node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Gnl2 | Gtpbp4 | ENSMUSP00000030684 | ENSMUSP00000152412 | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (By similarity). | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | 0.999 |
Gnl2 | Krr1 | ENSMUSP00000030684 | ENSMUSP00000125746 | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (By similarity). | KRR1 small subunit processome component homolog; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity). | 0.654 |
Gnl2 | Mak16 | ENSMUSP00000030684 | ENSMUSP00000033983 | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (By similarity). | Protein MAK16 homolog. | 0.947 |
Gnl2 | Mrto4 | ENSMUSP00000030684 | ENSMUSP00000099561 | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (By similarity). | mRNA turnover protein 4 homolog; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. | 0.982 |
Gnl2 | Nifk | ENSMUSP00000030684 | ENSMUSP00000027626 | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (By similarity). | MKI67 FHA domain-interacting nucleolar phosphoprotein. | 0.987 |
Gnl2 | Nmd3 | ENSMUSP00000030684 | ENSMUSP00000029358 | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (By similarity). | 60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. | 0.923 |
Gnl2 | Rpf2 | ENSMUSP00000030684 | ENSMUSP00000138581 | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (By similarity). | Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus; Belongs to the RPF2 family. | 0.993 |
Gnl2 | Rrp15 | ENSMUSP00000030684 | ENSMUSP00000001339 | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (By similarity). | RRP15-like protein. | 0.829 |
Gnl2 | Rrs1 | ENSMUSP00000030684 | ENSMUSP00000071955 | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (By similarity). | Ribosome biogenesis regulatory protein homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus. | 0.970 |
Gnl2 | Tma16 | ENSMUSP00000030684 | ENSMUSP00000026681 | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (By similarity). | Translation machinery-associated protein 16. | 0.787 |
Gtpbp4 | Gnl2 | ENSMUSP00000152412 | ENSMUSP00000030684 | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (By similarity). | 0.999 |
Gtpbp4 | Krr1 | ENSMUSP00000152412 | ENSMUSP00000125746 | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | KRR1 small subunit processome component homolog; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity). | 0.750 |
Gtpbp4 | Mak16 | ENSMUSP00000152412 | ENSMUSP00000033983 | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | Protein MAK16 homolog. | 0.989 |
Gtpbp4 | Mrto4 | ENSMUSP00000152412 | ENSMUSP00000099561 | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | mRNA turnover protein 4 homolog; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. | 0.999 |
Gtpbp4 | Nifk | ENSMUSP00000152412 | ENSMUSP00000027626 | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | MKI67 FHA domain-interacting nucleolar phosphoprotein. | 0.998 |
Gtpbp4 | Nmd3 | ENSMUSP00000152412 | ENSMUSP00000029358 | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | 60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. | 0.994 |
Gtpbp4 | Rpf2 | ENSMUSP00000152412 | ENSMUSP00000138581 | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus; Belongs to the RPF2 family. | 0.998 |
Gtpbp4 | Rrp15 | ENSMUSP00000152412 | ENSMUSP00000001339 | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | RRP15-like protein. | 0.954 |
Gtpbp4 | Rrs1 | ENSMUSP00000152412 | ENSMUSP00000071955 | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | Ribosome biogenesis regulatory protein homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus. | 0.974 |
Gtpbp4 | Tma16 | ENSMUSP00000152412 | ENSMUSP00000026681 | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | Translation machinery-associated protein 16. | 0.919 |