node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Acvr2b | Cfc1 | ENSMUSP00000126108 | ENSMUSP00000027298 | Activin receptor type-2B; Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c). Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to [...] | Cryptic protein; Nodal coreceptor involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. | 0.900 |
Acvr2b | Creld1 | ENSMUSP00000126108 | ENSMUSP00000032422 | Activin receptor type-2B; Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c). Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to [...] | Protein disulfide isomerase Creld1; Protein disulfide isomerase (By similarity). Promotes the localization of acetylcholine receptors (AChRs) to the plasma membrane ; Belongs to the CRELD family. | 0.451 |
Acvr2b | Gdf1 | ENSMUSP00000126108 | ENSMUSP00000146749 | Activin receptor type-2B; Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c). Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to [...] | Growth differentiation factor 1. | 0.805 |
Acvr2b | Nodal | ENSMUSP00000126108 | ENSMUSP00000039653 | Activin receptor type-2B; Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c). Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to [...] | Nodal; Essential for mesoderm formation and axial patterning during embryonic development; Belongs to the TGF-beta family. | 0.972 |
Acvr2b | Zic3 | ENSMUSP00000126108 | ENSMUSP00000085999 | Activin receptor type-2B; Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c). Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to [...] | Zinc finger protein ZIC 3; Acts as transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC- 3'; Belongs to the GLI C2H2-type zinc-finger protein family. | 0.666 |
Cfc1 | Acvr2b | ENSMUSP00000027298 | ENSMUSP00000126108 | Cryptic protein; Nodal coreceptor involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. | Activin receptor type-2B; Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c). Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to [...] | 0.900 |
Cfc1 | Creld1 | ENSMUSP00000027298 | ENSMUSP00000032422 | Cryptic protein; Nodal coreceptor involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. | Protein disulfide isomerase Creld1; Protein disulfide isomerase (By similarity). Promotes the localization of acetylcholine receptors (AChRs) to the plasma membrane ; Belongs to the CRELD family. | 0.621 |
Cfc1 | Dnaic1 | ENSMUSP00000027298 | ENSMUSP00000100028 | Cryptic protein; Nodal coreceptor involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. | Dynein intermediate chain 1, axonemal; Part of the dynein complex of respiratory cilia. | 0.452 |
Cfc1 | Gdf1 | ENSMUSP00000027298 | ENSMUSP00000146749 | Cryptic protein; Nodal coreceptor involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. | Growth differentiation factor 1. | 0.713 |
Cfc1 | Nkx2-5 | ENSMUSP00000027298 | ENSMUSP00000015723 | Cryptic protein; Nodal coreceptor involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. | Homeobox protein Nkx-2.5; Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4. Binds to the core DNA motif of NPPA promoter. It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B. Together with PBX1, it is required for spleen development through a mechanism that involves CDKN2B repression. | 0.524 |
Cfc1 | Nodal | ENSMUSP00000027298 | ENSMUSP00000039653 | Cryptic protein; Nodal coreceptor involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. | Nodal; Essential for mesoderm formation and axial patterning during embryonic development; Belongs to the TGF-beta family. | 0.853 |
Cfc1 | Zic3 | ENSMUSP00000027298 | ENSMUSP00000085999 | Cryptic protein; Nodal coreceptor involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. | Zinc finger protein ZIC 3; Acts as transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC- 3'; Belongs to the GLI C2H2-type zinc-finger protein family. | 0.733 |
Creld1 | Acvr2b | ENSMUSP00000032422 | ENSMUSP00000126108 | Protein disulfide isomerase Creld1; Protein disulfide isomerase (By similarity). Promotes the localization of acetylcholine receptors (AChRs) to the plasma membrane ; Belongs to the CRELD family. | Activin receptor type-2B; Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c). Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to [...] | 0.451 |
Creld1 | Cfc1 | ENSMUSP00000032422 | ENSMUSP00000027298 | Protein disulfide isomerase Creld1; Protein disulfide isomerase (By similarity). Promotes the localization of acetylcholine receptors (AChRs) to the plasma membrane ; Belongs to the CRELD family. | Cryptic protein; Nodal coreceptor involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. | 0.621 |
Creld1 | Dnaic1 | ENSMUSP00000032422 | ENSMUSP00000100028 | Protein disulfide isomerase Creld1; Protein disulfide isomerase (By similarity). Promotes the localization of acetylcholine receptors (AChRs) to the plasma membrane ; Belongs to the CRELD family. | Dynein intermediate chain 1, axonemal; Part of the dynein complex of respiratory cilia. | 0.463 |
Creld1 | Gdf1 | ENSMUSP00000032422 | ENSMUSP00000146749 | Protein disulfide isomerase Creld1; Protein disulfide isomerase (By similarity). Promotes the localization of acetylcholine receptors (AChRs) to the plasma membrane ; Belongs to the CRELD family. | Growth differentiation factor 1. | 0.486 |
Creld1 | Gipc2 | ENSMUSP00000032422 | ENSMUSP00000037328 | Protein disulfide isomerase Creld1; Protein disulfide isomerase (By similarity). Promotes the localization of acetylcholine receptors (AChRs) to the plasma membrane ; Belongs to the CRELD family. | PDZ domain-containing protein GIPC2; Belongs to the GIPC family. | 0.495 |
Creld1 | Mycbp | ENSMUSP00000032422 | ENSMUSP00000030400 | Protein disulfide isomerase Creld1; Protein disulfide isomerase (By similarity). Promotes the localization of acetylcholine receptors (AChRs) to the plasma membrane ; Belongs to the CRELD family. | c-Myc-binding protein; May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC (By similarity). Belongs to the AMY1 family. | 0.451 |
Creld1 | Nkx2-5 | ENSMUSP00000032422 | ENSMUSP00000015723 | Protein disulfide isomerase Creld1; Protein disulfide isomerase (By similarity). Promotes the localization of acetylcholine receptors (AChRs) to the plasma membrane ; Belongs to the CRELD family. | Homeobox protein Nkx-2.5; Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4. Binds to the core DNA motif of NPPA promoter. It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B. Together with PBX1, it is required for spleen development through a mechanism that involves CDKN2B repression. | 0.479 |
Creld1 | Nodal | ENSMUSP00000032422 | ENSMUSP00000039653 | Protein disulfide isomerase Creld1; Protein disulfide isomerase (By similarity). Promotes the localization of acetylcholine receptors (AChRs) to the plasma membrane ; Belongs to the CRELD family. | Nodal; Essential for mesoderm formation and axial patterning during embryonic development; Belongs to the TGF-beta family. | 0.461 |