node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Abhd10 | Dip2b | ENSMUSP00000065282 | ENSMUSP00000097777 | Mycophenolic acid acyl-glucuronide esterase, mitochondrial; Abhydrolase domain containing 10 | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.736 |
Abhd10 | Epdr1 | ENSMUSP00000065282 | ENSMUSP00000002885 | Mycophenolic acid acyl-glucuronide esterase, mitochondrial; Abhydrolase domain containing 10 | Ependymin related protein 1 (zebrafish); Belongs to the ependymin family | 0.612 |
Abhd10 | Ina | ENSMUSP00000065282 | ENSMUSP00000041347 | Mycophenolic acid acyl-glucuronide esterase, mitochondrial; Abhydrolase domain containing 10 | Alpha-internexin; Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges (By similarity) | 0.694 |
Abhd10 | Pars2 | ENSMUSP00000065282 | ENSMUSP00000102393 | Mycophenolic acid acyl-glucuronide esterase, mitochondrial; Abhydrolase domain containing 10 | Probable proline--tRNA ligase, mitochondrial; prolyl-tRNA synthetase (mitochondrial)(putative); Belongs to the class-II aminoacyl-tRNA synthetase family | 0.638 |
Dip2b | Abhd10 | ENSMUSP00000097777 | ENSMUSP00000065282 | DIP2 disco-interacting protein 2 homolog B (Drosophila) | Mycophenolic acid acyl-glucuronide esterase, mitochondrial; Abhydrolase domain containing 10 | 0.736 |
Dip2b | Ina | ENSMUSP00000097777 | ENSMUSP00000041347 | DIP2 disco-interacting protein 2 homolog B (Drosophila) | Alpha-internexin; Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges (By similarity) | 0.700 |
Dip2b | Pars2 | ENSMUSP00000097777 | ENSMUSP00000102393 | DIP2 disco-interacting protein 2 homolog B (Drosophila) | Probable proline--tRNA ligase, mitochondrial; prolyl-tRNA synthetase (mitochondrial)(putative); Belongs to the class-II aminoacyl-tRNA synthetase family | 0.633 |
Dync1i1 | Ina | ENSMUSP00000111221 | ENSMUSP00000041347 | Cytoplasmic dynein 1 intermediate chain 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150- glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kin [...] | Alpha-internexin; Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges (By similarity) | 0.715 |
Dync1i1 | Mapt | ENSMUSP00000111221 | ENSMUSP00000097919 | Cytoplasmic dynein 1 intermediate chain 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150- glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kin [...] | Microtubule-associated protein tau; Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabil [...] | 0.730 |
Dync1i1 | Poldip3 | ENSMUSP00000111221 | ENSMUSP00000054548 | Cytoplasmic dynein 1 intermediate chain 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150- glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kin [...] | Polymerase delta-interacting protein 3; Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export; probably mediated by assoociation with the TREX complex (By similarity) | 0.656 |
Epdr1 | Abhd10 | ENSMUSP00000002885 | ENSMUSP00000065282 | Ependymin related protein 1 (zebrafish); Belongs to the ependymin family | Mycophenolic acid acyl-glucuronide esterase, mitochondrial; Abhydrolase domain containing 10 | 0.612 |
Epdr1 | Ina | ENSMUSP00000002885 | ENSMUSP00000041347 | Ependymin related protein 1 (zebrafish); Belongs to the ependymin family | Alpha-internexin; Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges (By similarity) | 0.699 |
Epdr1 | Pars2 | ENSMUSP00000002885 | ENSMUSP00000102393 | Ependymin related protein 1 (zebrafish); Belongs to the ependymin family | Probable proline--tRNA ligase, mitochondrial; prolyl-tRNA synthetase (mitochondrial)(putative); Belongs to the class-II aminoacyl-tRNA synthetase family | 0.598 |
Gan | Ina | ENSMUSP00000124904 | ENSMUSP00000041347 | Kelch-like protein 16 (gigaxonin); Gigaxonin; Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB (By similarity). Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival | Alpha-internexin; Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges (By similarity) | 0.815 |
Grin1 | Ina | ENSMUSP00000028335 | ENSMUSP00000041347 | Glutamate receptor, ionotropic, nmda1 (zeta 1); Glutamate receptor ionotropic, NMDA 1; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition | Alpha-internexin; Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges (By similarity) | 0.786 |
Grin1 | Mapt | ENSMUSP00000028335 | ENSMUSP00000097919 | Glutamate receptor, ionotropic, nmda1 (zeta 1); Glutamate receptor ionotropic, NMDA 1; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition | Microtubule-associated protein tau; Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabil [...] | 0.547 |
Grin1 | Ppp1r9b | ENSMUSP00000028335 | ENSMUSP00000041732 | Glutamate receptor, ionotropic, nmda1 (zeta 1); Glutamate receptor ionotropic, NMDA 1; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition | Protein phosphatase 1, regulatory subunit 9b; Neurabin-2; Seems to act as a scaffold protein in multiple signaling pathways. Modulates excitatory synaptic transmission and dendritic spine morphology. Binds to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May play an important role in linking the actin cytoskeleton to the plasma membrane at the synaptic junction. Believed to target protein phosphatase 1/PP1 to dendritic spines, which are rich in F-actin, and regulates its specificity toward ion channels and other substrates, such as AM [...] | 0.897 |
Ina | Abhd10 | ENSMUSP00000041347 | ENSMUSP00000065282 | Alpha-internexin; Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges (By similarity) | Mycophenolic acid acyl-glucuronide esterase, mitochondrial; Abhydrolase domain containing 10 | 0.694 |
Ina | Dip2b | ENSMUSP00000041347 | ENSMUSP00000097777 | Alpha-internexin; Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges (By similarity) | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.700 |
Ina | Dync1i1 | ENSMUSP00000041347 | ENSMUSP00000111221 | Alpha-internexin; Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges (By similarity) | Cytoplasmic dynein 1 intermediate chain 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150- glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kin [...] | 0.715 |