node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Gart | Rab10 | ENSMUSP00000023684 | ENSMUSP00000021001 | Trifunctional purine biosynthetic protein adenosine-3; In the N-terminal section; belongs to the GARS family. In the C-terminal section; belongs to the GART family. | Ras-related protein Rab-10; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (By similarity). Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). That Rab is mainly involved in the biosynthetic transport of proteins from the Golgi to the plasma membrane (By similarity). Regulates, for instance, SLC [...] | 0.467 |
Gart | Slc28a1 | ENSMUSP00000023684 | ENSMUSP00000112421 | Trifunctional purine biosynthetic protein adenosine-3; In the N-terminal section; belongs to the GARS family. In the C-terminal section; belongs to the GART family. | Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. | 0.533 |
Gart | Tymp | ENSMUSP00000023684 | ENSMUSP00000023285 | Trifunctional purine biosynthetic protein adenosine-3; In the N-terminal section; belongs to the GARS family. In the C-terminal section; belongs to the GART family. | Thymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity); Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.575 |
Rab10 | Gart | ENSMUSP00000021001 | ENSMUSP00000023684 | Ras-related protein Rab-10; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (By similarity). Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). That Rab is mainly involved in the biosynthetic transport of proteins from the Golgi to the plasma membrane (By similarity). Regulates, for instance, SLC [...] | Trifunctional purine biosynthetic protein adenosine-3; In the N-terminal section; belongs to the GARS family. In the C-terminal section; belongs to the GART family. | 0.467 |
Rab10 | Slc28a1 | ENSMUSP00000021001 | ENSMUSP00000112421 | Ras-related protein Rab-10; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (By similarity). Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). That Rab is mainly involved in the biosynthetic transport of proteins from the Golgi to the plasma membrane (By similarity). Regulates, for instance, SLC [...] | Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. | 0.523 |
Slc22a4 | Slc28a1 | ENSMUSP00000020586 | ENSMUSP00000112421 | Solute carrier family 22 member 4; Sodium-ion dependent, low affinity carnitine transporter. Probably transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Relative uptake activity ratio of carnitine to TEA is 1.78; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. | Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. | 0.524 |
Slc22a4 | Slc29a1 | ENSMUSP00000020586 | ENSMUSP00000131976 | Solute carrier family 22 member 4; Sodium-ion dependent, low affinity carnitine transporter. Probably transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Relative uptake activity ratio of carnitine to TEA is 1.78; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. | Equilibrative nucleoside transporter 1; Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Resistant to dipyridamole and dilazep inhibition (anticancer chemotherapeutics drugs). | 0.475 |
Slc22a4 | Slc29a2 | ENSMUSP00000020586 | ENSMUSP00000157780 | Solute carrier family 22 member 4; Sodium-ion dependent, low affinity carnitine transporter. Probably transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Relative uptake activity ratio of carnitine to TEA is 1.78; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. | Equilibrative nucleoside transporter 2; Mediates equilibrative transport of purine and pyrimidine nucleosides, and the purine base hypoxanthine; Belongs to the SLC29A/ENT transporter (TC 2.A.57) family. | 0.452 |
Slc22a4 | Slc29a3 | ENSMUSP00000020586 | ENSMUSP00000112685 | Solute carrier family 22 member 4; Sodium-ion dependent, low affinity carnitine transporter. Probably transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Relative uptake activity ratio of carnitine to TEA is 1.78; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. | Equilibrative nucleoside transporter 3; Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). Mediates transport of adenine, adenosine and uridine (By similarity); Belongs to the SLC29A/ENT transporter (TC 2.A.57) family. | 0.400 |
Slc22a7 | Slc28a1 | ENSMUSP00000084234 | ENSMUSP00000112421 | Solute carrier family 22 member 7; Mediates sodium-independent multispecific organic anion transport. High affinity transport of glutarate and prostaglandin E2 in a sodium-independent manner. Mediates also the uptake of alpha- ketoglutarate, p-aminohippuric acid, methotrexate, ochratoxin A, valproate, allopurinol and bumetanide. | Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. | 0.551 |
