STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Uroc1Urocanate hydratase. (710 aa)    
Predicted Functional Partners:
Hal
Histidine ammonia-lyase; Belongs to the PAL/histidase family.
 
 
 0.992
Amdhd1
Probable imidazolonepropionase.
  
 
 0.990
Ftcd
Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the N-terminal section; belongs to the formiminotransferase family.
  
  
 0.897
4930590J08Rik
Uncharacterized protein C3orf20 homolog.
    
 
 0.691
Txnrd3
Thioredoxin reductase 3; Displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. Catalyzes disulfide bond isomerization. Promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
      
 0.660
Agxt
Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes).
   
  
 0.611
Vmn1r40
Vomeronasal type-1 receptor 40; Putative pheromone receptor implicated in the regulation of social and reproductive behavior.
      
 0.578
Proc
Vitamin K-dependent protein C heavy chain; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family.
   
    0.554
Hpd
4-hydroxyphenylpyruvate dioxygenase; Key enzyme in the degradation of tyrosine; Belongs to the 4HPPD family.
   
    0.552
Vmn1r47
Vomeronasal type-1 receptor 47; Putative pheromone receptor implicated in the regulation of social and reproductive behavior.
      
 0.552
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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