node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ankrd35 | Dctn2 | ENSMUSP00000047244 | ENSMUSP00000026479 | Ankyrin repeat domain 35. | Dynactin subunit 2; Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development; Belongs to the dynactin subunit 2 family. | 0.561 |
Ankrd35 | Phldb1 | ENSMUSP00000047244 | ENSMUSP00000034611 | Ankyrin repeat domain 35. | Pleckstrin homology-like domain family B member 1. | 0.560 |
Arcn1 | Phldb1 | ENSMUSP00000034607 | ENSMUSP00000034611 | Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also inf [...] | Pleckstrin homology-like domain family B member 1. | 0.450 |
Cobll1 | Phldb1 | ENSMUSP00000099787 | ENSMUSP00000034611 | Cordon-bleu protein-like 1. | Pleckstrin homology-like domain family B member 1. | 0.426 |
Dctn2 | Ankrd35 | ENSMUSP00000026479 | ENSMUSP00000047244 | Dynactin subunit 2; Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development; Belongs to the dynactin subunit 2 family. | Ankyrin repeat domain 35. | 0.561 |
Dctn2 | Phldb1 | ENSMUSP00000026479 | ENSMUSP00000034611 | Dynactin subunit 2; Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development; Belongs to the dynactin subunit 2 family. | Pleckstrin homology-like domain family B member 1. | 0.474 |
Gm17657 | Phldb1 | ENSMUSP00000157004 | ENSMUSP00000034611 | Predicted gene, 17657. | Pleckstrin homology-like domain family B member 1. | 0.423 |
Phldb1 | Ankrd35 | ENSMUSP00000034611 | ENSMUSP00000047244 | Pleckstrin homology-like domain family B member 1. | Ankyrin repeat domain 35. | 0.560 |
Phldb1 | Arcn1 | ENSMUSP00000034611 | ENSMUSP00000034607 | Pleckstrin homology-like domain family B member 1. | Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also inf [...] | 0.450 |
Phldb1 | Cobll1 | ENSMUSP00000034611 | ENSMUSP00000099787 | Pleckstrin homology-like domain family B member 1. | Cordon-bleu protein-like 1. | 0.426 |
Phldb1 | Dctn2 | ENSMUSP00000034611 | ENSMUSP00000026479 | Pleckstrin homology-like domain family B member 1. | Dynactin subunit 2; Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development; Belongs to the dynactin subunit 2 family. | 0.474 |
Phldb1 | Gm17657 | ENSMUSP00000034611 | ENSMUSP00000157004 | Pleckstrin homology-like domain family B member 1. | Predicted gene, 17657. | 0.423 |
Phldb1 | Rtel1 | ENSMUSP00000034611 | ENSMUSP00000053120 | Pleckstrin homology-like domain family B member 1. | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] | 0.615 |
Phldb1 | Treh | ENSMUSP00000034611 | ENSMUSP00000034609 | Pleckstrin homology-like domain family B member 1. | Trehalase; Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose; Belongs to the glycosyl hydrolase 37 family. | 0.527 |
Phldb1 | Wdtc1 | ENSMUSP00000034611 | ENSMUSP00000040647 | Pleckstrin homology-like domain family B member 1. | WD and tetratricopeptide repeats protein 1; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. | 0.429 |
Rtel1 | Phldb1 | ENSMUSP00000053120 | ENSMUSP00000034611 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] | Pleckstrin homology-like domain family B member 1. | 0.615 |
Treh | Phldb1 | ENSMUSP00000034609 | ENSMUSP00000034611 | Trehalase; Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose; Belongs to the glycosyl hydrolase 37 family. | Pleckstrin homology-like domain family B member 1. | 0.527 |
Wdtc1 | Phldb1 | ENSMUSP00000040647 | ENSMUSP00000034611 | WD and tetratricopeptide repeats protein 1; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. | Pleckstrin homology-like domain family B member 1. | 0.429 |