node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ccm2 | Efcab2 | ENSMUSP00000000388 | ENSMUSP00000027775 | Cerebral cavernous malformations protein 2 homolog; Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions. May also function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock. | Dynein regulatory complex protein 8; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. | 0.519 |
Efcab11 | Efcab2 | ENSMUSP00000044808 | ENSMUSP00000027775 | EF-hand calcium-binding domain-containing protein 11. | Dynein regulatory complex protein 8; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. | 0.575 |
Efcab2 | Ccm2 | ENSMUSP00000027775 | ENSMUSP00000000388 | Dynein regulatory complex protein 8; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. | Cerebral cavernous malformations protein 2 homolog; Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions. May also function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock. | 0.519 |
Efcab2 | Efcab11 | ENSMUSP00000027775 | ENSMUSP00000044808 | Dynein regulatory complex protein 8; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. | EF-hand calcium-binding domain-containing protein 11. | 0.575 |
Efcab2 | Gin1 | ENSMUSP00000027775 | ENSMUSP00000108464 | Dynein regulatory complex protein 8; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. | Gypsy retrotransposon integrase-like protein 1. | 0.705 |
Efcab2 | Hrc | ENSMUSP00000027775 | ENSMUSP00000082459 | Dynein regulatory complex protein 8; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. | Histidine-rich calcium-binding protein. | 0.588 |
Efcab2 | Pgbd1 | ENSMUSP00000027775 | ENSMUSP00000097307 | Dynein regulatory complex protein 8; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. | PiggyBac transposable element-derived 1. | 0.513 |
Efcab2 | Ppef2 | ENSMUSP00000027775 | ENSMUSP00000144157 | Dynein regulatory complex protein 8; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. | Serine/threonine-protein phosphatase with EF-hands 2; May play a role in phototransduction. May dephosphorylate photoactivated rhodopsin. May function as a calcium sensing regulator of ionic currents, energy production or synaptic transmission; Belongs to the PPP phosphatase family. | 0.649 |
Efcab2 | Pskh1 | ENSMUSP00000027775 | ENSMUSP00000061700 | Dynein regulatory complex protein 8; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. | Serine/threonine-protein kinase H1; May be a SFC-associated serine kinase (splicing factor compartment-associated serine kinase) with a role in intranuclear SR protein (non-snRNP splicing factors containing a serine/arginine-rich domain) trafficking and pre-mRNA processing. | 0.548 |
Efcab2 | Tax1bp1 | ENSMUSP00000027775 | ENSMUSP00000079548 | Dynein regulatory complex protein 8; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. | Tax1-binding protein 1 homolog; Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti- apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade (By similarity). | 0.553 |
Efcab2 | Tcte1 | ENSMUSP00000027775 | ENSMUSP00000109175 | Dynein regulatory complex protein 8; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. | Dynein regulatory complex subunit 5; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. May play a role in the assembly of N-DRC (By similarity). Required for sperm motility. | 0.535 |
Efcab2 | Wdr63 | ENSMUSP00000027775 | ENSMUSP00000124475 | Dynein regulatory complex protein 8; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. | WD repeat domain 63. | 0.518 |
Gin1 | Efcab2 | ENSMUSP00000108464 | ENSMUSP00000027775 | Gypsy retrotransposon integrase-like protein 1. | Dynein regulatory complex protein 8; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. | 0.705 |
Gin1 | Pgbd1 | ENSMUSP00000108464 | ENSMUSP00000097307 | Gypsy retrotransposon integrase-like protein 1. | PiggyBac transposable element-derived 1. | 0.585 |
Hrc | Efcab2 | ENSMUSP00000082459 | ENSMUSP00000027775 | Histidine-rich calcium-binding protein. | Dynein regulatory complex protein 8; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. | 0.588 |
Pgbd1 | Efcab2 | ENSMUSP00000097307 | ENSMUSP00000027775 | PiggyBac transposable element-derived 1. | Dynein regulatory complex protein 8; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. | 0.513 |
Pgbd1 | Gin1 | ENSMUSP00000097307 | ENSMUSP00000108464 | PiggyBac transposable element-derived 1. | Gypsy retrotransposon integrase-like protein 1. | 0.585 |
Ppef2 | Efcab2 | ENSMUSP00000144157 | ENSMUSP00000027775 | Serine/threonine-protein phosphatase with EF-hands 2; May play a role in phototransduction. May dephosphorylate photoactivated rhodopsin. May function as a calcium sensing regulator of ionic currents, energy production or synaptic transmission; Belongs to the PPP phosphatase family. | Dynein regulatory complex protein 8; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. | 0.649 |
Ppef2 | Pskh1 | ENSMUSP00000144157 | ENSMUSP00000061700 | Serine/threonine-protein phosphatase with EF-hands 2; May play a role in phototransduction. May dephosphorylate photoactivated rhodopsin. May function as a calcium sensing regulator of ionic currents, energy production or synaptic transmission; Belongs to the PPP phosphatase family. | Serine/threonine-protein kinase H1; May be a SFC-associated serine kinase (splicing factor compartment-associated serine kinase) with a role in intranuclear SR protein (non-snRNP splicing factors containing a serine/arginine-rich domain) trafficking and pre-mRNA processing. | 0.547 |
Pskh1 | Efcab2 | ENSMUSP00000061700 | ENSMUSP00000027775 | Serine/threonine-protein kinase H1; May be a SFC-associated serine kinase (splicing factor compartment-associated serine kinase) with a role in intranuclear SR protein (non-snRNP splicing factors containing a serine/arginine-rich domain) trafficking and pre-mRNA processing. | Dynein regulatory complex protein 8; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. | 0.548 |