node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cd48 | Klrb1b | ENSMUSP00000064241 | ENSMUSP00000032472 | CD48 antigen; Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. | Killer cell lectin-like receptor subfamily B member 1B allele B; Receptor for CLEC2D/OCIL. Ligand-binding contributes to inhibition of cytotoxic natural killer (NK) cells. May mediate MHC class I-independent 'missing-self' recognition of allografts, tumor cells and virus-infected cells. | 0.532 |
Cd48 | Lck | ENSMUSP00000064241 | ENSMUSP00000125777 | CD48 antigen; Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. | Proto-oncogene tyrosine-protein kinase LCK; Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T- cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen- bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules, respectively, thereby recruiting the associa [...] | 0.945 |
Clec2d | Klrb1b | ENSMUSP00000032260 | ENSMUSP00000032472 | C-type lectin domain family 2 member D; Receptor for KLRB1B that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Binds high molecular weight sulfated glycosaminoglycans. | Killer cell lectin-like receptor subfamily B member 1B allele B; Receptor for CLEC2D/OCIL. Ligand-binding contributes to inhibition of cytotoxic natural killer (NK) cells. May mediate MHC class I-independent 'missing-self' recognition of allografts, tumor cells and virus-infected cells. | 0.996 |
Clec2f | Klrb1b | ENSMUSP00000158978 | ENSMUSP00000032472 | C-type lectin domain family 2 member F. | Killer cell lectin-like receptor subfamily B member 1B allele B; Receptor for CLEC2D/OCIL. Ligand-binding contributes to inhibition of cytotoxic natural killer (NK) cells. May mediate MHC class I-independent 'missing-self' recognition of allografts, tumor cells and virus-infected cells. | 0.524 |
Clec2g | Klrb1b | ENSMUSP00000000254 | ENSMUSP00000032472 | C-type lectin domain family 2 member G; Inhibits osteoclast formation. | Killer cell lectin-like receptor subfamily B member 1B allele B; Receptor for CLEC2D/OCIL. Ligand-binding contributes to inhibition of cytotoxic natural killer (NK) cells. May mediate MHC class I-independent 'missing-self' recognition of allografts, tumor cells and virus-infected cells. | 0.533 |
Klrb1b | Cd48 | ENSMUSP00000032472 | ENSMUSP00000064241 | Killer cell lectin-like receptor subfamily B member 1B allele B; Receptor for CLEC2D/OCIL. Ligand-binding contributes to inhibition of cytotoxic natural killer (NK) cells. May mediate MHC class I-independent 'missing-self' recognition of allografts, tumor cells and virus-infected cells. | CD48 antigen; Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. | 0.532 |
Klrb1b | Clec2d | ENSMUSP00000032472 | ENSMUSP00000032260 | Killer cell lectin-like receptor subfamily B member 1B allele B; Receptor for CLEC2D/OCIL. Ligand-binding contributes to inhibition of cytotoxic natural killer (NK) cells. May mediate MHC class I-independent 'missing-self' recognition of allografts, tumor cells and virus-infected cells. | C-type lectin domain family 2 member D; Receptor for KLRB1B that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Binds high molecular weight sulfated glycosaminoglycans. | 0.996 |
Klrb1b | Clec2f | ENSMUSP00000032472 | ENSMUSP00000158978 | Killer cell lectin-like receptor subfamily B member 1B allele B; Receptor for CLEC2D/OCIL. Ligand-binding contributes to inhibition of cytotoxic natural killer (NK) cells. May mediate MHC class I-independent 'missing-self' recognition of allografts, tumor cells and virus-infected cells. | C-type lectin domain family 2 member F. | 0.524 |
Klrb1b | Clec2g | ENSMUSP00000032472 | ENSMUSP00000000254 | Killer cell lectin-like receptor subfamily B member 1B allele B; Receptor for CLEC2D/OCIL. Ligand-binding contributes to inhibition of cytotoxic natural killer (NK) cells. May mediate MHC class I-independent 'missing-self' recognition of allografts, tumor cells and virus-infected cells. | C-type lectin domain family 2 member G; Inhibits osteoclast formation. | 0.533 |
Klrb1b | Lck | ENSMUSP00000032472 | ENSMUSP00000125777 | Killer cell lectin-like receptor subfamily B member 1B allele B; Receptor for CLEC2D/OCIL. Ligand-binding contributes to inhibition of cytotoxic natural killer (NK) cells. May mediate MHC class I-independent 'missing-self' recognition of allografts, tumor cells and virus-infected cells. | Proto-oncogene tyrosine-protein kinase LCK; Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T- cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen- bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules, respectively, thereby recruiting the associa [...] | 0.439 |
Lck | Cd48 | ENSMUSP00000125777 | ENSMUSP00000064241 | Proto-oncogene tyrosine-protein kinase LCK; Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T- cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen- bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules, respectively, thereby recruiting the associa [...] | CD48 antigen; Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. | 0.945 |
Lck | Klrb1b | ENSMUSP00000125777 | ENSMUSP00000032472 | Proto-oncogene tyrosine-protein kinase LCK; Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T- cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen- bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules, respectively, thereby recruiting the associa [...] | Killer cell lectin-like receptor subfamily B member 1B allele B; Receptor for CLEC2D/OCIL. Ligand-binding contributes to inhibition of cytotoxic natural killer (NK) cells. May mediate MHC class I-independent 'missing-self' recognition of allografts, tumor cells and virus-infected cells. | 0.439 |