node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ccdc113 | Exoc3l4 | ENSMUSP00000049497 | ENSMUSP00000152337 | Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation. | Exocyst complex component 3-like protein 4; Belongs to the SEC6 family. | 0.483 |
Ccdc113 | Iqcj | ENSMUSP00000049497 | ENSMUSP00000069544 | Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation. | IQ domain-containing protein J. | 0.491 |
Ccdc113 | Schip1 | ENSMUSP00000049497 | ENSMUSP00000029346 | Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation. | Schwannomin-interacting protein 1; Belongs to the SCHIP1 family. | 0.400 |
Ccdc180 | Schip1 | ENSMUSP00000136714 | ENSMUSP00000029346 | Coiled-coil domain-containing 180. | Schwannomin-interacting protein 1; Belongs to the SCHIP1 family. | 0.431 |
Exoc3l4 | Ccdc113 | ENSMUSP00000152337 | ENSMUSP00000049497 | Exocyst complex component 3-like protein 4; Belongs to the SEC6 family. | Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation. | 0.483 |
Exoc3l4 | Iqcj | ENSMUSP00000152337 | ENSMUSP00000069544 | Exocyst complex component 3-like protein 4; Belongs to the SEC6 family. | IQ domain-containing protein J. | 0.542 |
Exoc3l4 | Schip1 | ENSMUSP00000152337 | ENSMUSP00000029346 | Exocyst complex component 3-like protein 4; Belongs to the SEC6 family. | Schwannomin-interacting protein 1; Belongs to the SCHIP1 family. | 0.414 |
Iqcj | Ccdc113 | ENSMUSP00000069544 | ENSMUSP00000049497 | IQ domain-containing protein J. | Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation. | 0.491 |
Iqcj | Exoc3l4 | ENSMUSP00000069544 | ENSMUSP00000152337 | IQ domain-containing protein J. | Exocyst complex component 3-like protein 4; Belongs to the SEC6 family. | 0.542 |
Iqcj | Schip1 | ENSMUSP00000069544 | ENSMUSP00000029346 | IQ domain-containing protein J. | Schwannomin-interacting protein 1; Belongs to the SCHIP1 family. | 0.867 |
Nf2 | Schip1 | ENSMUSP00000105536 | ENSMUSP00000029346 | Merlin; Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF [...] | Schwannomin-interacting protein 1; Belongs to the SCHIP1 family. | 0.597 |
Nf2 | Taok1 | ENSMUSP00000105536 | ENSMUSP00000055470 | Merlin; Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF [...] | Serine/threonine-protein kinase TAO1; Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK1 [...] | 0.502 |
Schip1 | Ccdc113 | ENSMUSP00000029346 | ENSMUSP00000049497 | Schwannomin-interacting protein 1; Belongs to the SCHIP1 family. | Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation. | 0.400 |
Schip1 | Ccdc180 | ENSMUSP00000029346 | ENSMUSP00000136714 | Schwannomin-interacting protein 1; Belongs to the SCHIP1 family. | Coiled-coil domain-containing 180. | 0.431 |
Schip1 | Exoc3l4 | ENSMUSP00000029346 | ENSMUSP00000152337 | Schwannomin-interacting protein 1; Belongs to the SCHIP1 family. | Exocyst complex component 3-like protein 4; Belongs to the SEC6 family. | 0.414 |
Schip1 | Iqcj | ENSMUSP00000029346 | ENSMUSP00000069544 | Schwannomin-interacting protein 1; Belongs to the SCHIP1 family. | IQ domain-containing protein J. | 0.867 |
Schip1 | Nf2 | ENSMUSP00000029346 | ENSMUSP00000105536 | Schwannomin-interacting protein 1; Belongs to the SCHIP1 family. | Merlin; Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF [...] | 0.597 |
Schip1 | Taok1 | ENSMUSP00000029346 | ENSMUSP00000055470 | Schwannomin-interacting protein 1; Belongs to the SCHIP1 family. | Serine/threonine-protein kinase TAO1; Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK1 [...] | 0.538 |
Schip1 | Taok2 | ENSMUSP00000029346 | ENSMUSP00000112963 | Schwannomin-interacting protein 1; Belongs to the SCHIP1 family. | Serine/threonine-protein kinase TAO2; Serine/threonine-protein kinase involved in different processes such as membrane blebbing and apoptotic bodies formation DNA damage response and MAPK14/p38 MAPK stress-activated MAPK cascade. Phosphorylates itself, MBP, activated MAPK8, MAP2K3, MAP2K6 and tubulins. Activates the MAPK14/p38 MAPK signaling pathway through the specific activation and phosphorylation of the upstream MAP2K3 and MAP2K6 kinases. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress- activated MAPK cascade, pro [...] | 0.777 |
Schip1 | Tmem164 | ENSMUSP00000029346 | ENSMUSP00000108517 | Schwannomin-interacting protein 1; Belongs to the SCHIP1 family. | Transmembrane protein 164. | 0.403 |