node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Slc30a1 | Slc30a2 | ENSMUSP00000042410 | ENSMUSP00000101500 | Zinc transporter 1; May be involved in zinc transport out of the cell. Lethality of knockout early in gestation suggests a role of the protein in fetal zinc acquisition and retention; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Zinc transporter 2; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | 0.451 |
Slc30a1 | Slc30a4 | ENSMUSP00000042410 | ENSMUSP00000005952 | Zinc transporter 1; May be involved in zinc transport out of the cell. Lethality of knockout early in gestation suggests a role of the protein in fetal zinc acquisition and retention; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Zinc transporter 4; Probably involved in zinc transport out of the cytoplasm, may be by sequestration into an intracellular compartment. | 0.557 |
Slc30a1 | Slc30a5 | ENSMUSP00000042410 | ENSMUSP00000065764 | Zinc transporter 1; May be involved in zinc transport out of the cell. Lethality of knockout early in gestation suggests a role of the protein in fetal zinc acquisition and retention; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Zinc transporter 5; Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP (By similarity); Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | 0.515 |
Slc30a1 | Slc30a6 | ENSMUSP00000042410 | ENSMUSP00000136503 | Zinc transporter 1; May be involved in zinc transport out of the cell. Lethality of knockout early in gestation suggests a role of the protein in fetal zinc acquisition and retention; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Zinc transporter 6; Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment. | 0.899 |
Slc30a1 | Slc30a7 | ENSMUSP00000042410 | ENSMUSP00000065254 | Zinc transporter 1; May be involved in zinc transport out of the cell. Lethality of knockout early in gestation suggests a role of the protein in fetal zinc acquisition and retention; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Zinc transporter 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity). | 0.484 |
Slc30a1 | Slc30a9 | ENSMUSP00000042410 | ENSMUSP00000124047 | Zinc transporter 1; May be involved in zinc transport out of the cell. Lethality of knockout early in gestation suggests a role of the protein in fetal zinc acquisition and retention; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Zinc transporter 9; Acts as a zinc transporter involved in intracellular zinc homeostasis (By similarity). Functions as a secondary coactivator for nuclear receptors by cooperating with p160 coactivators subtypes. Plays a role in transcriptional activation of Wnt- responsive genes ; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | 0.811 |
Slc30a1 | Slc39a1 | ENSMUSP00000042410 | ENSMUSP00000076012 | Zinc transporter 1; May be involved in zinc transport out of the cell. Lethality of knockout early in gestation suggests a role of the protein in fetal zinc acquisition and retention; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Zinc transporter ZIP1; Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body (By similarity). Belongs to the ZIP transporter (TC 2.A.5) family. | 0.882 |
Slc30a1 | Slc39a11 | ENSMUSP00000042410 | ENSMUSP00000102244 | Zinc transporter 1; May be involved in zinc transport out of the cell. Lethality of knockout early in gestation suggests a role of the protein in fetal zinc acquisition and retention; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Zinc transporter ZIP11; Functions as a cellular zinc transporter. | 0.782 |
Slc30a1 | Slc39a5 | ENSMUSP00000042410 | ENSMUSP00000131736 | Zinc transporter 1; May be involved in zinc transport out of the cell. Lethality of knockout early in gestation suggests a role of the protein in fetal zinc acquisition and retention; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Zinc transporter ZIP5; May play a role in polarized cells by carrying out serosal- to-mucosal zinc transport. Plays a role in eye development. Could regulate the BMP/TGF-beta (bone morphogenetic protein/transforming growth factor-beta) signaling pathway and modulates extracellular matrix (ECM) proteins of the sclera. Seems to play a central role in controlling organismal zinc status. | 0.769 |
Slc30a1 | Slc39a9 | ENSMUSP00000042410 | ENSMUSP00000082343 | Zinc transporter 1; May be involved in zinc transport out of the cell. Lethality of knockout early in gestation suggests a role of the protein in fetal zinc acquisition and retention; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Zinc transporter ZIP9; May act as a zinc-influx transporter; Belongs to the ZIP transporter (TC 2.A.5) family. | 0.739 |
Slc30a2 | Slc30a1 | ENSMUSP00000101500 | ENSMUSP00000042410 | Zinc transporter 2; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Zinc transporter 1; May be involved in zinc transport out of the cell. Lethality of knockout early in gestation suggests a role of the protein in fetal zinc acquisition and retention; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | 0.451 |
Slc30a2 | Slc30a5 | ENSMUSP00000101500 | ENSMUSP00000065764 | Zinc transporter 2; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Zinc transporter 5; Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP (By similarity); Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | 0.452 |
Slc30a2 | Slc30a6 | ENSMUSP00000101500 | ENSMUSP00000136503 | Zinc transporter 2; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Zinc transporter 6; Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment. | 0.850 |
Slc30a2 | Slc30a7 | ENSMUSP00000101500 | ENSMUSP00000065254 | Zinc transporter 2; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Zinc transporter 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity). | 0.482 |
Slc30a2 | Slc30a9 | ENSMUSP00000101500 | ENSMUSP00000124047 | Zinc transporter 2; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Zinc transporter 9; Acts as a zinc transporter involved in intracellular zinc homeostasis (By similarity). Functions as a secondary coactivator for nuclear receptors by cooperating with p160 coactivators subtypes. Plays a role in transcriptional activation of Wnt- responsive genes ; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | 0.792 |
Slc30a2 | Slc39a1 | ENSMUSP00000101500 | ENSMUSP00000076012 | Zinc transporter 2; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Zinc transporter ZIP1; Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body (By similarity). Belongs to the ZIP transporter (TC 2.A.5) family. | 0.728 |
Slc30a2 | Slc39a11 | ENSMUSP00000101500 | ENSMUSP00000102244 | Zinc transporter 2; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Zinc transporter ZIP11; Functions as a cellular zinc transporter. | 0.712 |
Slc30a2 | Slc39a5 | ENSMUSP00000101500 | ENSMUSP00000131736 | Zinc transporter 2; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Zinc transporter ZIP5; May play a role in polarized cells by carrying out serosal- to-mucosal zinc transport. Plays a role in eye development. Could regulate the BMP/TGF-beta (bone morphogenetic protein/transforming growth factor-beta) signaling pathway and modulates extracellular matrix (ECM) proteins of the sclera. Seems to play a central role in controlling organismal zinc status. | 0.739 |
Slc30a2 | Slc39a9 | ENSMUSP00000101500 | ENSMUSP00000082343 | Zinc transporter 2; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Zinc transporter ZIP9; May act as a zinc-influx transporter; Belongs to the ZIP transporter (TC 2.A.5) family. | 0.682 |
Slc30a4 | Slc30a1 | ENSMUSP00000005952 | ENSMUSP00000042410 | Zinc transporter 4; Probably involved in zinc transport out of the cytoplasm, may be by sequestration into an intracellular compartment. | Zinc transporter 1; May be involved in zinc transport out of the cell. Lethality of knockout early in gestation suggests a role of the protein in fetal zinc acquisition and retention; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | 0.557 |