node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
1700007K13Rik | Cfap161 | ENSMUSP00000083557 | ENSMUSP00000011298 | UPF0691 protein C9orf116 homolog. | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | 0.806 |
1700007K13Rik | Efcab1 | ENSMUSP00000083557 | ENSMUSP00000087744 | UPF0691 protein C9orf116 homolog. | EF-hand calcium-binding domain-containing protein 1. | 0.879 |
1700007K13Rik | Efhb | ENSMUSP00000083557 | ENSMUSP00000024725 | UPF0691 protein C9orf116 homolog. | EF-hand domain-containing family member B; Cytosolic sensor for calcium, modulates the interaction of STIM1 and ORAI1 upon store depletion, the activation of store-operated Ca(2+) entry (SOCE) and NFAT translocation from cytosol to nucleus. | 0.692 |
1700007K13Rik | Efhc1 | ENSMUSP00000083557 | ENSMUSP00000042343 | UPF0691 protein C9orf116 homolog. | EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration (By similarity). May enhance calcium influx through CACNA1E and stimulate programmed cell death. Overexpression of EFHC1 in hippocampal primary culture neurons induced apoptosis. | 0.708 |
1700007K13Rik | Efhc2 | ENSMUSP00000083557 | ENSMUSP00000026014 | UPF0691 protein C9orf116 homolog. | EF-hand domain-containing family member C2. | 0.822 |
1700007K13Rik | Pacrg | ENSMUSP00000083557 | ENSMUSP00000044376 | UPF0691 protein C9orf116 homolog. | Parkin coregulated gene protein homolog; Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited (By similarity). | 0.704 |
1700007K13Rik | Tekt1 | ENSMUSP00000083557 | ENSMUSP00000021155 | UPF0691 protein C9orf116 homolog. | Tektin-1; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity). | 0.907 |
1700007K13Rik | Tekt2 | ENSMUSP00000083557 | ENSMUSP00000099676 | UPF0691 protein C9orf116 homolog. | Tektin-2; Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Belongs to the tektin family. | 0.711 |
1700007K13Rik | Tekt4 | ENSMUSP00000083557 | ENSMUSP00000025002 | UPF0691 protein C9orf116 homolog. | Tektin-4; May be a structural component of the sperm flagellum. Contributes to normal sperm motility. | 0.764 |
1700007K13Rik | Wdr90 | ENSMUSP00000083557 | ENSMUSP00000078426 | UPF0691 protein C9orf116 homolog. | WD repeat-containing protein 90; Required for efficient primary cilium formation. | 0.589 |
Cfap161 | 1700007K13Rik | ENSMUSP00000011298 | ENSMUSP00000083557 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | UPF0691 protein C9orf116 homolog. | 0.806 |
Cfap161 | Efcab1 | ENSMUSP00000011298 | ENSMUSP00000087744 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | EF-hand calcium-binding domain-containing protein 1. | 0.494 |
Cfap161 | Efhb | ENSMUSP00000011298 | ENSMUSP00000024725 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | EF-hand domain-containing family member B; Cytosolic sensor for calcium, modulates the interaction of STIM1 and ORAI1 upon store depletion, the activation of store-operated Ca(2+) entry (SOCE) and NFAT translocation from cytosol to nucleus. | 0.564 |
Cfap161 | Efhc1 | ENSMUSP00000011298 | ENSMUSP00000042343 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration (By similarity). May enhance calcium influx through CACNA1E and stimulate programmed cell death. Overexpression of EFHC1 in hippocampal primary culture neurons induced apoptosis. | 0.669 |
Cfap161 | Efhc2 | ENSMUSP00000011298 | ENSMUSP00000026014 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | EF-hand domain-containing family member C2. | 0.813 |
Cfap161 | Pacrg | ENSMUSP00000011298 | ENSMUSP00000044376 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | Parkin coregulated gene protein homolog; Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited (By similarity). | 0.574 |
Cfap161 | Tekt1 | ENSMUSP00000011298 | ENSMUSP00000021155 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | Tektin-1; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity). | 0.668 |
Cfap161 | Tekt2 | ENSMUSP00000011298 | ENSMUSP00000099676 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | Tektin-2; Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Belongs to the tektin family. | 0.588 |
Cfap161 | Tekt4 | ENSMUSP00000011298 | ENSMUSP00000025002 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | Tektin-4; May be a structural component of the sperm flagellum. Contributes to normal sperm motility. | 0.536 |
Efcab1 | 1700007K13Rik | ENSMUSP00000087744 | ENSMUSP00000083557 | EF-hand calcium-binding domain-containing protein 1. | UPF0691 protein C9orf116 homolog. | 0.879 |