node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cisd3 | Fam83c | ENSMUSP00000103209 | ENSMUSP00000029143 | CDGSH iron-sulfur domain-containing protein 3, mitochondrial; Can transfer its iron-sulfur clusters to the apoferrodoxins FDX1 and FDX2. Contributes to mitochondrial iron homeostasis and in maintaining normal levels of free iron and reactive oxygen species, and thereby contributes to normal mitochondrial function. Belongs to the CISD protein family. | Protein FAM83C; May play a role in MAPK signaling. Belongs to the FAM83 family. | 0.608 |
Cisd3 | Mrpl23 | ENSMUSP00000103209 | ENSMUSP00000039784 | CDGSH iron-sulfur domain-containing protein 3, mitochondrial; Can transfer its iron-sulfur clusters to the apoferrodoxins FDX1 and FDX2. Contributes to mitochondrial iron homeostasis and in maintaining normal levels of free iron and reactive oxygen species, and thereby contributes to normal mitochondrial function. Belongs to the CISD protein family. | 39S ribosomal protein L23, mitochondrial; Belongs to the universal ribosomal protein uL23 family. | 0.581 |
Eva1c | Fam83c | ENSMUSP00000036695 | ENSMUSP00000029143 | Protein eva-1 homolog C; Binds heparin; Belongs to the EVA1 family. | Protein FAM83C; May play a role in MAPK signaling. Belongs to the FAM83 family. | 0.469 |
Eva1c | Susd1 | ENSMUSP00000036695 | ENSMUSP00000048201 | Protein eva-1 homolog C; Binds heparin; Belongs to the EVA1 family. | Sushi domain-containing 1. | 0.495 |
Fam83c | Cisd3 | ENSMUSP00000029143 | ENSMUSP00000103209 | Protein FAM83C; May play a role in MAPK signaling. Belongs to the FAM83 family. | CDGSH iron-sulfur domain-containing protein 3, mitochondrial; Can transfer its iron-sulfur clusters to the apoferrodoxins FDX1 and FDX2. Contributes to mitochondrial iron homeostasis and in maintaining normal levels of free iron and reactive oxygen species, and thereby contributes to normal mitochondrial function. Belongs to the CISD protein family. | 0.608 |
Fam83c | Eva1c | ENSMUSP00000029143 | ENSMUSP00000036695 | Protein FAM83C; May play a role in MAPK signaling. Belongs to the FAM83 family. | Protein eva-1 homolog C; Binds heparin; Belongs to the EVA1 family. | 0.469 |
Fam83c | Kif22 | ENSMUSP00000029143 | ENSMUSP00000032915 | Protein FAM83C; May play a role in MAPK signaling. Belongs to the FAM83 family. | Kinesin-like protein KIF22; Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA. Plays a role in congression of laterally attached chromosomes in NDC80-depleted cells. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.591 |
Fam83c | Mrpl23 | ENSMUSP00000029143 | ENSMUSP00000039784 | Protein FAM83C; May play a role in MAPK signaling. Belongs to the FAM83 family. | 39S ribosomal protein L23, mitochondrial; Belongs to the universal ribosomal protein uL23 family. | 0.538 |
Fam83c | Pgbd5 | ENSMUSP00000029143 | ENSMUSP00000054788 | Protein FAM83C; May play a role in MAPK signaling. Belongs to the FAM83 family. | PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. | 0.638 |
Fam83c | Rbm33 | ENSMUSP00000029143 | ENSMUSP00000062449 | Protein FAM83C; May play a role in MAPK signaling. Belongs to the FAM83 family. | RNA-binding protein 33. | 0.671 |
Fam83c | Spef2 | ENSMUSP00000029143 | ENSMUSP00000035762 | Protein FAM83C; May play a role in MAPK signaling. Belongs to the FAM83 family. | Sperm flagellar protein 2; Required for correct axoneme development in spermatozoa. Important for normal development of the manchette and sperm head morphology. Essential for male fertility. Plays a role in localization of the intraflagellar transport protein IFT20 to the manchette, suggesting function as an adapter for dynein-mediated protein transport during spermatogenesis. Also plays a role in bone growth where it seems to be required for normal osteoblast differentiation. | 0.452 |
Fam83c | Susd1 | ENSMUSP00000029143 | ENSMUSP00000048201 | Protein FAM83C; May play a role in MAPK signaling. Belongs to the FAM83 family. | Sushi domain-containing 1. | 0.478 |
Fam83c | Ttbk2 | ENSMUSP00000029143 | ENSMUSP00000028740 | Protein FAM83C; May play a role in MAPK signaling. Belongs to the FAM83 family. | Tau-tubulin kinase 2; Serine/threonine kinase that acts as a key regulator of ciliogenesis: controls the initiation of ciliogenesis by binding to the distal end of the basal body and promoting the removal of CCP110, which caps the mother centriole, leading to the recruitment of IFT proteins, which build the ciliary axoneme. Has some substrate preference for proteins that are already phosphorylated on a Tyr residue at the +2 position relative to the phosphorylation site. Able to phosphorylate tau on serines in vitro. | 0.603 |
Fam83c | Zfp91 | ENSMUSP00000029143 | ENSMUSP00000037971 | Protein FAM83C; May play a role in MAPK signaling. Belongs to the FAM83 family. | E3 ubiquitin-protein ligase ZFP91; Atypical E3 ubiquitin-protein ligase that mediates 'Lys-63'- linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby acts as an activator of the non-canonical NF- kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.482 |
Kif22 | Fam83c | ENSMUSP00000032915 | ENSMUSP00000029143 | Kinesin-like protein KIF22; Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA. Plays a role in congression of laterally attached chromosomes in NDC80-depleted cells. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Protein FAM83C; May play a role in MAPK signaling. Belongs to the FAM83 family. | 0.591 |
Mrpl23 | Cisd3 | ENSMUSP00000039784 | ENSMUSP00000103209 | 39S ribosomal protein L23, mitochondrial; Belongs to the universal ribosomal protein uL23 family. | CDGSH iron-sulfur domain-containing protein 3, mitochondrial; Can transfer its iron-sulfur clusters to the apoferrodoxins FDX1 and FDX2. Contributes to mitochondrial iron homeostasis and in maintaining normal levels of free iron and reactive oxygen species, and thereby contributes to normal mitochondrial function. Belongs to the CISD protein family. | 0.581 |
Mrpl23 | Fam83c | ENSMUSP00000039784 | ENSMUSP00000029143 | 39S ribosomal protein L23, mitochondrial; Belongs to the universal ribosomal protein uL23 family. | Protein FAM83C; May play a role in MAPK signaling. Belongs to the FAM83 family. | 0.538 |
Pgbd5 | Fam83c | ENSMUSP00000054788 | ENSMUSP00000029143 | PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. | Protein FAM83C; May play a role in MAPK signaling. Belongs to the FAM83 family. | 0.638 |
Pgbd5 | Rbm33 | ENSMUSP00000054788 | ENSMUSP00000062449 | PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. | RNA-binding protein 33. | 0.616 |
Rbm33 | Fam83c | ENSMUSP00000062449 | ENSMUSP00000029143 | RNA-binding protein 33. | Protein FAM83C; May play a role in MAPK signaling. Belongs to the FAM83 family. | 0.671 |