STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Spata24Spermatogenesis-associated protein 24; Binds DNA with high affinity but does not bind to TATA boxes. Synergises with GMNN and TBP in activation of TATA box-containing promoters and with GMNN and TBPL1 in activation of the NF1 TATA-less promoter. May play a role in cytoplasm movement and removal during spermiogenesis; Belongs to the SPATA24 family. (205 aa)    
Predicted Functional Partners:
Zscan2
Zinc finger and SCAN domain-containing protein 2; May be involved in transcriptional regulation during the post-meiotic stages of spermatogenesis.
      
 0.653
Fam229b
Protein FAM229B; Belongs to the FAM229 family.
   
  
 0.653
4921507P07Rik
Uncharacterized protein C7orf31 homolog.
   
  
 0.651
Lrcol1
Leucine-rich colipase-like protein 1.
      
 0.649
1700066B19Rik
Small integral membrane protein 33.
      
 0.637
Spata21
Spermatogenesis-associated protein 21; Involved in the differentiation of haploid spermatids.
      
 0.631
Dnajc18
DnaJ homolog subfamily C member 18.
   
  
 0.604
Fam13b
Protein FAM13B; Belongs to the FAM13 family.
      
 0.582
Nme8
Thioredoxin domain-containing protein 3; Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. May be involved in the reduction of disulfide bonds within the sperm FS components. In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds (By similarity).
      
 0.564
1500011B03Rik
RIKEN cDNA 1500011B03 gene.
   
  
 0.521
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.