node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aass | Sccpdh | ENSMUSP00000031707 | ENSMUSP00000040956 | Alpha-aminoadipic semialdehyde synthase, mitochondrial; Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine- oxoglutarate reductase and saccharopine dehydrogenase activity, respectively. | Saccharopine dehydrogenase-like oxidoreductase; Belongs to the saccharopine dehydrogenase family. | 0.499 |
Chst8 | Sccpdh | ENSMUSP00000159050 | ENSMUSP00000040956 | Carbohydrate sulfotransferase 8; Catalyzes the transfer of sulfate to position 4 of non- reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Required for biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Only active against terminal GalNAcbeta1,GalNAcbeta. Not active toward chondroitin. | Saccharopine dehydrogenase-like oxidoreductase; Belongs to the saccharopine dehydrogenase family. | 0.455 |
Chst8 | Tcerg1l | ENSMUSP00000159050 | ENSMUSP00000124476 | Carbohydrate sulfotransferase 8; Catalyzes the transfer of sulfate to position 4 of non- reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Required for biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Only active against terminal GalNAcbeta1,GalNAcbeta. Not active toward chondroitin. | Transcription elongation regulator 1-like protein. | 0.507 |
Fasn | Sccpdh | ENSMUSP00000052872 | ENSMUSP00000040956 | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein. | Saccharopine dehydrogenase-like oxidoreductase; Belongs to the saccharopine dehydrogenase family. | 0.450 |
Foxred1 | Sccpdh | ENSMUSP00000038924 | ENSMUSP00000040956 | FAD-dependent oxidoreductase domain-containing protein 1; Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). Involved in mid-late stages of complex I assembly. | Saccharopine dehydrogenase-like oxidoreductase; Belongs to the saccharopine dehydrogenase family. | 0.496 |
Scamp3 | Sccpdh | ENSMUSP00000112846 | ENSMUSP00000040956 | Secretory carrier-associated membrane protein 3; Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface; Belongs to the SCAMP family. | Saccharopine dehydrogenase-like oxidoreductase; Belongs to the saccharopine dehydrogenase family. | 0.435 |
Sccpdh | Aass | ENSMUSP00000040956 | ENSMUSP00000031707 | Saccharopine dehydrogenase-like oxidoreductase; Belongs to the saccharopine dehydrogenase family. | Alpha-aminoadipic semialdehyde synthase, mitochondrial; Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine- oxoglutarate reductase and saccharopine dehydrogenase activity, respectively. | 0.499 |
Sccpdh | Chst8 | ENSMUSP00000040956 | ENSMUSP00000159050 | Saccharopine dehydrogenase-like oxidoreductase; Belongs to the saccharopine dehydrogenase family. | Carbohydrate sulfotransferase 8; Catalyzes the transfer of sulfate to position 4 of non- reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Required for biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Only active against terminal GalNAcbeta1,GalNAcbeta. Not active toward chondroitin. | 0.455 |
Sccpdh | Fasn | ENSMUSP00000040956 | ENSMUSP00000052872 | Saccharopine dehydrogenase-like oxidoreductase; Belongs to the saccharopine dehydrogenase family. | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein. | 0.450 |
Sccpdh | Foxred1 | ENSMUSP00000040956 | ENSMUSP00000038924 | Saccharopine dehydrogenase-like oxidoreductase; Belongs to the saccharopine dehydrogenase family. | FAD-dependent oxidoreductase domain-containing protein 1; Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). Involved in mid-late stages of complex I assembly. | 0.496 |
Sccpdh | Scamp3 | ENSMUSP00000040956 | ENSMUSP00000112846 | Saccharopine dehydrogenase-like oxidoreductase; Belongs to the saccharopine dehydrogenase family. | Secretory carrier-associated membrane protein 3; Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface; Belongs to the SCAMP family. | 0.435 |
Sccpdh | Stoml1 | ENSMUSP00000040956 | ENSMUSP00000034883 | Saccharopine dehydrogenase-like oxidoreductase; Belongs to the saccharopine dehydrogenase family. | Stomatin-like protein 1; May play a role in cholesterol transfer to late endosomes (By similarity). May play a role in modulating membrane acid-sensing ion channels. Can specifically inhibit proton-gated current of ASIC1 isoform 1. Can increase inactivation speed of ASIC3. May be involved in regulation of proton sensing in dorsal root ganglions ; Belongs to the band 7/mec-2 family. | 0.438 |
Sccpdh | Tcerg1l | ENSMUSP00000040956 | ENSMUSP00000124476 | Saccharopine dehydrogenase-like oxidoreductase; Belongs to the saccharopine dehydrogenase family. | Transcription elongation regulator 1-like protein. | 0.584 |
Sccpdh | Tmem88b | ENSMUSP00000040956 | ENSMUSP00000095349 | Saccharopine dehydrogenase-like oxidoreductase; Belongs to the saccharopine dehydrogenase family. | Transmembrane protein 88B. | 0.465 |
Sccpdh | Tmx3 | ENSMUSP00000040956 | ENSMUSP00000025515 | Saccharopine dehydrogenase-like oxidoreductase; Belongs to the saccharopine dehydrogenase family. | Protein disulfide-isomerase TMX3; Probable disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May act as a dithiol oxidase (By similarity). | 0.531 |
Sccpdh | Tmx4 | ENSMUSP00000040956 | ENSMUSP00000045154 | Saccharopine dehydrogenase-like oxidoreductase; Belongs to the saccharopine dehydrogenase family. | Thioredoxin-related transmembrane protein 4. | 0.518 |
Stoml1 | Sccpdh | ENSMUSP00000034883 | ENSMUSP00000040956 | Stomatin-like protein 1; May play a role in cholesterol transfer to late endosomes (By similarity). May play a role in modulating membrane acid-sensing ion channels. Can specifically inhibit proton-gated current of ASIC1 isoform 1. Can increase inactivation speed of ASIC3. May be involved in regulation of proton sensing in dorsal root ganglions ; Belongs to the band 7/mec-2 family. | Saccharopine dehydrogenase-like oxidoreductase; Belongs to the saccharopine dehydrogenase family. | 0.438 |
Tcerg1l | Chst8 | ENSMUSP00000124476 | ENSMUSP00000159050 | Transcription elongation regulator 1-like protein. | Carbohydrate sulfotransferase 8; Catalyzes the transfer of sulfate to position 4 of non- reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Required for biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Only active against terminal GalNAcbeta1,GalNAcbeta. Not active toward chondroitin. | 0.507 |
Tcerg1l | Sccpdh | ENSMUSP00000124476 | ENSMUSP00000040956 | Transcription elongation regulator 1-like protein. | Saccharopine dehydrogenase-like oxidoreductase; Belongs to the saccharopine dehydrogenase family. | 0.584 |
Tmem88b | Sccpdh | ENSMUSP00000095349 | ENSMUSP00000040956 | Transmembrane protein 88B. | Saccharopine dehydrogenase-like oxidoreductase; Belongs to the saccharopine dehydrogenase family. | 0.465 |