node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Adck1 | Cspp1 | ENSMUSP00000152821 | ENSMUSP00000068804 | AarF domain-containing protein kinase 1; Appears to be essential for maintaining mitochondrial cristae formation and mitochondrial function by acting via YME1L1 in a kinase- independent manner to regulate essential mitochondrial structural proteins OPA1 and IMMT (By similarity). The action of this enzyme is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) (Probable). | Centrosome and spindle pole associated protein 1; May play a role in cell-cycle-dependent microtubule organization. | 0.519 |
Adck1 | Hdhd3 | ENSMUSP00000152821 | ENSMUSP00000036337 | AarF domain-containing protein kinase 1; Appears to be essential for maintaining mitochondrial cristae formation and mitochondrial function by acting via YME1L1 in a kinase- independent manner to regulate essential mitochondrial structural proteins OPA1 and IMMT (By similarity). The action of this enzyme is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) (Probable). | Haloacid dehalogenase-like hydrolase domain-containing protein 3; Belongs to the HAD-like hydrolase superfamily. | 0.468 |
Alad | Hdhd3 | ENSMUSP00000103068 | ENSMUSP00000036337 | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | Haloacid dehalogenase-like hydrolase domain-containing protein 3; Belongs to the HAD-like hydrolase superfamily. | 0.480 |
Bspry | Cspp1 | ENSMUSP00000030088 | ENSMUSP00000068804 | B box and SPRY domain-containing protein; May regulate epithelial calcium transport by inhibiting TRPV5 activity. | Centrosome and spindle pole associated protein 1; May play a role in cell-cycle-dependent microtubule organization. | 0.520 |
Bspry | Hdhd3 | ENSMUSP00000030088 | ENSMUSP00000036337 | B box and SPRY domain-containing protein; May regulate epithelial calcium transport by inhibiting TRPV5 activity. | Haloacid dehalogenase-like hydrolase domain-containing protein 3; Belongs to the HAD-like hydrolase superfamily. | 0.474 |
Bspry | Nif3l1 | ENSMUSP00000030088 | ENSMUSP00000084799 | B box and SPRY domain-containing protein; May regulate epithelial calcium transport by inhibiting TRPV5 activity. | NIF3-like protein 1; May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation. | 0.522 |
Ccdc137 | Hdhd3 | ENSMUSP00000062540 | ENSMUSP00000036337 | Coiled-coil domain-containing protein 137. | Haloacid dehalogenase-like hydrolase domain-containing protein 3; Belongs to the HAD-like hydrolase superfamily. | 0.572 |
Cspp1 | Adck1 | ENSMUSP00000068804 | ENSMUSP00000152821 | Centrosome and spindle pole associated protein 1; May play a role in cell-cycle-dependent microtubule organization. | AarF domain-containing protein kinase 1; Appears to be essential for maintaining mitochondrial cristae formation and mitochondrial function by acting via YME1L1 in a kinase- independent manner to regulate essential mitochondrial structural proteins OPA1 and IMMT (By similarity). The action of this enzyme is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) (Probable). | 0.519 |
Cspp1 | Bspry | ENSMUSP00000068804 | ENSMUSP00000030088 | Centrosome and spindle pole associated protein 1; May play a role in cell-cycle-dependent microtubule organization. | B box and SPRY domain-containing protein; May regulate epithelial calcium transport by inhibiting TRPV5 activity. | 0.520 |
Cspp1 | Hdhd3 | ENSMUSP00000068804 | ENSMUSP00000036337 | Centrosome and spindle pole associated protein 1; May play a role in cell-cycle-dependent microtubule organization. | Haloacid dehalogenase-like hydrolase domain-containing protein 3; Belongs to the HAD-like hydrolase superfamily. | 0.474 |
Cspp1 | Nif3l1 | ENSMUSP00000068804 | ENSMUSP00000084799 | Centrosome and spindle pole associated protein 1; May play a role in cell-cycle-dependent microtubule organization. | NIF3-like protein 1; May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation. | 0.487 |
Fgfbp3 | Hdhd3 | ENSMUSP00000159137 | ENSMUSP00000036337 | Fibroblast growth factor-binding protein 3; Heparin-binding protein which binds to FGF2, prevents binding of FGF2 to heparin and probably inhibits immobilization of FGF2 on extracellular matrix glycosaminoglycans, allowing its release and subsequent activation of FGFR signaling which leads to increased vascular permeability; Belongs to the fibroblast growth factor-binding protein family. | Haloacid dehalogenase-like hydrolase domain-containing protein 3; Belongs to the HAD-like hydrolase superfamily. | 0.505 |
Hdhd3 | Adck1 | ENSMUSP00000036337 | ENSMUSP00000152821 | Haloacid dehalogenase-like hydrolase domain-containing protein 3; Belongs to the HAD-like hydrolase superfamily. | AarF domain-containing protein kinase 1; Appears to be essential for maintaining mitochondrial cristae formation and mitochondrial function by acting via YME1L1 in a kinase- independent manner to regulate essential mitochondrial structural proteins OPA1 and IMMT (By similarity). The action of this enzyme is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) (Probable). | 0.468 |
Hdhd3 | Alad | ENSMUSP00000036337 | ENSMUSP00000103068 | Haloacid dehalogenase-like hydrolase domain-containing protein 3; Belongs to the HAD-like hydrolase superfamily. | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | 0.480 |
Hdhd3 | Bspry | ENSMUSP00000036337 | ENSMUSP00000030088 | Haloacid dehalogenase-like hydrolase domain-containing protein 3; Belongs to the HAD-like hydrolase superfamily. | B box and SPRY domain-containing protein; May regulate epithelial calcium transport by inhibiting TRPV5 activity. | 0.474 |
Hdhd3 | Ccdc137 | ENSMUSP00000036337 | ENSMUSP00000062540 | Haloacid dehalogenase-like hydrolase domain-containing protein 3; Belongs to the HAD-like hydrolase superfamily. | Coiled-coil domain-containing protein 137. | 0.572 |
Hdhd3 | Cspp1 | ENSMUSP00000036337 | ENSMUSP00000068804 | Haloacid dehalogenase-like hydrolase domain-containing protein 3; Belongs to the HAD-like hydrolase superfamily. | Centrosome and spindle pole associated protein 1; May play a role in cell-cycle-dependent microtubule organization. | 0.474 |
Hdhd3 | Fgfbp3 | ENSMUSP00000036337 | ENSMUSP00000159137 | Haloacid dehalogenase-like hydrolase domain-containing protein 3; Belongs to the HAD-like hydrolase superfamily. | Fibroblast growth factor-binding protein 3; Heparin-binding protein which binds to FGF2, prevents binding of FGF2 to heparin and probably inhibits immobilization of FGF2 on extracellular matrix glycosaminoglycans, allowing its release and subsequent activation of FGFR signaling which leads to increased vascular permeability; Belongs to the fibroblast growth factor-binding protein family. | 0.505 |
Hdhd3 | Klhl29 | ENSMUSP00000036337 | ENSMUSP00000020958 | Haloacid dehalogenase-like hydrolase domain-containing protein 3; Belongs to the HAD-like hydrolase superfamily. | Kelch-like protein 29. | 0.505 |
Hdhd3 | Ndrg3 | ENSMUSP00000036337 | ENSMUSP00000070052 | Haloacid dehalogenase-like hydrolase domain-containing protein 3; Belongs to the HAD-like hydrolase superfamily. | Protein NDRG3; Belongs to the NDRG family. | 0.567 |