Smim3 protein (mouse) - STRING interaction network

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

Smim3

Small integral membrane protein 3. (60 aa)

Predicted Functional Partners:

Smim1

0.712

Rps14

0.642

Dctn4

0.604

Acsbg3

0.572

Kctd14

0.572

Spred3

0.562

Rtl8c

0.552

Rbm22

0.547

Tmem56

0.544

Tmem40

0.535

Your Current Organism:

Mus musculus

NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Acsbg3	Smim3	ENSMUSP00000025048	ENSMUSP00000039285	Acyl-CoA synthetase bubblegum family member 3.	Small integral membrane protein 3.	0.572
Dctn4	Rbm22	ENSMUSP00000025505	ENSMUSP00000025506	Dynactin subunit 4; Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.	Pre-mRNA-splicing factor RBM22; Required for pre-mRNA splicing as component of the activated spliceosome. Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses; Belongs to the SLT11 family.	0.699
Dctn4	Smim3	ENSMUSP00000025505	ENSMUSP00000039285	Dynactin subunit 4; Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.	Small integral membrane protein 3.	0.604
Kctd14	Smim3	ENSMUSP00000145558	ENSMUSP00000039285	Potassium channel tetramerisation domain-containing 14.	Small integral membrane protein 3.	0.572
Kctd14	Spred3	ENSMUSP00000145558	ENSMUSP00000046216	Potassium channel tetramerisation domain-containing 14.	Sprouty-related, EVH1 domain-containing protein 3; Tyrosine kinase substrate that inhibits growth-factor- mediated activation of MAP kinase.	0.455
Rbm22	Dctn4	ENSMUSP00000025506	ENSMUSP00000025505	Pre-mRNA-splicing factor RBM22; Required for pre-mRNA splicing as component of the activated spliceosome. Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses; Belongs to the SLT11 family.	Dynactin subunit 4; Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.	0.699
Rbm22	Smim3	ENSMUSP00000025506	ENSMUSP00000039285	Pre-mRNA-splicing factor RBM22; Required for pre-mRNA splicing as component of the activated spliceosome. Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses; Belongs to the SLT11 family.	Small integral membrane protein 3.	0.547
Rps14	Smim3	ENSMUSP00000157948	ENSMUSP00000039285	40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	Small integral membrane protein 3.	0.642
Rtl8c	Smim3	ENSMUSP00000069901	ENSMUSP00000039285	Retrotransposon Gag-like 8C.	Small integral membrane protein 3.	0.552
Rtl8c	Tmem40	ENSMUSP00000069901	ENSMUSP00000072704	Retrotransposon Gag-like 8C.	Transmembrane protein 40.	0.491
Smim1	Smim3	ENSMUSP00000138692	ENSMUSP00000039285	Small integral membrane protein 1; Regulator of red blood cell formation.	Small integral membrane protein 3.	0.712
Smim3	Acsbg3	ENSMUSP00000039285	ENSMUSP00000025048	Small integral membrane protein 3.	Acyl-CoA synthetase bubblegum family member 3.	0.572
Smim3	Dctn4	ENSMUSP00000039285	ENSMUSP00000025505	Small integral membrane protein 3.	Dynactin subunit 4; Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.	0.604
Smim3	Kctd14	ENSMUSP00000039285	ENSMUSP00000145558	Small integral membrane protein 3.	Potassium channel tetramerisation domain-containing 14.	0.572
Smim3	Rbm22	ENSMUSP00000039285	ENSMUSP00000025506	Small integral membrane protein 3.	Pre-mRNA-splicing factor RBM22; Required for pre-mRNA splicing as component of the activated spliceosome. Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses; Belongs to the SLT11 family.	0.547
Smim3	Rps14	ENSMUSP00000039285	ENSMUSP00000157948	Small integral membrane protein 3.	40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	0.642
Smim3	Rtl8c	ENSMUSP00000039285	ENSMUSP00000069901	Small integral membrane protein 3.	Retrotransposon Gag-like 8C.	0.552
Smim3	Smim1	ENSMUSP00000039285	ENSMUSP00000138692	Small integral membrane protein 3.	Small integral membrane protein 1; Regulator of red blood cell formation.	0.712
Smim3	Spred3	ENSMUSP00000039285	ENSMUSP00000046216	Small integral membrane protein 3.	Sprouty-related, EVH1 domain-containing protein 3; Tyrosine kinase substrate that inhibits growth-factor- mediated activation of MAP kinase.	0.562
Smim3	Tmem40	ENSMUSP00000039285	ENSMUSP00000072704	Small integral membrane protein 3.	Transmembrane protein 40.	0.535