node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Crnn | Tmprss11b | ENSMUSP00000141980 | ENSMUSP00000042406 | Cornulin. | Transmembrane protease serine 11B-like protein; Serine protease; Belongs to the peptidase S1 family. | 0.515 |
Fam57b | Krt77 | ENSMUSP00000078392 | ENSMUSP00000085311 | Ceramide synthase; Involved in ceramide synthesis. In vitro, isoform 3 stimulates the production of C16-, C18- and C20-ceramides, isoform 1 slightly increases the levels of C18- and C20-ceramides, while isoform 2 exhibits only minimal activity. May interfere with adipogenesis by stimulating ceramide synthesis. | Keratin, type II cytoskeletal 1b. | 0.508 |
Fam57b | Krtap11-1 | ENSMUSP00000078392 | ENSMUSP00000129948 | Ceramide synthase; Involved in ceramide synthesis. In vitro, isoform 3 stimulates the production of C16-, C18- and C20-ceramides, isoform 1 slightly increases the levels of C18- and C20-ceramides, while isoform 2 exhibits only minimal activity. May interfere with adipogenesis by stimulating ceramide synthesis. | Keratin-associated protein 11-1. | 0.575 |
Fam57b | Lce1m | ENSMUSP00000078392 | ENSMUSP00000029520 | Ceramide synthase; Involved in ceramide synthesis. In vitro, isoform 3 stimulates the production of C16-, C18- and C20-ceramides, isoform 1 slightly increases the levels of C18- and C20-ceramides, while isoform 2 exhibits only minimal activity. May interfere with adipogenesis by stimulating ceramide synthesis. | Late cornified envelope 1M. | 0.582 |
Fam57b | Tmprss11b | ENSMUSP00000078392 | ENSMUSP00000042406 | Ceramide synthase; Involved in ceramide synthesis. In vitro, isoform 3 stimulates the production of C16-, C18- and C20-ceramides, isoform 1 slightly increases the levels of C18- and C20-ceramides, while isoform 2 exhibits only minimal activity. May interfere with adipogenesis by stimulating ceramide synthesis. | Transmembrane protease serine 11B-like protein; Serine protease; Belongs to the peptidase S1 family. | 0.511 |
Krt2 | Krt77 | ENSMUSP00000023712 | ENSMUSP00000085311 | Keratin, type II cytoskeletal 2 epidermal; Probably contributes to terminal cornification (By similarity). Associated with keratinocyte activation, proliferation and keratinization (By similarity). Plays a role in the establishment of the epidermal barrier on plantar skin. | Keratin, type II cytoskeletal 1b. | 0.572 |
Krt2 | Tmprss11b | ENSMUSP00000023712 | ENSMUSP00000042406 | Keratin, type II cytoskeletal 2 epidermal; Probably contributes to terminal cornification (By similarity). Associated with keratinocyte activation, proliferation and keratinization (By similarity). Plays a role in the establishment of the epidermal barrier on plantar skin. | Transmembrane protease serine 11B-like protein; Serine protease; Belongs to the peptidase S1 family. | 0.424 |
Krt77 | Fam57b | ENSMUSP00000085311 | ENSMUSP00000078392 | Keratin, type II cytoskeletal 1b. | Ceramide synthase; Involved in ceramide synthesis. In vitro, isoform 3 stimulates the production of C16-, C18- and C20-ceramides, isoform 1 slightly increases the levels of C18- and C20-ceramides, while isoform 2 exhibits only minimal activity. May interfere with adipogenesis by stimulating ceramide synthesis. | 0.508 |
Krt77 | Krt2 | ENSMUSP00000085311 | ENSMUSP00000023712 | Keratin, type II cytoskeletal 1b. | Keratin, type II cytoskeletal 2 epidermal; Probably contributes to terminal cornification (By similarity). Associated with keratinocyte activation, proliferation and keratinization (By similarity). Plays a role in the establishment of the epidermal barrier on plantar skin. | 0.572 |
Krt77 | Lce1m | ENSMUSP00000085311 | ENSMUSP00000029520 | Keratin, type II cytoskeletal 1b. | Late cornified envelope 1M. | 0.529 |
Krt77 | Tmprss11b | ENSMUSP00000085311 | ENSMUSP00000042406 | Keratin, type II cytoskeletal 1b. | Transmembrane protease serine 11B-like protein; Serine protease; Belongs to the peptidase S1 family. | 0.516 |
Krtap11-1 | Fam57b | ENSMUSP00000129948 | ENSMUSP00000078392 | Keratin-associated protein 11-1. | Ceramide synthase; Involved in ceramide synthesis. In vitro, isoform 3 stimulates the production of C16-, C18- and C20-ceramides, isoform 1 slightly increases the levels of C18- and C20-ceramides, while isoform 2 exhibits only minimal activity. May interfere with adipogenesis by stimulating ceramide synthesis. | 0.575 |
Krtap11-1 | Lce1m | ENSMUSP00000129948 | ENSMUSP00000029520 | Keratin-associated protein 11-1. | Late cornified envelope 1M. | 0.489 |
Krtap11-1 | Tmprss11b | ENSMUSP00000129948 | ENSMUSP00000042406 | Keratin-associated protein 11-1. | Transmembrane protease serine 11B-like protein; Serine protease; Belongs to the peptidase S1 family. | 0.408 |
Lce1m | Fam57b | ENSMUSP00000029520 | ENSMUSP00000078392 | Late cornified envelope 1M. | Ceramide synthase; Involved in ceramide synthesis. In vitro, isoform 3 stimulates the production of C16-, C18- and C20-ceramides, isoform 1 slightly increases the levels of C18- and C20-ceramides, while isoform 2 exhibits only minimal activity. May interfere with adipogenesis by stimulating ceramide synthesis. | 0.582 |
Lce1m | Krt77 | ENSMUSP00000029520 | ENSMUSP00000085311 | Late cornified envelope 1M. | Keratin, type II cytoskeletal 1b. | 0.529 |
Lce1m | Krtap11-1 | ENSMUSP00000029520 | ENSMUSP00000129948 | Late cornified envelope 1M. | Keratin-associated protein 11-1. | 0.489 |
Lce1m | Tmprss11b | ENSMUSP00000029520 | ENSMUSP00000042406 | Late cornified envelope 1M. | Transmembrane protease serine 11B-like protein; Serine protease; Belongs to the peptidase S1 family. | 0.463 |
Rdh1 | Skint4 | ENSMUSP00000073322 | ENSMUSP00000102176 | Retinol dehydrogenase 1 (All trans); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Selection and upkeep of intraepithelial T-cells protein 4; May act by engaging a cell surface molecule on immature T- cells in the embryonic thymus. | 0.583 |
Rdh1 | Skint8 | ENSMUSP00000073322 | ENSMUSP00000133268 | Retinol dehydrogenase 1 (All trans); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Selection and upkeep of intraepithelial T-cells protein 8; May act by engaging a cell surface molecule on immature T- cells in the embryonic thymus. | 0.732 |