ENSMUSP00000068004 | Protein FAM189A1; Belongs to the FAM189 family. | Transmembrane protein 179. | 0.709 |
Fam189a1 | Tmem88b | ENSMUSP00000113680 | ENSMUSP00000095349 | Protein FAM189A1; Belongs to the FAM189 family. | Transmembrane protein 88B. | 0.671 |
Ftsj3 | Nicn1 | ENSMUSP00000021048 | ENSMUSP00000035227 | pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3; RNA 2'-O-methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. | Nicolin-1. | 0.534 |
Ftsj3 | Tmem178 | ENSMUSP00000021048 | ENSMUSP00000025092 | pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3; RNA 2'-O-methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. | 0.512 |
Nicn1 | Ftsj3 | ENSMUSP00000035227 | ENSMUSP00000021048 | Nicolin-1. | pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3; RNA 2'-O-methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. | 0.534 |
Nicn1 | Tmem178 | ENSMUSP00000035227 | ENSMUSP00000025092 | Nicolin-1. | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. | 0.606 |
Ptchd4 | Tmem178 | ENSMUSP00000047640 | ENSMUSP00000025092 | Patched domain-containing protein 4; Could act as a repressor of canonical hedgehog signaling by antagonizing the effects of SMO, as suggested by down-regulation of hedgehog target genes, including GLI1, PTCH1, and PTCH2 in PTCHD4- expressing cells; Belongs to the patched family. | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. | 0.583 |
Tmem178 | Fam189a1 | ENSMUSP00000025092 | ENSMUSP00000113680 | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. | Protein FAM189A1; Belongs to the FAM189 family. | 0.576 |
Tmem178 | Ftsj3 | ENSMUSP00000025092 | ENSMUSP00000021048 | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. | pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3; RNA 2'-O-methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. | 0.512 |
Tmem178 | Nicn1 | ENSMUSP00000025092 | ENSMUSP00000035227 | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. | Nicolin-1. | 0.606 |
Tmem178 | Ptchd4 | ENSMUSP00000025092 | ENSMUSP00000047640 | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. | Patched domain-containing protein 4; Could act as a repressor of canonical hedgehog signaling by antagonizing the effects of SMO, as suggested by down-regulation of hedgehog target genes, including GLI1, PTCH1, and PTCH2 in PTCHD4- expressing cells; Belongs to the patched family. | 0.583 |
Tmem178 | Tmem179 | ENSMUSP00000025092 | ENSMUSP00000068004 | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. | Transmembrane protein 179. | 0.569 |
Tmem178 | Tmem47 | ENSMUSP00000025092 | ENSMUSP00000026760 | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. | Transmembrane protein 47; Regulates cell junction organization in epithelial cells. May play a role in the transition from adherens junction to tight junction assembly. May regulate F-actin polymerization required for tight junctional localization dynamics and affect the junctional localization of PARD6B. During podocyte differentiation may negatively regulate activity of FYN and subsequently the abundance of nephrin. | 0.562 |
Tmem178 | Tmem88 | ENSMUSP00000025092 | ENSMUSP00000055528 | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. | Transmembrane protein 88; Inhibits the Wnt/beta-catenin signaling pathway. Crucial for heart development and acts downstream of GATA factors in the pre- cardiac mesoderm to specify lineage commitment of cardiomyocyte development (By similarity); Belongs to the TMEM88 family. | 0.571 |
Tmem178 | Tmem88b | ENSMUSP00000025092 | ENSMUSP00000095349 | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. | Transmembrane protein 88B. | 0.554 |
Tmem178 | Tmem94 | ENSMUSP00000025092 | ENSMUSP00000091440 | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. | Transmembrane protein 94. | 0.694 |
Tmem178 | Tmem97 | ENSMUSP00000025092 | ENSMUSP00000099532 | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. | Sigma intracellular receptor 2; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins. | 0.524 |
Tmem179 | Fam189a1 | ENSMUSP00000068004 | ENSMUSP00000113680 | Transmembrane protein 179. | Protein FAM189A1; Belongs to the FAM189 family. | 0.709 |
Tmem179 | Tmem178 | ENSMUSP00000068004 | ENSMUSP00000025092 | Transmembrane protein 179. | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. | 0.569 |