node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cetn1 | Morn1 | ENSMUSP00000057392 | ENSMUSP00000030915 | Centrin-1; Plays a fundamental role in microtubule-organizing center structure and function (By similarity). Plays a role in sperm cilia formation ; Belongs to the centrin family. | MORN repeat-containing 1. | 0.747 |
Cetn1 | Prss28 | ENSMUSP00000057392 | ENSMUSP00000015267 | Centrin-1; Plays a fundamental role in microtubule-organizing center structure and function (By similarity). Plays a role in sperm cilia formation ; Belongs to the centrin family. | Serine protease 28; Involved in embryo hatching and implantation. | 0.493 |
Cetn2 | Morn1 | ENSMUSP00000110198 | ENSMUSP00000030915 | Centrin-2; Plays a fundamental role in microtubule organizing center structure and function. Required for centriole duplication and correct spindle formation. Has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CCP110 (By similarity). The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, Xpa, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortio [...] | MORN repeat-containing 1. | 0.723 |
Cetn2 | Tbccd1 | ENSMUSP00000110198 | ENSMUSP00000004576 | Centrin-2; Plays a fundamental role in microtubule organizing center structure and function. Required for centriole duplication and correct spindle formation. Has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CCP110 (By similarity). The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, Xpa, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortio [...] | TBCC domain-containing protein 1; Plays a role in the regulation of centrosome and Golgi apparatus positioning, with consequences on cell shape and cell migration; Belongs to the TBCC family. | 0.577 |
Cetn4 | Morn1 | ENSMUSP00000100020 | ENSMUSP00000030915 | Centrin-4; Ca(2+)-binding protein that may be involved in basal body assembly or in a subsequent step of ciliogenesis. | MORN repeat-containing 1. | 0.604 |
Cetn4 | Tbccd1 | ENSMUSP00000100020 | ENSMUSP00000004576 | Centrin-4; Ca(2+)-binding protein that may be involved in basal body assembly or in a subsequent step of ciliogenesis. | TBCC domain-containing protein 1; Plays a role in the regulation of centrosome and Golgi apparatus positioning, with consequences on cell shape and cell migration; Belongs to the TBCC family. | 0.758 |
Dhfr | Morn1 | ENSMUSP00000022218 | ENSMUSP00000030915 | Dihydrofolate reductase; Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA. | MORN repeat-containing 1. | 0.518 |
Dhfr | Shld1 | ENSMUSP00000022218 | ENSMUSP00000105759 | Dihydrofolate reductase; Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA. | Shieldin complex subunit 1; Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection. Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres. | 0.464 |
Morn1 | Cetn1 | ENSMUSP00000030915 | ENSMUSP00000057392 | MORN repeat-containing 1. | Centrin-1; Plays a fundamental role in microtubule-organizing center structure and function (By similarity). Plays a role in sperm cilia formation ; Belongs to the centrin family. | 0.747 |
Morn1 | Cetn2 | ENSMUSP00000030915 | ENSMUSP00000110198 | MORN repeat-containing 1. | Centrin-2; Plays a fundamental role in microtubule organizing center structure and function. Required for centriole duplication and correct spindle formation. Has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CCP110 (By similarity). The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, Xpa, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortio [...] | 0.723 |
Morn1 | Cetn4 | ENSMUSP00000030915 | ENSMUSP00000100020 | MORN repeat-containing 1. | Centrin-4; Ca(2+)-binding protein that may be involved in basal body assembly or in a subsequent step of ciliogenesis. | 0.604 |
Morn1 | Dhfr | ENSMUSP00000030915 | ENSMUSP00000022218 | MORN repeat-containing 1. | Dihydrofolate reductase; Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA. | 0.518 |
Morn1 | Morn2 | ENSMUSP00000030915 | ENSMUSP00000051408 | MORN repeat-containing 1. | MORN repeat-containing protein 2; Might have a role in spermatogenesis. | 0.702 |
Morn1 | Morn5 | ENSMUSP00000030915 | ENSMUSP00000028256 | MORN repeat-containing 1. | MORN repeat-containing protein 5. | 0.579 |
Morn1 | Prss28 | ENSMUSP00000030915 | ENSMUSP00000015267 | MORN repeat-containing 1. | Serine protease 28; Involved in embryo hatching and implantation. | 0.696 |
Morn1 | Shld1 | ENSMUSP00000030915 | ENSMUSP00000105759 | MORN repeat-containing 1. | Shieldin complex subunit 1; Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection. Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres. | 0.535 |
Morn1 | Tbccd1 | ENSMUSP00000030915 | ENSMUSP00000004576 | MORN repeat-containing 1. | TBCC domain-containing protein 1; Plays a role in the regulation of centrosome and Golgi apparatus positioning, with consequences on cell shape and cell migration; Belongs to the TBCC family. | 0.701 |
Morn1 | Wac | ENSMUSP00000030915 | ENSMUSP00000132117 | MORN repeat-containing 1. | WW domain-containing adapter protein with coiled-coil; Acts as a linker between gene transcription and histone H2B monoubiquitination at 'Lys-120' (H2BK120ub1). Interacts with the RNA polymerase II transcriptional machinery via its WW domain and with RNF20-RNF40 via its coiled coil region, thereby linking and regulating H2BK120ub1 and gene transcription. Regulates the cell-cycle checkpoint activation in response to DNA damage. Positive regulator of amino acid starvation-induced autophagy. Also acts as a negative regulator of basal autophagy. Positively regulates MTOR activity by promot [...] | 0.515 |
Morn2 | Morn1 | ENSMUSP00000051408 | ENSMUSP00000030915 | MORN repeat-containing protein 2; Might have a role in spermatogenesis. | MORN repeat-containing 1. | 0.702 |
Morn5 | Morn1 | ENSMUSP00000028256 | ENSMUSP00000030915 | MORN repeat-containing protein 5. | MORN repeat-containing 1. | 0.579 |