node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ccdc115 | Mrpl51 | ENSMUSP00000042918 | ENSMUSP00000032485 | Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)- ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation (By similarity). May be involved in Golgi homeostasis (By similarity). | 39S ribosomal protein L51, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL51 family. | 0.442 |
Ccdc115 | Ss18l2 | ENSMUSP00000042918 | ENSMUSP00000035113 | Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)- ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation (By similarity). May be involved in Golgi homeostasis (By similarity). | SS18-like protein 2; Belongs to the SS18 family. | 0.433 |
Gpalpp1 | Myg1 | ENSMUSP00000022585 | ENSMUSP00000109312 | GPALPP motifs-containing protein 1. | UPF0160 protein MYG1, mitochondrial. | 0.651 |
Gpalpp1 | Ss18l2 | ENSMUSP00000022585 | ENSMUSP00000035113 | GPALPP motifs-containing protein 1. | SS18-like protein 2; Belongs to the SS18 family. | 0.515 |
Gpalpp1 | Xrra1 | ENSMUSP00000022585 | ENSMUSP00000035929 | GPALPP motifs-containing protein 1. | X-ray radiation resistance-associated protein 1; May be involved in the response of cells to X-ray radiation. | 0.611 |
Gpalpp1 | Zscan26 | ENSMUSP00000022585 | ENSMUSP00000106111 | GPALPP motifs-containing protein 1. | Zinc finger and SCAN domain-containing protein 26; May be involved in transcriptional regulation. | 0.564 |
Mlf1 | Ss18l2 | ENSMUSP00000058596 | ENSMUSP00000035113 | Myeloid leukemia factor 1; Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus. | SS18-like protein 2; Belongs to the SS18 family. | 0.430 |
Mrpl51 | Ccdc115 | ENSMUSP00000032485 | ENSMUSP00000042918 | 39S ribosomal protein L51, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL51 family. | Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)- ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation (By similarity). May be involved in Golgi homeostasis (By similarity). | 0.442 |
Mrpl51 | Ndufa2 | ENSMUSP00000032485 | ENSMUSP00000014438 | 39S ribosomal protein L51, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL51 family. | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.513 |
Mrpl51 | Ss18l2 | ENSMUSP00000032485 | ENSMUSP00000035113 | 39S ribosomal protein L51, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL51 family. | SS18-like protein 2; Belongs to the SS18 family. | 0.490 |
Mrpl51 | Timm8b | ENSMUSP00000032485 | ENSMUSP00000039335 | 39S ribosomal protein L51, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL51 family. | Mitochondrial import inner membrane translocase subunit Tim8 B; Probable mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family. | 0.561 |
Myg1 | Gpalpp1 | ENSMUSP00000109312 | ENSMUSP00000022585 | UPF0160 protein MYG1, mitochondrial. | GPALPP motifs-containing protein 1. | 0.651 |
Myg1 | Ss18l2 | ENSMUSP00000109312 | ENSMUSP00000035113 | UPF0160 protein MYG1, mitochondrial. | SS18-like protein 2; Belongs to the SS18 family. | 0.432 |
Myg1 | Xrra1 | ENSMUSP00000109312 | ENSMUSP00000035929 | UPF0160 protein MYG1, mitochondrial. | X-ray radiation resistance-associated protein 1; May be involved in the response of cells to X-ray radiation. | 0.586 |
Myg1 | Zscan26 | ENSMUSP00000109312 | ENSMUSP00000106111 | UPF0160 protein MYG1, mitochondrial. | Zinc finger and SCAN domain-containing protein 26; May be involved in transcriptional regulation. | 0.487 |
Ndufa2 | Mrpl51 | ENSMUSP00000014438 | ENSMUSP00000032485 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 39S ribosomal protein L51, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL51 family. | 0.513 |
Ndufa2 | Ss18l2 | ENSMUSP00000014438 | ENSMUSP00000035113 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | SS18-like protein 2; Belongs to the SS18 family. | 0.511 |
Ndufa2 | Timm8b | ENSMUSP00000014438 | ENSMUSP00000039335 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | Mitochondrial import inner membrane translocase subunit Tim8 B; Probable mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family. | 0.758 |
Smarce1 | Ss18l2 | ENSMUSP00000099422 | ENSMUSP00000035113 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). Du [...] | SS18-like protein 2; Belongs to the SS18 family. | 0.571 |
Ss18l2 | Ccdc115 | ENSMUSP00000035113 | ENSMUSP00000042918 | SS18-like protein 2; Belongs to the SS18 family. | Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)- ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation (By similarity). May be involved in Golgi homeostasis (By similarity). | 0.433 |