node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Apmap | Ddx59 | ENSMUSP00000040840 | ENSMUSP00000027655 | Adipocyte plasma membrane-associated protein; Exhibits strong arylesterase activity with beta-naphthyl acetate and phenyl acetate (By similarity). May play a role in adipocyte differentiation. | Probable ATP-dependent RNA helicase DDX59; Belongs to the DEAD box helicase family. DDX59 subfamily. | 0.614 |
Bop1 | Ddx59 | ENSMUSP00000023217 | ENSMUSP00000027655 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | Probable ATP-dependent RNA helicase DDX59; Belongs to the DEAD box helicase family. DDX59 subfamily. | 0.552 |
Bop1 | Nop58 | ENSMUSP00000023217 | ENSMUSP00000140250 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | Nucleolar protein 58; Required for 60S ribosomal subunit biogenesis (By similarity). Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such as U3, U8 and U14 snoRNAs (By similarity). Belongs to the NOP5/NOP56 family. | 0.945 |
Bop1 | Pes1 | ENSMUSP00000023217 | ENSMUSP00000020705 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. | 0.999 |
Bop1 | Wdr12 | ENSMUSP00000023217 | ENSMUSP00000027173 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.999 |
Cep152 | Ddx59 | ENSMUSP00000087208 | ENSMUSP00000027655 | Centrosomal protein of 152 kDa; Necessary for centrosome duplication; the function seems also to involve CEP63, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (By similarity). Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 molecules involved in centriole formation (By similarity). Proposed to snatch PLK4 away from PLK4:CEP92 complexes in early G1 daughter centriole and to reposition PLK4 at the outer boundary of a newly forming CEP152 ring structure (By similarity). Also pla [...] | Probable ATP-dependent RNA helicase DDX59; Belongs to the DEAD box helicase family. DDX59 subfamily. | 0.564 |
Cep152 | Nop58 | ENSMUSP00000087208 | ENSMUSP00000140250 | Centrosomal protein of 152 kDa; Necessary for centrosome duplication; the function seems also to involve CEP63, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (By similarity). Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 molecules involved in centriole formation (By similarity). Proposed to snatch PLK4 away from PLK4:CEP92 complexes in early G1 daughter centriole and to reposition PLK4 at the outer boundary of a newly forming CEP152 ring structure (By similarity). Also pla [...] | Nucleolar protein 58; Required for 60S ribosomal subunit biogenesis (By similarity). Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such as U3, U8 and U14 snoRNAs (By similarity). Belongs to the NOP5/NOP56 family. | 0.920 |
Cep152 | Pes1 | ENSMUSP00000087208 | ENSMUSP00000020705 | Centrosomal protein of 152 kDa; Necessary for centrosome duplication; the function seems also to involve CEP63, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (By similarity). Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 molecules involved in centriole formation (By similarity). Proposed to snatch PLK4 away from PLK4:CEP92 complexes in early G1 daughter centriole and to reposition PLK4 at the outer boundary of a newly forming CEP152 ring structure (By similarity). Also pla [...] | Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. | 0.978 |
Cep152 | Wdr12 | ENSMUSP00000087208 | ENSMUSP00000027173 | Centrosomal protein of 152 kDa; Necessary for centrosome duplication; the function seems also to involve CEP63, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (By similarity). Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 molecules involved in centriole formation (By similarity). Proposed to snatch PLK4 away from PLK4:CEP92 complexes in early G1 daughter centriole and to reposition PLK4 at the outer boundary of a newly forming CEP152 ring structure (By similarity). Also pla [...] | Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.973 |
