node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bglap | Bglap2 | ENSMUSP00000075425 | ENSMUSP00000096555 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Osteocalcin-2; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | 0.980 |
Bglap | Bglap3 | ENSMUSP00000075425 | ENSMUSP00000103166 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Osteocalcin-related protein; Binds strongly to apatite and calcium. Belongs to the osteocalcin/matrix Gla protein family. | 0.901 |
Bglap | Bmp2 | ENSMUSP00000075425 | ENSMUSP00000028836 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Bone morphogenetic protein 2; Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3- EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4. Belongs to the TGF-beta family. | 0.826 |
Bglap | Car10 | ENSMUSP00000075425 | ENSMUSP00000103495 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Carbonic anhydrase-related protein 10; Does not have a catalytic activity. | 0.516 |
Bglap | Mgp | ENSMUSP00000075425 | ENSMUSP00000032342 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Matrix Gla protein; Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation. | 0.867 |
Bglap | Spp1 | ENSMUSP00000075425 | ENSMUSP00000084043 | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Osteopontin; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction; Belongs to the osteopontin family. | 0.982 |
Bglap2 | Bglap | ENSMUSP00000096555 | ENSMUSP00000075425 | Osteocalcin-2; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | 0.980 |
Bglap2 | Bglap3 | ENSMUSP00000096555 | ENSMUSP00000103166 | Osteocalcin-2; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Osteocalcin-related protein; Binds strongly to apatite and calcium. Belongs to the osteocalcin/matrix Gla protein family. | 0.901 |
Bglap2 | Bmp2 | ENSMUSP00000096555 | ENSMUSP00000028836 | Osteocalcin-2; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Bone morphogenetic protein 2; Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3- EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4. Belongs to the TGF-beta family. | 0.826 |
Bglap2 | Car10 | ENSMUSP00000096555 | ENSMUSP00000103495 | Osteocalcin-2; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Carbonic anhydrase-related protein 10; Does not have a catalytic activity. | 0.513 |
Bglap2 | Mgp | ENSMUSP00000096555 | ENSMUSP00000032342 | Osteocalcin-2; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Matrix Gla protein; Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation. | 0.867 |
Bglap2 | Spp1 | ENSMUSP00000096555 | ENSMUSP00000084043 | Osteocalcin-2; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | Osteopontin; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction; Belongs to the osteopontin family. | 0.983 |
Bglap3 | Bglap | ENSMUSP00000103166 | ENSMUSP00000075425 | Osteocalcin-related protein; Binds strongly to apatite and calcium. Belongs to the osteocalcin/matrix Gla protein family. | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | 0.901 |
Bglap3 | Bglap2 | ENSMUSP00000103166 | ENSMUSP00000096555 | Osteocalcin-related protein; Binds strongly to apatite and calcium. Belongs to the osteocalcin/matrix Gla protein family. | Osteocalcin-2; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | 0.901 |
Bglap3 | Bmp2 | ENSMUSP00000103166 | ENSMUSP00000028836 | Osteocalcin-related protein; Binds strongly to apatite and calcium. Belongs to the osteocalcin/matrix Gla protein family. | Bone morphogenetic protein 2; Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3- EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4. Belongs to the TGF-beta family. | 0.826 |
Bglap3 | Car10 | ENSMUSP00000103166 | ENSMUSP00000103495 | Osteocalcin-related protein; Binds strongly to apatite and calcium. Belongs to the osteocalcin/matrix Gla protein family. | Carbonic anhydrase-related protein 10; Does not have a catalytic activity. | 0.510 |
Bglap3 | Mgp | ENSMUSP00000103166 | ENSMUSP00000032342 | Osteocalcin-related protein; Binds strongly to apatite and calcium. Belongs to the osteocalcin/matrix Gla protein family. | Matrix Gla protein; Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation. | 0.866 |
Bglap3 | Spp1 | ENSMUSP00000103166 | ENSMUSP00000084043 | Osteocalcin-related protein; Binds strongly to apatite and calcium. Belongs to the osteocalcin/matrix Gla protein family. | Osteopontin; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction; Belongs to the osteopontin family. | 0.982 |
Bmp2 | Bglap | ENSMUSP00000028836 | ENSMUSP00000075425 | Bone morphogenetic protein 2; Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3- EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4. Belongs to the TGF-beta family. | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | 0.826 |
Bmp2 | Bglap2 | ENSMUSP00000028836 | ENSMUSP00000096555 | Bone morphogenetic protein 2; Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3- EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4. Belongs to the TGF-beta family. | Osteocalcin-2; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium; Belongs to the osteocalcin/matrix Gla protein family. | 0.826 |