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Cyp2j6 protein (mouse) - STRING interaction network
"Cyp2j6" - Cytochrome P450, family 2, subfamily j, polypeptide 6 in Mus musculus
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Cyp2j6Cytochrome P450, family 2, subfamily j, polypeptide 6 (501 aa)    
Predicted Functional Partners:
Cyp4b1
Cytochrome P450 4B1; Responsible for mutagenic activation of 3-methoxy-4- aminoazobenzene (3-MeO-AAB); a potent procarcinogen. Also active on 2-aminofluorene and 2-aminoanthracene; Belongs to the cytochrome P450 family (511 aa)
   
 
0.934
Cyp3a11
Cytochrome P450 3A11; Catalyzes erythromycin N-demethylation, nifedipine oxidation and testosterone 6 beta-hydroxylation; Belongs to the cytochrome P450 family (504 aa)
   
0.929
Cyp3a25
Cytochrome P450 3A25; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics (503 aa)
   
0.929
Cyp4a12a
Cytochrome P450 4A12A; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics (508 aa)
   
 
0.927
Cyp3a13
Cytochrome P450 3A13; Can activate aflatoxin B1 to a genotoxic product (503 aa)
   
0.926
Aox1
Aldehyde oxidase 1; Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide, N- methylphthalazinium and phthalazine, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antiviral agent. Also plays a role in the reductive metabolism of the xenobiotic imi [...] (1333 aa)
     
 
  0.919
Cyp3a41a
Cytochrome P450, family 3, subfamily a, polypeptide 41A (504 aa)
   
0.918
Cyp3a41b
Cytochrome P450, family 3, subfamily a, polypeptide 41B (504 aa)
   
0.918
Cyp3a16
Cytochrome P450 3A16; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics (504 aa)
   
0.918
Cyp1a2
Cytochrome P450 1A2; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation (513 aa)
   
 
0.916
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus muscaris, Mus musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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