node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arl2bp | Eaf1 | ENSMUSP00000034228 | ENSMUSP00000022446 | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 (By similarity). | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | 0.485 |
Arl2bp | Efcab1 | ENSMUSP00000034228 | ENSMUSP00000087744 | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 (By similarity). | EF-hand calcium-binding domain-containing protein 1. | 0.537 |
Arl2bp | Fkbp14 | ENSMUSP00000034228 | ENSMUSP00000046070 | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 (By similarity). | Peptidyl-prolyl cis-trans isomerase FKBP14; PPIase which accelerates the folding of proteins during protein synthesis. Has a preference for substrates containing 4- hydroxylproline modifications, including type III collagen. May also target type VI and type X collagens. | 0.437 |
Arl2bp | Gpatch3 | ENSMUSP00000034228 | ENSMUSP00000030662 | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 (By similarity). | G patch domain-containing protein 3; Involved in transcriptional regulation. It is able to activate transcription from CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development. Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signaling and inhibition of type I interferon production. The control mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins implicated in antiviral response, such as TBK1 and TRAF6. | 0.555 |
Arl2bp | Mettl6 | ENSMUSP00000034228 | ENSMUSP00000077138 | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 (By similarity). | tRNA N(3)-methylcytidine methyltransferase METTL6; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Ser); Belongs to the methyltransferase superfamily. METL family. | 0.476 |
Arl2bp | Rspry1 | ENSMUSP00000034228 | ENSMUSP00000057275 | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 (By similarity). | RING finger and SPRY domain-containing protein 1. | 0.655 |
Arl2bp | Znrf2 | ENSMUSP00000034228 | ENSMUSP00000078795 | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 (By similarity). | E3 ubiquitin-protein ligase ZNRF2; May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. | 0.517 |
Eaf1 | Arl2bp | ENSMUSP00000022446 | ENSMUSP00000034228 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 (By similarity). | 0.485 |
Eaf1 | Efcab1 | ENSMUSP00000022446 | ENSMUSP00000087744 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | EF-hand calcium-binding domain-containing protein 1. | 0.626 |
Eaf1 | Fkbp14 | ENSMUSP00000022446 | ENSMUSP00000046070 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | Peptidyl-prolyl cis-trans isomerase FKBP14; PPIase which accelerates the folding of proteins during protein synthesis. Has a preference for substrates containing 4- hydroxylproline modifications, including type III collagen. May also target type VI and type X collagens. | 0.497 |
Eaf1 | Gpatch3 | ENSMUSP00000022446 | ENSMUSP00000030662 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | G patch domain-containing protein 3; Involved in transcriptional regulation. It is able to activate transcription from CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development. Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signaling and inhibition of type I interferon production. The control mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins implicated in antiviral response, such as TBK1 and TRAF6. | 0.654 |
Eaf1 | Mettl6 | ENSMUSP00000022446 | ENSMUSP00000077138 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | tRNA N(3)-methylcytidine methyltransferase METTL6; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Ser); Belongs to the methyltransferase superfamily. METL family. | 0.692 |
Eaf1 | Rspry1 | ENSMUSP00000022446 | ENSMUSP00000057275 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | RING finger and SPRY domain-containing protein 1. | 0.667 |
Eaf1 | Znrf2 | ENSMUSP00000022446 | ENSMUSP00000078795 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | E3 ubiquitin-protein ligase ZNRF2; May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. | 0.566 |
Efcab1 | Arl2bp | ENSMUSP00000087744 | ENSMUSP00000034228 | EF-hand calcium-binding domain-containing protein 1. | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 (By similarity). | 0.537 |
Efcab1 | Eaf1 | ENSMUSP00000087744 | ENSMUSP00000022446 | EF-hand calcium-binding domain-containing protein 1. | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | 0.626 |
Efcab1 | Fkbp14 | ENSMUSP00000087744 | ENSMUSP00000046070 | EF-hand calcium-binding domain-containing protein 1. | Peptidyl-prolyl cis-trans isomerase FKBP14; PPIase which accelerates the folding of proteins during protein synthesis. Has a preference for substrates containing 4- hydroxylproline modifications, including type III collagen. May also target type VI and type X collagens. | 0.586 |
Efcab1 | Gpatch3 | ENSMUSP00000087744 | ENSMUSP00000030662 | EF-hand calcium-binding domain-containing protein 1. | G patch domain-containing protein 3; Involved in transcriptional regulation. It is able to activate transcription from CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development. Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signaling and inhibition of type I interferon production. The control mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins implicated in antiviral response, such as TBK1 and TRAF6. | 0.667 |
Efcab1 | Mettl6 | ENSMUSP00000087744 | ENSMUSP00000077138 | EF-hand calcium-binding domain-containing protein 1. | tRNA N(3)-methylcytidine methyltransferase METTL6; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Ser); Belongs to the methyltransferase superfamily. METL family. | 0.554 |
Efcab1 | Rspry1 | ENSMUSP00000087744 | ENSMUSP00000057275 | EF-hand calcium-binding domain-containing protein 1. | RING finger and SPRY domain-containing protein 1. | 0.687 |