STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmprss11bTransmembrane protease serine 11B-like protein; Serine protease; Belongs to the peptidase S1 family. (416 aa)    
Predicted Functional Partners:
Krt77
Keratin, type II cytoskeletal 1b.
   
 
 0.516
Skint4
Selection and upkeep of intraepithelial T-cells protein 4; May act by engaging a cell surface molecule on immature T- cells in the embryonic thymus.
   
  
 0.516
Crnn
Cornulin.
   
 
 0.515
Fam57b
Ceramide synthase; Involved in ceramide synthesis. In vitro, isoform 3 stimulates the production of C16-, C18- and C20-ceramides, isoform 1 slightly increases the levels of C18- and C20-ceramides, while isoform 2 exhibits only minimal activity. May interfere with adipogenesis by stimulating ceramide synthesis.
      
 0.511
Tmprss12
Transmembrane protease serine 12.
  
  
0.466
Lce1m
Late cornified envelope 1M.
      
 0.463
Skint8
Selection and upkeep of intraepithelial T-cells protein 8; May act by engaging a cell surface molecule on immature T- cells in the embryonic thymus.
   
    0.461
Rdh1
Retinol dehydrogenase 1 (All trans); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
    0.447
Krt2
Keratin, type II cytoskeletal 2 epidermal; Probably contributes to terminal cornification (By similarity). Associated with keratinocyte activation, proliferation and keratinization (By similarity). Plays a role in the establishment of the epidermal barrier on plantar skin.
   
 
 0.424
Krtap11-1
Keratin-associated protein 11-1.
      
 0.408
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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