STRINGSTRING
Ppic protein (mouse) - STRING interaction network
"Ppic" - Peptidylprolyl isomerase C in Mus musculus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
PpicPeptidylprolyl isomerase C; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (212 aa)    
Predicted Functional Partners:
Crtap
Cartilage associated protein; Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues (400 aa)
     
 
  0.755
Fkbp10
FK506 binding protein 10; PPIases accelerate the folding of proteins during protein synthesis (581 aa)
     
 
  0.692
Fkbp1a
FK506 binding protein 1a; Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruites SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity) (108 aa)
     
 
  0.681
Fkbp9
FK506 binding protein 9; PPIases accelerate the folding of proteins during protein synthesis (570 aa)
     
 
  0.674
Fkbp2
FK506 binding protein 2; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (140 aa)
     
 
  0.667
Fkbp7
FK506 binding protein 7; PPIases accelerate the folding of proteins during protein synthesis (218 aa)
     
 
  0.651
Fkbp1b
FK506 binding protein 1b; Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity) (108 aa)
     
 
  0.618
Lgals3bp
Lectin, galactoside-binding, soluble, 3 binding protein; Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells (By similarity) (577 aa)
       
 
  0.612
Fkbp3
FK506 binding protein 3; FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins (By similarity) (224 aa)
     
 
  0.609
Fkbp14
FK506 binding protein 14; PPIases accelerate the folding of proteins during protein synthesis (211 aa)
     
 
  0.548
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus, Mus muscaris, Mus musculus, Mus sp. 129SV, house mouse, mice, mouse, nude mice, transgenic mice
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