STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Zbed4Zinc finger BED domain-containing protein 4. (1168 aa)    
Predicted Functional Partners:
Fam193a
Protein FAM193A; Belongs to the FAM193 family.
   
  
 0.601
Tbc1d22a
TBC1 domain family member 22A; May act as a GTPase-activating protein for Rab family protein(s).
   
  
 0.550
Ammecr1
AMME syndrome candidate gene 1 protein homolog.
   
  
 0.505
Brd1
Bromodomain-containing 1.
   
  
 0.490
Lypd5
Ly6/PLAUR domain-containing protein 5.
      
 0.464
Phf21b
PHD finger protein 21B.
   
 
 0.442
Eef1akmt1
EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
      
 0.438
Zfyve21
Zinc finger FYVE domain-containing protein 21; Plays a role in cell adhesion, and thereby in cell motility which requires repeated formation and disassembly of focal adhesions. Regulates microtubule-induced PTK2/FAK1 dephosphorylation, an event important for focal adhesion disassembly, as well as integrin beta- 1/ITGB1 cell surface expression (By similarity).
      
 0.416
Asphd1
Aspartate beta-hydroxylase domain-containing protein 1; Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
      
 0.415
Phyhipl
Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system. Belongs to the PHYHIP family.
   
  
 0.409
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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