node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ano2 | Gng13 | ENSMUSP00000125303 | ENSMUSP00000131648 | Anoctamin-2; Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor- sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina. Belongs to the anoctamin family. | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.439 |
Ano2 | Olfr73 | ENSMUSP00000125303 | ENSMUSP00000149472 | Anoctamin-2; Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor- sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina. Belongs to the anoctamin family. | Olfactory receptor. | 0.489 |
Ano2 | Ric8b | ENSMUSP00000125303 | ENSMUSP00000046981 | Anoctamin-2; Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor- sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina. Belongs to the anoctamin family. | Synembryn-B; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP (By similarity). Able to potentiate G(olf)-alpha-dependent cAMP accumulation suggesting that it may be an important component for odorant signal transduction. | 0.403 |
Ano2 | Rtp1 | ENSMUSP00000125303 | ENSMUSP00000043416 | Anoctamin-2; Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor- sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina. Belongs to the anoctamin family. | Receptor-transporting protein 1; Specifically promotes functional cell surface expression of olfactory receptors, but not of other GPCRs. Belongs to the TMEM7 family. | 0.720 |
Gng13 | Ano2 | ENSMUSP00000131648 | ENSMUSP00000125303 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | Anoctamin-2; Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor- sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina. Belongs to the anoctamin family. | 0.439 |
Gng13 | Olfr1444 | ENSMUSP00000131648 | ENSMUSP00000150212 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | Olfactory receptor 1444; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.674 |
Gng13 | Olfr160 | ENSMUSP00000131648 | ENSMUSP00000148600 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | Olfactory receptor 151; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.718 |
Gng13 | Olfr168 | ENSMUSP00000131648 | ENSMUSP00000149405 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | Olfactory receptor. | 0.674 |
Gng13 | Olfr522 | ENSMUSP00000131648 | ENSMUSP00000057288 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | Olfactory receptor. | 0.674 |
Gng13 | Olfr599 | ENSMUSP00000131648 | ENSMUSP00000149281 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | Olfactory receptor. | 0.676 |
Gng13 | Olfr73 | ENSMUSP00000131648 | ENSMUSP00000149472 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | Olfactory receptor. | 0.788 |
Gng13 | Ric8b | ENSMUSP00000131648 | ENSMUSP00000046981 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | Synembryn-B; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP (By similarity). Able to potentiate G(olf)-alpha-dependent cAMP accumulation suggesting that it may be an important component for odorant signal transduction. | 0.660 |
Gng13 | Rtp1 | ENSMUSP00000131648 | ENSMUSP00000043416 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | Receptor-transporting protein 1; Specifically promotes functional cell surface expression of olfactory receptors, but not of other GPCRs. Belongs to the TMEM7 family. | 0.689 |
Olfr1444 | Gng13 | ENSMUSP00000150212 | ENSMUSP00000131648 | Olfactory receptor 1444; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.674 |
Olfr1444 | Olfr160 | ENSMUSP00000150212 | ENSMUSP00000148600 | Olfactory receptor 1444; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Olfactory receptor 151; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.421 |
Olfr1444 | Olfr168 | ENSMUSP00000150212 | ENSMUSP00000149405 | Olfactory receptor 1444; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Olfactory receptor. | 0.413 |
Olfr1444 | Olfr522 | ENSMUSP00000150212 | ENSMUSP00000057288 | Olfactory receptor 1444; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Olfactory receptor. | 0.425 |
Olfr1444 | Olfr599 | ENSMUSP00000150212 | ENSMUSP00000149281 | Olfactory receptor 1444; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Olfactory receptor. | 0.400 |
Olfr1444 | Olfr73 | ENSMUSP00000150212 | ENSMUSP00000149472 | Olfactory receptor 1444; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Olfactory receptor. | 0.418 |
Olfr1444 | Reep1 | ENSMUSP00000150212 | ENSMUSP00000112662 | Olfactory receptor 1444; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Receptor expression-enhancing protein 1; Required for endoplasmic reticulum (ER) network formation, shaping and remodeling; it links ER tubules to the cytoskeleton. May also enhance the cell surface expression of odorant receptors (By similarity); Belongs to the DP1 family. | 0.400 |