node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Acsm3 | Cyp2j13 | ENSMUSP00000102138 | ENSMUSP00000030305 | Acyl-coenzyme A synthetase ACSM3, mitochondrial; Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism. Capable of activating medium-chain fatty acids with a preference for isobutyrate among fatty acids with 2-6 carbon atoms. Belongs to the ATP-dependent AMP-binding enzyme family. | Cytochrome P450, family 2, subfamily j, polypeptide 13; Belongs to the cytochrome P450 family. | 0.687 |
Acsm3 | Slc22a30 | ENSMUSP00000102138 | ENSMUSP00000093988 | Acyl-coenzyme A synthetase ACSM3, mitochondrial; Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism. Capable of activating medium-chain fatty acids with a preference for isobutyrate among fatty acids with 2-6 carbon atoms. Belongs to the ATP-dependent AMP-binding enzyme family. | Solute carrier family 22, member 30. | 0.699 |
Acsm3 | Slc7a13 | ENSMUSP00000102138 | ENSMUSP00000036228 | Acyl-coenzyme A synthetase ACSM3, mitochondrial; Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism. Capable of activating medium-chain fatty acids with a preference for isobutyrate among fatty acids with 2-6 carbon atoms. Belongs to the ATP-dependent AMP-binding enzyme family. | Solute carrier family 7 member 13; Mediates the transport L-aspartate and L-glutamate in a sodium-independent manner. | 0.715 |
Cyp2j13 | Acsm3 | ENSMUSP00000030305 | ENSMUSP00000102138 | Cytochrome P450, family 2, subfamily j, polypeptide 13; Belongs to the cytochrome P450 family. | Acyl-coenzyme A synthetase ACSM3, mitochondrial; Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism. Capable of activating medium-chain fatty acids with a preference for isobutyrate among fatty acids with 2-6 carbon atoms. Belongs to the ATP-dependent AMP-binding enzyme family. | 0.687 |
Cyp2j13 | Slc22a30 | ENSMUSP00000030305 | ENSMUSP00000093988 | Cytochrome P450, family 2, subfamily j, polypeptide 13; Belongs to the cytochrome P450 family. | Solute carrier family 22, member 30. | 0.746 |
Cyp2j13 | Slc7a13 | ENSMUSP00000030305 | ENSMUSP00000036228 | Cytochrome P450, family 2, subfamily j, polypeptide 13; Belongs to the cytochrome P450 family. | Solute carrier family 7 member 13; Mediates the transport L-aspartate and L-glutamate in a sodium-independent manner. | 0.916 |
Cyp2j13 | Slco1a1 | ENSMUSP00000030305 | ENSMUSP00000037022 | Cytochrome P450, family 2, subfamily j, polypeptide 13; Belongs to the cytochrome P450 family. | Solute carrier organic anion transporter family member 1A1; Mediates the Na(+)-independent transport of organic anions such as taurocholate, prostaglandin E2 (PGE2), dehydroepiandrosterone sulfate (DHEAS), 17-beta-glucuronosyl estradiol, estrone-3-sulfate, sulfobromophthalein (BSP), ouabain and gadoxetate; Belongs to the organo anion transporter (TC 2.A.60) family. | 0.402 |
Cyp2j13 | Ugt2b37 | ENSMUSP00000030305 | ENSMUSP00000075255 | Cytochrome P450, family 2, subfamily j, polypeptide 13; Belongs to the cytochrome P450 family. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.521 |
Slc22a22 | Slc7a13 | ENSMUSP00000105825 | ENSMUSP00000036228 | Solute carrier family 22 member 22; Sodium-independent organic anion transporter which exhibits high specificity for a subset of prostaglandins including prostaglandin E2 (PGE2), prostaglandin E1 (PGE1), prostaglandin F2-alpha (PGF2-alpha) and prostaglandin D2 (PGD2); Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. | Solute carrier family 7 member 13; Mediates the transport L-aspartate and L-glutamate in a sodium-independent manner. | 0.651 |
Slc22a28 | Slc7a13 | ENSMUSP00000067114 | ENSMUSP00000036228 | Solute carrier family 22, member 28. | Solute carrier family 7 member 13; Mediates the transport L-aspartate and L-glutamate in a sodium-independent manner. | 0.547 |
Slc22a28 | Slco1a1 | ENSMUSP00000067114 | ENSMUSP00000037022 | Solute carrier family 22, member 28. | Solute carrier organic anion transporter family member 1A1; Mediates the Na(+)-independent transport of organic anions such as taurocholate, prostaglandin E2 (PGE2), dehydroepiandrosterone sulfate (DHEAS), 17-beta-glucuronosyl estradiol, estrone-3-sulfate, sulfobromophthalein (BSP), ouabain and gadoxetate; Belongs to the organo anion transporter (TC 2.A.60) family. | 0.529 |
