Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Asb1 | Kctd7 | ENSMUSP00000084054 | ENSMUSP00000044568 | Ankyrin repeat and SOCS box protein 1; May play a role in testis development. Probable substrate- recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Belongs to the ankyrin SOCS box (ASB) family. | BTB/POZ domain-containing protein KCTD7; May be involved in the control of excitability of cortical neurons. | 0.622 |
| Cln5 | Cln6 | ENSMUSP00000022721 | ENSMUSP00000034776 | Ceroid-lipofuscinosis neuronal protein 5 homolog, secreted form; Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane; Belongs to the CLN5 family. | Ceroid-lipofuscinosis, neuronal 6. | 0.955 |
| Cln5 | Cln8 | ENSMUSP00000022721 | ENSMUSP00000027554 | Ceroid-lipofuscinosis neuronal protein 5 homolog, secreted form; Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane; Belongs to the CLN5 family. | Protein CLN8; Could play a role in cell proliferation during neuronal differentiation and in protection against cell death. | 0.916 |
| Cln5 | Kctd7 | ENSMUSP00000022721 | ENSMUSP00000044568 | Ceroid-lipofuscinosis neuronal protein 5 homolog, secreted form; Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane; Belongs to the CLN5 family. | BTB/POZ domain-containing protein KCTD7; May be involved in the control of excitability of cortical neurons. | 0.575 |
| Cln5 | Mfsd8 | ENSMUSP00000022721 | ENSMUSP00000026859 | Ceroid-lipofuscinosis neuronal protein 5 homolog, secreted form; Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane; Belongs to the CLN5 family. | Major facilitator superfamily domain-containing protein 8; May be a carrier that transport small solutes by using chemiosmotic ion gradients; Belongs to the major facilitator superfamily. | 0.881 |
| Cln5 | Ppt1 | ENSMUSP00000022721 | ENSMUSP00000030412 | Ceroid-lipofuscinosis neuronal protein 5 homolog, secreted form; Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane; Belongs to the CLN5 family. | Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons. | 0.913 |
| Cln6 | Cln5 | ENSMUSP00000034776 | ENSMUSP00000022721 | Ceroid-lipofuscinosis, neuronal 6. | Ceroid-lipofuscinosis neuronal protein 5 homolog, secreted form; Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane; Belongs to the CLN5 family. | 0.955 |
| Cln6 | Cln8 | ENSMUSP00000034776 | ENSMUSP00000027554 | Ceroid-lipofuscinosis, neuronal 6. | Protein CLN8; Could play a role in cell proliferation during neuronal differentiation and in protection against cell death. | 0.956 |
| Cln6 | Kctd7 | ENSMUSP00000034776 | ENSMUSP00000044568 | Ceroid-lipofuscinosis, neuronal 6. | BTB/POZ domain-containing protein KCTD7; May be involved in the control of excitability of cortical neurons. | 0.568 |
| Cln6 | Mfsd8 | ENSMUSP00000034776 | ENSMUSP00000026859 | Ceroid-lipofuscinosis, neuronal 6. | Major facilitator superfamily domain-containing protein 8; May be a carrier that transport small solutes by using chemiosmotic ion gradients; Belongs to the major facilitator superfamily. | 0.866 |
| Cln6 | Ppt1 | ENSMUSP00000034776 | ENSMUSP00000030412 | Ceroid-lipofuscinosis, neuronal 6. | Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons. | 0.913 |
| Cln8 | Cln5 | ENSMUSP00000027554 | ENSMUSP00000022721 | Protein CLN8; Could play a role in cell proliferation during neuronal differentiation and in protection against cell death. | Ceroid-lipofuscinosis neuronal protein 5 homolog, secreted form; Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane; Belongs to the CLN5 family. | 0.916 |
| Cln8 | Cln6 | ENSMUSP00000027554 | ENSMUSP00000034776 | Protein CLN8; Could play a role in cell proliferation during neuronal differentiation and in protection against cell death. | Ceroid-lipofuscinosis, neuronal 6. | 0.956 |
| Cln8 | Kctd7 | ENSMUSP00000027554 | ENSMUSP00000044568 | Protein CLN8; Could play a role in cell proliferation during neuronal differentiation and in protection against cell death. | BTB/POZ domain-containing protein KCTD7; May be involved in the control of excitability of cortical neurons. | 0.551 |
| Cln8 | Mfsd8 | ENSMUSP00000027554 | ENSMUSP00000026859 | Protein CLN8; Could play a role in cell proliferation during neuronal differentiation and in protection against cell death. | Major facilitator superfamily domain-containing protein 8; May be a carrier that transport small solutes by using chemiosmotic ion gradients; Belongs to the major facilitator superfamily. | 0.868 |
| Cln8 | Ppt1 | ENSMUSP00000027554 | ENSMUSP00000030412 | Protein CLN8; Could play a role in cell proliferation during neuronal differentiation and in protection against cell death. | Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons. | 0.900 |
| Cul3 | Kctd7 | ENSMUSP00000130738 | ENSMUSP00000044568 | Cullin-3; Core component of multiple cullin-RING-based BCR (BTB-CUL3- RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). BCR complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins (By similarity). As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme (By similarity). The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhi [...] | BTB/POZ domain-containing protein KCTD7; May be involved in the control of excitability of cortical neurons. | 0.657 |
| Cul3 | Klhl11 | ENSMUSP00000130738 | ENSMUSP00000054963 | Cullin-3; Core component of multiple cullin-RING-based BCR (BTB-CUL3- RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). BCR complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins (By similarity). As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme (By similarity). The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhi [...] | Kelch-like protein 11; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. | 0.974 |
| Cul3 | Ube2m | ENSMUSP00000130738 | ENSMUSP00000005714 | Cullin-3; Core component of multiple cullin-RING-based BCR (BTB-CUL3- RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). BCR complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins (By similarity). As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme (By similarity). The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhi [...] | NEDD8-conjugating enzyme Ubc12; Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation (By similarity). | 0.919 |
| Kctd7 | Asb1 | ENSMUSP00000044568 | ENSMUSP00000084054 | BTB/POZ domain-containing protein KCTD7; May be involved in the control of excitability of cortical neurons. | Ankyrin repeat and SOCS box protein 1; May play a role in testis development. Probable substrate- recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Belongs to the ankyrin SOCS box (ASB) family. | 0.622 |
page 1 of 3