node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Crisp2 | Eqtn | ENSMUSP00000156411 | ENSMUSP00000030309 | Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. Belongs to the CRISP family. | Equatorin; Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis. | 0.414 |
Crisp2 | Izumo1 | ENSMUSP00000156411 | ENSMUSP00000033100 | Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. Belongs to the CRISP family. | Izumo sperm-egg fusion protein 1; Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. | 0.582 |
Eqtn | Crisp2 | ENSMUSP00000030309 | ENSMUSP00000156411 | Equatorin; Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis. | Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. Belongs to the CRISP family. | 0.414 |
Eqtn | Erich6 | ENSMUSP00000030309 | ENSMUSP00000040882 | Equatorin; Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis. | Glutamate-rich protein 6; Belongs to the ERICH6 family. | 0.494 |
Eqtn | Izumo1 | ENSMUSP00000030309 | ENSMUSP00000033100 | Equatorin; Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis. | Izumo sperm-egg fusion protein 1; Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. | 0.539 |
Eqtn | Lrrc57 | ENSMUSP00000030309 | ENSMUSP00000099555 | Equatorin; Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis. | Leucine-rich repeat-containing protein 57. | 0.455 |
Eqtn | Mob3b | ENSMUSP00000030309 | ENSMUSP00000100040 | Equatorin; Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis. | MOB kinase activator 3B; Modulates LATS1 expression in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. | 0.489 |
Eqtn | Mrps25 | ENSMUSP00000030309 | ENSMUSP00000114402 | Equatorin; Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis. | 28S ribosomal protein S25, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mS25 family. | 0.457 |
Eqtn | Pan3 | ENSMUSP00000030309 | ENSMUSP00000031651 | Equatorin; Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis. | PAN2-PAN3 deadenylation complex subunit Pan3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] | 0.602 |
Eqtn | Pcna | ENSMUSP00000030309 | ENSMUSP00000028817 | Equatorin; Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis. | Proliferating cell nuclear antigen; Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'- phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA rep [...] | 0.560 |
Eqtn | Spesp1 | ENSMUSP00000030309 | ENSMUSP00000058522 | Equatorin; Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis. | Sperm equatorial segment protein 1; Involved in fertilization ability of sperm. | 0.508 |
Eqtn | Yars | ENSMUSP00000030309 | ENSMUSP00000101669 | Equatorin; Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis. | Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.414 |
Erich6 | Eqtn | ENSMUSP00000040882 | ENSMUSP00000030309 | Glutamate-rich protein 6; Belongs to the ERICH6 family. | Equatorin; Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis. | 0.494 |
Erich6 | Lrrc57 | ENSMUSP00000040882 | ENSMUSP00000099555 | Glutamate-rich protein 6; Belongs to the ERICH6 family. | Leucine-rich repeat-containing protein 57. | 0.542 |
Erich6 | Mrps25 | ENSMUSP00000040882 | ENSMUSP00000114402 | Glutamate-rich protein 6; Belongs to the ERICH6 family. | 28S ribosomal protein S25, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mS25 family. | 0.572 |
Izumo1 | Crisp2 | ENSMUSP00000033100 | ENSMUSP00000156411 | Izumo sperm-egg fusion protein 1; Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. | Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. Belongs to the CRISP family. | 0.582 |
Izumo1 | Eqtn | ENSMUSP00000033100 | ENSMUSP00000030309 | Izumo sperm-egg fusion protein 1; Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. | Equatorin; Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis. | 0.539 |
Izumo1 | Spesp1 | ENSMUSP00000033100 | ENSMUSP00000058522 | Izumo sperm-egg fusion protein 1; Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. | Sperm equatorial segment protein 1; Involved in fertilization ability of sperm. | 0.547 |
Lrrc57 | Eqtn | ENSMUSP00000099555 | ENSMUSP00000030309 | Leucine-rich repeat-containing protein 57. | Equatorin; Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis. | 0.455 |
Lrrc57 | Erich6 | ENSMUSP00000099555 | ENSMUSP00000040882 | Leucine-rich repeat-containing protein 57. | Glutamate-rich protein 6; Belongs to the ERICH6 family. | 0.542 |