Slc22a30 | Acsm3 | ENSMUSP00000093988 | ENSMUSP00000102138 | Solute carrier family 22, member 30. | Acyl-coenzyme A synthetase ACSM3, mitochondrial; Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism. Capable of activating medium-chain fatty acids with a preference for isobutyrate among fatty acids with 2-6 carbon atoms. Belongs to the ATP-dependent AMP-binding enzyme family. | 0.699 |
Slc22a30 | Cyp2j13 | ENSMUSP00000093988 | ENSMUSP00000030305 | Solute carrier family 22, member 30. | Cytochrome P450, family 2, subfamily j, polypeptide 13; Belongs to the cytochrome P450 family. | 0.746 |
Slc22a30 | Slc7a13 | ENSMUSP00000093988 | ENSMUSP00000036228 | Solute carrier family 22, member 30. | Solute carrier family 7 member 13; Mediates the transport L-aspartate and L-glutamate in a sodium-independent manner. | 0.773 |
Slc22a30 | Slco1a1 | ENSMUSP00000093988 | ENSMUSP00000037022 | Solute carrier family 22, member 30. | Solute carrier organic anion transporter family member 1A1; Mediates the Na(+)-independent transport of organic anions such as taurocholate, prostaglandin E2 (PGE2), dehydroepiandrosterone sulfate (DHEAS), 17-beta-glucuronosyl estradiol, estrone-3-sulfate, sulfobromophthalein (BSP), ouabain and gadoxetate; Belongs to the organo anion transporter (TC 2.A.60) family. | 0.864 |
Slc22a30 | Ugt2b37 | ENSMUSP00000093988 | ENSMUSP00000075255 | Solute carrier family 22, member 30. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.613 |
Slc3a1 | Slc3a2 | ENSMUSP00000024944 | ENSMUSP00000130194 | Neutral and basic amino acid transport protein rBAT; Involved in the high-affinity sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). May function as an activator of SLC7A9 and be involved in the high-affinity reabsorption of cystine in the kidney proximal tubule. | 4F2 cell-surface antigen heavy chain; Component of several heterodimeric amino acid transporter complexes. The precise substrate specificity depends on the other subunit in the heterodimer. The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptophan. The complexes with SLC7A6 and SLC7A7 mediate uptake of dibasic amino acids. The complexes function as amino acid exchangers (By similarity). Required for targeting of SLC7A5 and [...] | 0.489 |
Slc3a1 | Slc7a13 | ENSMUSP00000024944 | ENSMUSP00000036228 | Neutral and basic amino acid transport protein rBAT; Involved in the high-affinity sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). May function as an activator of SLC7A9 and be involved in the high-affinity reabsorption of cystine in the kidney proximal tubule. | Solute carrier family 7 member 13; Mediates the transport L-aspartate and L-glutamate in a sodium-independent manner. | 0.929 |
Slc3a1 | Slc7a3 | ENSMUSP00000024944 | ENSMUSP00000109339 | Neutral and basic amino acid transport protein rBAT; Involved in the high-affinity sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). May function as an activator of SLC7A9 and be involved in the high-affinity reabsorption of cystine in the kidney proximal tubule. | Cationic amino acid transporter 3; Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner. | 0.655 |
Slc3a2 | Slc3a1 | ENSMUSP00000130194 | ENSMUSP00000024944 | 4F2 cell-surface antigen heavy chain; Component of several heterodimeric amino acid transporter complexes. The precise substrate specificity depends on the other subunit in the heterodimer. The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptophan. The complexes with SLC7A6 and SLC7A7 mediate uptake of dibasic amino acids. The complexes function as amino acid exchangers (By similarity). Required for targeting of SLC7A5 and [...] | Neutral and basic amino acid transport protein rBAT; Involved in the high-affinity sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). May function as an activator of SLC7A9 and be involved in the high-affinity reabsorption of cystine in the kidney proximal tubule. | 0.489 |