STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gpr162Probable G-protein coupled receptor 162; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. (588 aa)    
Predicted Functional Partners:
Gpr26
G-protein coupled receptor 26; Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP (By similarity); Belongs to the G-protein coupled receptor 1 family.
   
  
 0.664
Gpr150
Probable G-protein coupled receptor 150; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.611
Gpr152
Probable G-protein coupled receptor 152; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.593
Fam162b
Protein FAM162B.
    
 
 0.570
Adgra1
Adhesion G protein-coupled receptor A1; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
   
 
 0.567
Gpr62
G-protein coupled receptor 62; Orphan G-protein coupled receptor. Constitutively activates the G(q/11)/inositol phosphate and the G(s)-alpha/cAMP signaling pathways. Has spontaneous activity for beta-arrestin recruitment (By similarity). Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (By similarity).
   
  
 0.565
Tmem221
Transmembrane protein 221.
      
 0.564
Usp32
Ubiquitin-specific peptidase 32; Belongs to the peptidase C19 family.
   
 
 0.561
Gpr139
Probable G-protein coupled receptor 139; Orphan receptor. Seems to act through a G(q/11)-mediated pathway.
   
  
 0.559
Gpr82
Probable G-protein coupled receptor 82; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.551
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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