Slc22a7 | Slc29a1 | ENSMUSP00000084234 | ENSMUSP00000131976 | Solute carrier family 22 member 7; Mediates sodium-independent multispecific organic anion transport. High affinity transport of glutarate and prostaglandin E2 in a sodium-independent manner. Mediates also the uptake of alpha- ketoglutarate, p-aminohippuric acid, methotrexate, ochratoxin A, valproate, allopurinol and bumetanide. | Equilibrative nucleoside transporter 1; Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Resistant to dipyridamole and dilazep inhibition (anticancer chemotherapeutics drugs). | 0.560 |
Slc22a7 | Slc29a2 | ENSMUSP00000084234 | ENSMUSP00000157780 | Solute carrier family 22 member 7; Mediates sodium-independent multispecific organic anion transport. High affinity transport of glutarate and prostaglandin E2 in a sodium-independent manner. Mediates also the uptake of alpha- ketoglutarate, p-aminohippuric acid, methotrexate, ochratoxin A, valproate, allopurinol and bumetanide. | Equilibrative nucleoside transporter 2; Mediates equilibrative transport of purine and pyrimidine nucleosides, and the purine base hypoxanthine; Belongs to the SLC29A/ENT transporter (TC 2.A.57) family. | 0.437 |
Slc28a1 | Gart | ENSMUSP00000112421 | ENSMUSP00000023684 | Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. | Trifunctional purine biosynthetic protein adenosine-3; In the N-terminal section; belongs to the GARS family. In the C-terminal section; belongs to the GART family. | 0.533 |
Slc28a1 | Rab10 | ENSMUSP00000112421 | ENSMUSP00000021001 | Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. | Ras-related protein Rab-10; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (By similarity). Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). That Rab is mainly involved in the biosynthetic transport of proteins from the Golgi to the plasma membrane (By similarity). Regulates, for instance, SLC [...] | 0.523 |
Slc28a1 | Slc22a4 | ENSMUSP00000112421 | ENSMUSP00000020586 | Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. | Solute carrier family 22 member 4; Sodium-ion dependent, low affinity carnitine transporter. Probably transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Relative uptake activity ratio of carnitine to TEA is 1.78; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. | 0.524 |
Slc28a1 | Slc22a7 | ENSMUSP00000112421 | ENSMUSP00000084234 | Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. | Solute carrier family 22 member 7; Mediates sodium-independent multispecific organic anion transport. High affinity transport of glutarate and prostaglandin E2 in a sodium-independent manner. Mediates also the uptake of alpha- ketoglutarate, p-aminohippuric acid, methotrexate, ochratoxin A, valproate, allopurinol and bumetanide. | 0.551 |
Slc28a1 | Slc29a1 | ENSMUSP00000112421 | ENSMUSP00000131976 | Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. | Equilibrative nucleoside transporter 1; Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Resistant to dipyridamole and dilazep inhibition (anticancer chemotherapeutics drugs). | 0.858 |
Slc28a1 | Slc29a2 | ENSMUSP00000112421 | ENSMUSP00000157780 | Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. | Equilibrative nucleoside transporter 2; Mediates equilibrative transport of purine and pyrimidine nucleosides, and the purine base hypoxanthine; Belongs to the SLC29A/ENT transporter (TC 2.A.57) family. | 0.859 |
Slc28a1 | Slc29a3 | ENSMUSP00000112421 | ENSMUSP00000112685 | Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. | Equilibrative nucleoside transporter 3; Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). Mediates transport of adenine, adenosine and uridine (By similarity); Belongs to the SLC29A/ENT transporter (TC 2.A.57) family. | 0.771 |
Slc28a1 | Slc29a4 | ENSMUSP00000112421 | ENSMUSP00000059896 | Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. | Equilibrative nucleoside transporter 4; Functions as a polyspecific organic cation transporter, efficiently transporting many organic cations such as monoamine neurotransmitters 1-methyl-4-phenylpyridinium and biogenic amines including serotonin, dopamine, norepinephrine and epinephrine. May play a role in regulating central nervous system homeostasis of monoamine neurotransmitters. May be involved in luminal transport of organic cations in the kidney and seems to use luminal proton gradient to drive organic cation reabsorptprev reabsorption. Does not seem to transport nucleoside and n [...] | 0.742 |