Ddx59 | Apmap | ENSMUSP00000027655 | ENSMUSP00000040840 | Probable ATP-dependent RNA helicase DDX59; Belongs to the DEAD box helicase family. DDX59 subfamily. | Adipocyte plasma membrane-associated protein; Exhibits strong arylesterase activity with beta-naphthyl acetate and phenyl acetate (By similarity). May play a role in adipocyte differentiation. | 0.614 |
Ddx59 | Bop1 | ENSMUSP00000027655 | ENSMUSP00000023217 | Probable ATP-dependent RNA helicase DDX59; Belongs to the DEAD box helicase family. DDX59 subfamily. | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.552 |
Ddx59 | Cep152 | ENSMUSP00000027655 | ENSMUSP00000087208 | Probable ATP-dependent RNA helicase DDX59; Belongs to the DEAD box helicase family. DDX59 subfamily. | Centrosomal protein of 152 kDa; Necessary for centrosome duplication; the function seems also to involve CEP63, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (By similarity). Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 molecules involved in centriole formation (By similarity). Proposed to snatch PLK4 away from PLK4:CEP92 complexes in early G1 daughter centriole and to reposition PLK4 at the outer boundary of a newly forming CEP152 ring structure (By similarity). Also pla [...] | 0.564 |
Ddx59 | Ino80e | ENSMUSP00000027655 | ENSMUSP00000049851 | Probable ATP-dependent RNA helicase DDX59; Belongs to the DEAD box helicase family. DDX59 subfamily. | INO80 complex subunit E. | 0.668 |
Ddx59 | Nop58 | ENSMUSP00000027655 | ENSMUSP00000140250 | Probable ATP-dependent RNA helicase DDX59; Belongs to the DEAD box helicase family. DDX59 subfamily. | Nucleolar protein 58; Required for 60S ribosomal subunit biogenesis (By similarity). Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such as U3, U8 and U14 snoRNAs (By similarity). Belongs to the NOP5/NOP56 family. | 0.621 |
Ddx59 | Pes1 | ENSMUSP00000027655 | ENSMUSP00000020705 | Probable ATP-dependent RNA helicase DDX59; Belongs to the DEAD box helicase family. DDX59 subfamily. | Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. | 0.602 |
Ddx59 | Tbc1d32 | ENSMUSP00000027655 | ENSMUSP00000097328 | Probable ATP-dependent RNA helicase DDX59; Belongs to the DEAD box helicase family. DDX59 subfamily. | Protein broad-minded; Required for high-level Shh responses in the developing neural tube. Together with CDK20, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to Shh signaling. | 0.580 |
Ddx59 | Tctn3 | ENSMUSP00000027655 | ENSMUSP00000025981 | Probable ATP-dependent RNA helicase DDX59; Belongs to the DEAD box helicase family. DDX59 subfamily. | Tectonic-3; Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. May be involved in apoptosis regulation (By similarity). Necessary for signal transduction through the sonic hedgehog (Shh) signaling pathway. | 0.580 |
Ddx59 | Wdr12 | ENSMUSP00000027655 | ENSMUSP00000027173 | Probable ATP-dependent RNA helicase DDX59; Belongs to the DEAD box helicase family. DDX59 subfamily. | Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.603 |
Ddx59 | Znhit2 | ENSMUSP00000027655 | ENSMUSP00000134031 | Probable ATP-dependent RNA helicase DDX59; Belongs to the DEAD box helicase family. DDX59 subfamily. | Zinc finger HIT domain-containing protein 2; May act as a bridging factor mediating the interaction between the R2TP/Prefoldin-like (R2TP/PFDL) complex and U5 small nuclear ribonucleoprotein (U5 snRNP) (By similarity). Required for the interaction of R2TP complex subunit RPAP3 and prefoldin-like subunit URI1 with U5 snRNP proteins EFTUD2 and PRPF8 (By similarity). May play a role in regulating the composition of the U5 snRNP complex (By similarity). | 0.591 |
Ino80e | Ddx59 | ENSMUSP00000049851 | ENSMUSP00000027655 | INO80 complex subunit E. | Probable ATP-dependent RNA helicase DDX59; Belongs to the DEAD box helicase family. DDX59 subfamily. | 0.668 |