node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Gm49336 | Nup107 | ENSMUSP00000038716 | ENSMUSP00000063590 | Nucleoporin p58/p45; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane. Belongs to the NUP58 family. | Nuclear pore complex protein Nup107; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC. Involved in nephrogenesis. | 0.976 |
Gm49336 | Nup155 | ENSMUSP00000038716 | ENSMUSP00000128819 | Nucleoporin p58/p45; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane. Belongs to the NUP58 family. | Nuclear pore complex protein Nup155; Essential component of nuclear pore complex. Could be essessential for embryogenesis. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport. Belongs to the non-repetitive/WGA-negative nucleoporin family. | 0.973 |
Gm49336 | Nup188 | ENSMUSP00000038716 | ENSMUSP00000065836 | Nucleoporin p58/p45; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane. Belongs to the NUP58 family. | Nucleoporin NUP188 homolog; May function as a component of the nuclear pore complex (NPC). | 0.971 |
Gm49336 | Nup205 | ENSMUSP00000038716 | ENSMUSP00000039656 | Nucleoporin p58/p45; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane. Belongs to the NUP58 family. | Nucleoporin 205. | 0.972 |
Gm49336 | Nup214 | ENSMUSP00000038716 | ENSMUSP00000066492 | Nucleoporin p58/p45; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane. Belongs to the NUP58 family. | Nuclear pore complex protein Nup214; Has a critical role in nucleocytoplasmic transport (By similarity). May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex. | 0.976 |
Gm49336 | Nup35 | ENSMUSP00000038716 | ENSMUSP00000028382 | Nucleoporin p58/p45; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane. Belongs to the NUP58 family. | Nucleoporin NUP35; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. May play a role in the association of MAD1 with the NPC (By similarity). | 0.980 |
Gm49336 | Nup54 | ENSMUSP00000038716 | ENSMUSP00000046540 | Nucleoporin p58/p45; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane. Belongs to the NUP58 family. | Nuclear pore complex protein Nup54; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane. | 0.999 |
Gm49336 | Nup62 | ENSMUSP00000038716 | ENSMUSP00000056785 | Nucleoporin p58/p45; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane. Belongs to the NUP58 family. | Nuclear pore glycoprotein p62; Essential component of the nuclear pore complex. The N- terminal is probably involved in nucleocytoplasmic transport. The C- terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex. Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation. It might be involved in protein recruitment to the centrosome after nuclear breakdown. Belongs to the nucleoporin NSP [...] | 0.995 |
Gm49336 | Nup93 | ENSMUSP00000038716 | ENSMUSP00000148700 | Nucleoporin p58/p45; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane. Belongs to the NUP58 family. | Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC (By similarity). During renal development, regulates podocyte migration and proliferation through SMAD4 signaling (By similarity) ; Belongs to the nucleoporin interacting component (NIC) family. | 0.989 |
Gm49336 | Ranbp2 | ENSMUSP00000038716 | ENSMUSP00000003310 | Nucleoporin p58/p45; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane. Belongs to the NUP58 family. | E3 SUMO-protein ligase RanBP2; E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Binds single- stranded RNA (in vitro). May bind DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1 (By similarity). Sumoylates PML at 'Lys-490' which is essential for the proper assembly of PML-NB. Recruits BICD2 to the nuclear envelope and cytoplasmic stacks of nuc [...] | 0.973 |
Nup107 | Gm49336 | ENSMUSP00000063590 | ENSMUSP00000038716 | Nuclear pore complex protein Nup107; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC. Involved in nephrogenesis. | Nucleoporin p58/p45; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane. Belongs to the NUP58 family. | 0.976 |
Nup107 | Nup155 | ENSMUSP00000063590 | ENSMUSP00000128819 | Nuclear pore complex protein Nup107; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC. Involved in nephrogenesis. | Nuclear pore complex protein Nup155; Essential component of nuclear pore complex. Could be essessential for embryogenesis. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport. Belongs to the non-repetitive/WGA-negative nucleoporin family. | 0.997 |
Nup107 | Nup188 | ENSMUSP00000063590 | ENSMUSP00000065836 | Nuclear pore complex protein Nup107; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC. Involved in nephrogenesis. | Nucleoporin NUP188 homolog; May function as a component of the nuclear pore complex (NPC). | 0.968 |
Nup107 | Nup205 | ENSMUSP00000063590 | ENSMUSP00000039656 | Nuclear pore complex protein Nup107; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC. Involved in nephrogenesis. | Nucleoporin 205. | 0.999 |
Nup107 | Nup214 | ENSMUSP00000063590 | ENSMUSP00000066492 | Nuclear pore complex protein Nup107; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC. Involved in nephrogenesis. | Nuclear pore complex protein Nup214; Has a critical role in nucleocytoplasmic transport (By similarity). May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex. | 0.998 |
Nup107 | Nup35 | ENSMUSP00000063590 | ENSMUSP00000028382 | Nuclear pore complex protein Nup107; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC. Involved in nephrogenesis. | Nucleoporin NUP35; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. May play a role in the association of MAD1 with the NPC (By similarity). | 0.991 |
Nup107 | Nup54 | ENSMUSP00000063590 | ENSMUSP00000046540 | Nuclear pore complex protein Nup107; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC. Involved in nephrogenesis. | Nuclear pore complex protein Nup54; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane. | 0.996 |
Nup107 | Nup62 | ENSMUSP00000063590 | ENSMUSP00000056785 | Nuclear pore complex protein Nup107; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC. Involved in nephrogenesis. | Nuclear pore glycoprotein p62; Essential component of the nuclear pore complex. The N- terminal is probably involved in nucleocytoplasmic transport. The C- terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex. Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation. It might be involved in protein recruitment to the centrosome after nuclear breakdown. Belongs to the nucleoporin NSP [...] | 0.987 |
Nup107 | Nup93 | ENSMUSP00000063590 | ENSMUSP00000148700 | Nuclear pore complex protein Nup107; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC. Involved in nephrogenesis. | Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC (By similarity). During renal development, regulates podocyte migration and proliferation through SMAD4 signaling (By similarity) ; Belongs to the nucleoporin interacting component (NIC) family. | 0.999 |
Nup107 | Ranbp2 | ENSMUSP00000063590 | ENSMUSP00000003310 | Nuclear pore complex protein Nup107; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC. Involved in nephrogenesis. | E3 SUMO-protein ligase RanBP2; E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Binds single- stranded RNA (in vitro). May bind DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1 (By similarity). Sumoylates PML at 'Lys-490' which is essential for the proper assembly of PML-NB. Recruits BICD2 to the nuclear envelope and cytoplasmic stacks of nuc [...] | 0.998 |