node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AW551984 | Zcchc12 | ENSMUSP00000042582 | ENSMUSP00000110911 | Expressed sequence AW551984. | Zinc finger CCHC domain-containing protein 12; Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic- neuron-specific gene expression. | 0.515 |
Chgb | Zcchc12 | ENSMUSP00000028826 | ENSMUSP00000110911 | Secretogranin-1; Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides. | Zinc finger CCHC domain-containing protein 12; Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic- neuron-specific gene expression. | 0.426 |
Fancm | Pnmal1 | ENSMUSP00000054797 | ENSMUSP00000040929 | Fanconi anemia group M protein homolog; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. Thi [...] | Paraneoplastic antigen-like protein 8A; Belongs to the PNMA family. | 0.680 |
Fancm | Rtl5 | ENSMUSP00000054797 | ENSMUSP00000109261 | Fanconi anemia group M protein homolog; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. Thi [...] | Retrotransposon Gag-like protein 5. | 0.679 |
Fancm | Rtl6 | ENSMUSP00000054797 | ENSMUSP00000069947 | Fanconi anemia group M protein homolog; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. Thi [...] | Retrotransposon Gag-like protein 6. | 0.679 |
Fancm | Rtl9 | ENSMUSP00000054797 | ENSMUSP00000128287 | Fanconi anemia group M protein homolog; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. Thi [...] | Retrotransposon Gag-like protein 9. | 0.679 |
Fancm | Zcchc12 | ENSMUSP00000054797 | ENSMUSP00000110911 | Fanconi anemia group M protein homolog; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. Thi [...] | Zinc finger CCHC domain-containing protein 12; Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic- neuron-specific gene expression. | 0.679 |
Flywch2 | Zcchc12 | ENSMUSP00000024704 | ENSMUSP00000110911 | FLYWCH family member 2. | Zinc finger CCHC domain-containing protein 12; Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic- neuron-specific gene expression. | 0.423 |
Pnmal1 | Fancm | ENSMUSP00000040929 | ENSMUSP00000054797 | Paraneoplastic antigen-like protein 8A; Belongs to the PNMA family. | Fanconi anemia group M protein homolog; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. Thi [...] | 0.680 |
Pnmal1 | Rtl5 | ENSMUSP00000040929 | ENSMUSP00000109261 | Paraneoplastic antigen-like protein 8A; Belongs to the PNMA family. | Retrotransposon Gag-like protein 5. | 0.505 |
Pnmal1 | Rtl6 | ENSMUSP00000040929 | ENSMUSP00000069947 | Paraneoplastic antigen-like protein 8A; Belongs to the PNMA family. | Retrotransposon Gag-like protein 6. | 0.755 |
Pnmal1 | Rtl9 | ENSMUSP00000040929 | ENSMUSP00000128287 | Paraneoplastic antigen-like protein 8A; Belongs to the PNMA family. | Retrotransposon Gag-like protein 9. | 0.647 |
Pnmal1 | Zcchc12 | ENSMUSP00000040929 | ENSMUSP00000110911 | Paraneoplastic antigen-like protein 8A; Belongs to the PNMA family. | Zinc finger CCHC domain-containing protein 12; Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic- neuron-specific gene expression. | 0.713 |
Rtl5 | Fancm | ENSMUSP00000109261 | ENSMUSP00000054797 | Retrotransposon Gag-like protein 5. | Fanconi anemia group M protein homolog; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. Thi [...] | 0.679 |
Rtl5 | Pnmal1 | ENSMUSP00000109261 | ENSMUSP00000040929 | Retrotransposon Gag-like protein 5. | Paraneoplastic antigen-like protein 8A; Belongs to the PNMA family. | 0.505 |
Rtl5 | Rtl9 | ENSMUSP00000109261 | ENSMUSP00000128287 | Retrotransposon Gag-like protein 5. | Retrotransposon Gag-like protein 9. | 0.415 |
Rtl5 | Zcchc12 | ENSMUSP00000109261 | ENSMUSP00000110911 | Retrotransposon Gag-like protein 5. | Zinc finger CCHC domain-containing protein 12; Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic- neuron-specific gene expression. | 0.483 |
Rtl6 | Fancm | ENSMUSP00000069947 | ENSMUSP00000054797 | Retrotransposon Gag-like protein 6. | Fanconi anemia group M protein homolog; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. Thi [...] | 0.679 |
Rtl6 | Pnmal1 | ENSMUSP00000069947 | ENSMUSP00000040929 | Retrotransposon Gag-like protein 6. | Paraneoplastic antigen-like protein 8A; Belongs to the PNMA family. | 0.755 |
Rtl6 | Rtl9 | ENSMUSP00000069947 | ENSMUSP00000128287 | Retrotransposon Gag-like protein 6. | Retrotransposon Gag-like protein 9. | 0.856 |