STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hbb-yHemoglobin subunit epsilon-Y2; Hemoglobin epsilon chain is a beta-type chain found in early embryos; Belongs to the globin family. (147 aa)    
Predicted Functional Partners:
Hba-x
Hemoglobin subunit zeta; The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin; Belongs to the globin family.
  
0.988
Hbb-bh1
Hemoglobin subunit beta-H1; This is an embryonic beta-type chain.
  
0.955
Hba-a2
Hemoglobin subunit alpha; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family.
   
0.837
Hbq1b
Hemoglobin, theta 1B; Belongs to the globin family.
  
0.822
Hbq1a
Hemoglobin, theta 1A; Belongs to the globin family.
  
0.819
Hba-a1
Hemoglobin alpha, adult chain 1.
   
0.788
Hbb-bt
Hemoglobin, beta adult t chain.
  
 
0.773
Hbb-bs
Hemoglobin subunit beta-1; Involved in oxygen transport from the lung to the various peripheral tissues.
  
 
0.769
Hbb-bh2
Predicted gene, EG436003; Belongs to the globin family.
  
 
0.768
Gata1
Erythroid transcription factor; Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS (By similarity).
   
  
 0.593
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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