node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
4930590J08Rik | Uroc1 | ENSMUSP00000146101 | ENSMUSP00000127114 | Uncharacterized protein C3orf20 homolog. | Urocanate hydratase. | 0.691 |
Agxt | Amdhd1 | ENSMUSP00000027491 | ENSMUSP00000016034 | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | Probable imidazolonepropionase. | 0.443 |
Agxt | Ftcd | ENSMUSP00000027491 | ENSMUSP00000001183 | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the N-terminal section; belongs to the formiminotransferase family. | 0.869 |
Agxt | Hal | ENSMUSP00000027491 | ENSMUSP00000123336 | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | Histidine ammonia-lyase; Belongs to the PAL/histidase family. | 0.599 |
Agxt | Hpd | ENSMUSP00000027491 | ENSMUSP00000031398 | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | 4-hydroxyphenylpyruvate dioxygenase; Key enzyme in the degradation of tyrosine; Belongs to the 4HPPD family. | 0.632 |
Agxt | Proc | ENSMUSP00000027491 | ENSMUSP00000157269 | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | Vitamin K-dependent protein C heavy chain; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family. | 0.428 |
Agxt | Uroc1 | ENSMUSP00000027491 | ENSMUSP00000127114 | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | Urocanate hydratase. | 0.611 |
Amdhd1 | Agxt | ENSMUSP00000016034 | ENSMUSP00000027491 | Probable imidazolonepropionase. | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | 0.443 |
Amdhd1 | Ftcd | ENSMUSP00000016034 | ENSMUSP00000001183 | Probable imidazolonepropionase. | Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the N-terminal section; belongs to the formiminotransferase family. | 0.983 |
Amdhd1 | Hal | ENSMUSP00000016034 | ENSMUSP00000123336 | Probable imidazolonepropionase. | Histidine ammonia-lyase; Belongs to the PAL/histidase family. | 0.904 |
Amdhd1 | Uroc1 | ENSMUSP00000016034 | ENSMUSP00000127114 | Probable imidazolonepropionase. | Urocanate hydratase. | 0.990 |
Ftcd | Agxt | ENSMUSP00000001183 | ENSMUSP00000027491 | Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the N-terminal section; belongs to the formiminotransferase family. | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | 0.869 |
Ftcd | Amdhd1 | ENSMUSP00000001183 | ENSMUSP00000016034 | Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the N-terminal section; belongs to the formiminotransferase family. | Probable imidazolonepropionase. | 0.983 |
Ftcd | Hal | ENSMUSP00000001183 | ENSMUSP00000123336 | Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the N-terminal section; belongs to the formiminotransferase family. | Histidine ammonia-lyase; Belongs to the PAL/histidase family. | 0.892 |
Ftcd | Hpd | ENSMUSP00000001183 | ENSMUSP00000031398 | Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the N-terminal section; belongs to the formiminotransferase family. | 4-hydroxyphenylpyruvate dioxygenase; Key enzyme in the degradation of tyrosine; Belongs to the 4HPPD family. | 0.505 |
Ftcd | Proc | ENSMUSP00000001183 | ENSMUSP00000157269 | Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the N-terminal section; belongs to the formiminotransferase family. | Vitamin K-dependent protein C heavy chain; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family. | 0.637 |
Ftcd | Uroc1 | ENSMUSP00000001183 | ENSMUSP00000127114 | Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the N-terminal section; belongs to the formiminotransferase family. | Urocanate hydratase. | 0.897 |
Hal | Agxt | ENSMUSP00000123336 | ENSMUSP00000027491 | Histidine ammonia-lyase; Belongs to the PAL/histidase family. | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | 0.599 |
Hal | Amdhd1 | ENSMUSP00000123336 | ENSMUSP00000016034 | Histidine ammonia-lyase; Belongs to the PAL/histidase family. | Probable imidazolonepropionase. | 0.904 |
Hal | Ftcd | ENSMUSP00000123336 | ENSMUSP00000001183 | Histidine ammonia-lyase; Belongs to the PAL/histidase family. | Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the N-terminal section; belongs to the formiminotransferase family. | 0.892 |