node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bcas3 | Rer1 | ENSMUSP00000074416 | ENSMUSP00000030914 | Breast carcinoma-amplified sequence 3 homolog; Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. Binds to chromatin (By similarity). Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation. Belongs to the BCAS3 family. | Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment; Belongs to the RER1 family. | 0.409 |
Bcas3 | Slc23a3 | ENSMUSP00000074416 | ENSMUSP00000027405 | Breast carcinoma-amplified sequence 3 homolog; Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. Binds to chromatin (By similarity). Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation. Belongs to the BCAS3 family. | Solute carrier family 23 member 3. | 0.468 |
Bcas3 | Snrpf | ENSMUSP00000074416 | ENSMUSP00000020203 | Breast carcinoma-amplified sequence 3 homolog; Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. Binds to chromatin (By similarity). Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation. Belongs to the BCAS3 family. | Small nuclear ribonucleoprotein F; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. | 0.413 |
Cnppd1 | Slc23a3 | ENSMUSP00000132688 | ENSMUSP00000027405 | Protein CNPPD1. | Solute carrier family 23 member 3. | 0.487 |
Cnppd1 | Xrcc4 | ENSMUSP00000132688 | ENSMUSP00000022115 | Protein CNPPD1. | DNA repair protein XRCC4; Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends (By similarity). | 0.461 |
Cnppd1 | Xrcc5 | ENSMUSP00000132688 | ENSMUSP00000027379 | Protein CNPPD1. | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic s [...] | 0.640 |
Mfsd11 | Slc23a3 | ENSMUSP00000021173 | ENSMUSP00000027405 | UNC93-like protein MFSD11. | Solute carrier family 23 member 3. | 0.448 |
Rer1 | Bcas3 | ENSMUSP00000030914 | ENSMUSP00000074416 | Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment; Belongs to the RER1 family. | Breast carcinoma-amplified sequence 3 homolog; Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. Binds to chromatin (By similarity). Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation. Belongs to the BCAS3 family. | 0.409 |
Rer1 | Slc23a3 | ENSMUSP00000030914 | ENSMUSP00000027405 | Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment; Belongs to the RER1 family. | Solute carrier family 23 member 3. | 0.440 |
Rer1 | Snrpf | ENSMUSP00000030914 | ENSMUSP00000020203 | Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment; Belongs to the RER1 family. | Small nuclear ribonucleoprotein F; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. | 0.422 |
Slc16a9 | Slc17a4 | ENSMUSP00000047912 | ENSMUSP00000021769 | Monocarboxylate transporter 9; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. | Probable small intestine urate exporter; Acts as a membrane potential-dependent organic anion transporter, the transport requires a low concentration of chloride ions. May be involved in urate extrusion from the intestinal duct. May recognize hydrophilic anionic drugs such as aspirin, salicylate, and ibuprofen as substrates. Able to actively transport inorganic phosphate into cells via Na(+) cotransport (in vitro) (By similarity). Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. | 0.681 |
Slc16a9 | Slc23a3 | ENSMUSP00000047912 | ENSMUSP00000027405 | Monocarboxylate transporter 9; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. | Solute carrier family 23 member 3. | 0.536 |
Slc17a4 | Slc16a9 | ENSMUSP00000021769 | ENSMUSP00000047912 | Probable small intestine urate exporter; Acts as a membrane potential-dependent organic anion transporter, the transport requires a low concentration of chloride ions. May be involved in urate extrusion from the intestinal duct. May recognize hydrophilic anionic drugs such as aspirin, salicylate, and ibuprofen as substrates. Able to actively transport inorganic phosphate into cells via Na(+) cotransport (in vitro) (By similarity). Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. | Monocarboxylate transporter 9; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. | 0.681 |
Slc17a4 | Slc23a3 | ENSMUSP00000021769 | ENSMUSP00000027405 | Probable small intestine urate exporter; Acts as a membrane potential-dependent organic anion transporter, the transport requires a low concentration of chloride ions. May be involved in urate extrusion from the intestinal duct. May recognize hydrophilic anionic drugs such as aspirin, salicylate, and ibuprofen as substrates. Able to actively transport inorganic phosphate into cells via Na(+) cotransport (in vitro) (By similarity). Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. | Solute carrier family 23 member 3. | 0.549 |
Slc17a4 | Slc3a1 | ENSMUSP00000021769 | ENSMUSP00000024944 | Probable small intestine urate exporter; Acts as a membrane potential-dependent organic anion transporter, the transport requires a low concentration of chloride ions. May be involved in urate extrusion from the intestinal duct. May recognize hydrophilic anionic drugs such as aspirin, salicylate, and ibuprofen as substrates. Able to actively transport inorganic phosphate into cells via Na(+) cotransport (in vitro) (By similarity). Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. | Neutral and basic amino acid transport protein rBAT; Involved in the high-affinity sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). May function as an activator of SLC7A9 and be involved in the high-affinity reabsorption of cystine in the kidney proximal tubule. | 0.458 |
Slc23a3 | Bcas3 | ENSMUSP00000027405 | ENSMUSP00000074416 | Solute carrier family 23 member 3. | Breast carcinoma-amplified sequence 3 homolog; Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. Binds to chromatin (By similarity). Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation. Belongs to the BCAS3 family. | 0.468 |
Slc23a3 | Cnppd1 | ENSMUSP00000027405 | ENSMUSP00000132688 | Solute carrier family 23 member 3. | Protein CNPPD1. | 0.487 |
Slc23a3 | Mfsd11 | ENSMUSP00000027405 | ENSMUSP00000021173 | Solute carrier family 23 member 3. | UNC93-like protein MFSD11. | 0.448 |
Slc23a3 | Rer1 | ENSMUSP00000027405 | ENSMUSP00000030914 | Solute carrier family 23 member 3. | Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment; Belongs to the RER1 family. | 0.440 |
Slc23a3 | Slc16a9 | ENSMUSP00000027405 | ENSMUSP00000047912 | Solute carrier family 23 member 3. | Monocarboxylate transporter 9; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. | 0.536 |