STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IqccIQ domain-containing protein C. (418 aa)    
Predicted Functional Partners:
Proser3
Proline and serine-rich protein 3.
   
 
 0.874
Fam166b
Protein FAM166B.
      
 0.793
Oacyl
O-acyltransferase like protein; Belongs to the acyltransferase 3 family.
      
 0.784
Sdf2l1
Stromal cell-derived factor 2-like protein 1.
      
 0.672
Oog3
Oogenesin-3; Belongs to the PRAME family.
      
 0.651
Zfp277
Zinc finger protein 277.
   
  
 0.641
Peli3
E3 ubiquitin-protein ligase pellino homolog 3; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL- 1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation.
      
 0.584
Kcna10
Potassium voltage-gated channel subfamily A member 10; Mediates voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The channel activity is up-regulated by cAMP; Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.8/KCNA10 sub-subfamily.
      
 0.564
Etnk2
Ethanolamine kinase 2; Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity.
      
 0.528
Nav1
Neuron navigator 1; May be involved in neuronal migration. Belongs to the Nav/unc-53 family.
      
 0.523
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
Server load: low (28%) [HD]