node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Clec14a | Zfhx2 | ENSMUSP00000054451 | ENSMUSP00000045156 | C-type lectin domain family 14 member A. | Zinc finger homeobox protein 2; Transcriptional regulator that is critical for the regulation of pain perception and processing of noxious stimuli. | 0.446 |
Elk3 | Zfhx2 | ENSMUSP00000008542 | ENSMUSP00000045156 | ETS domain-containing protein Elk-3; May be a negative regulator of transcription, but can activate transcription when coexpressed with Ras, Src or Mos. Forms a ternary complex with the serum response factor and the ETS and SRF motifs of the Fos serum response element. | Zinc finger homeobox protein 2; Transcriptional regulator that is critical for the regulation of pain perception and processing of noxious stimuli. | 0.418 |
Exosc9 | Gm5148 | ENSMUSP00000029269 | ENSMUSP00000103740 | Exosome complex component RRP45; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cyto [...] | Predicted gene, EG381438. | 0.430 |
Exosc9 | Zfhx2 | ENSMUSP00000029269 | ENSMUSP00000045156 | Exosome complex component RRP45; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cyto [...] | Zinc finger homeobox protein 2; Transcriptional regulator that is critical for the regulation of pain perception and processing of noxious stimuli. | 0.540 |
Gm5148 | Exosc9 | ENSMUSP00000103740 | ENSMUSP00000029269 | Predicted gene, EG381438. | Exosome complex component RRP45; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cyto [...] | 0.430 |
Gm5148 | Zfhx2 | ENSMUSP00000103740 | ENSMUSP00000045156 | Predicted gene, EG381438. | Zinc finger homeobox protein 2; Transcriptional regulator that is critical for the regulation of pain perception and processing of noxious stimuli. | 0.518 |
Inpp5k | Rph3al | ENSMUSP00000006286 | ENSMUSP00000113869 | Inositol polyphosphate 5-phosphatase K; Inositol 5-phosphatase which acts on inositol 1,4,5- trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Has 6- fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5-trisphosphate (By similarity). Negatively regulates assembly of the actin cytoskeleton. Controls insulin-dependent glucose uptake among inositol 3,4,5-trisphosphate phosphatases; therefore, is the specific regulator for insulin signaling in skeletal muscle. | Rab effector Noc2; Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells. Regulates the exocytosis of dense-core vesicles in neuroendocrine cells through interaction with RAB27A. Acts as a potential RAB3B effector protein in epithelial cells. | 0.516 |
Inpp5k | Zfhx2 | ENSMUSP00000006286 | ENSMUSP00000045156 | Inositol polyphosphate 5-phosphatase K; Inositol 5-phosphatase which acts on inositol 1,4,5- trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Has 6- fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5-trisphosphate (By similarity). Negatively regulates assembly of the actin cytoskeleton. Controls insulin-dependent glucose uptake among inositol 3,4,5-trisphosphate phosphatases; therefore, is the specific regulator for insulin signaling in skeletal muscle. | Zinc finger homeobox protein 2; Transcriptional regulator that is critical for the regulation of pain perception and processing of noxious stimuli. | 0.540 |
Pou2f2 | Zfhx2 | ENSMUSP00000104056 | ENSMUSP00000045156 | POU domain, class 2, transcription factor 2; Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform OCT2.5 activates the U2 small nuclear RNA (snRNA) promoter. Isoforms OCT2.1, OCT2.2 and OCT2.3 activate octamer-containing promoters. Isoforms OCT2.4 and OCT2.5 repress some promoters and activate others. Isoform OCT2.7 is unable to bind to the octamer motif, but can still activate the b [...] | Zinc finger homeobox protein 2; Transcriptional regulator that is critical for the regulation of pain perception and processing of noxious stimuli. | 0.429 |
Prdm12 | Zfhx2 | ENSMUSP00000109098 | ENSMUSP00000045156 | PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation. | Zinc finger homeobox protein 2; Transcriptional regulator that is critical for the regulation of pain perception and processing of noxious stimuli. | 0.415 |
Rere | Zfhx2 | ENSMUSP00000101307 | ENSMUSP00000045156 | Arginine-glutamic acid dipeptide repeats protein; Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. | Zinc finger homeobox protein 2; Transcriptional regulator that is critical for the regulation of pain perception and processing of noxious stimuli. | 0.461 |
Rph3al | Inpp5k | ENSMUSP00000113869 | ENSMUSP00000006286 | Rab effector Noc2; Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells. Regulates the exocytosis of dense-core vesicles in neuroendocrine cells through interaction with RAB27A. Acts as a potential RAB3B effector protein in epithelial cells. | Inositol polyphosphate 5-phosphatase K; Inositol 5-phosphatase which acts on inositol 1,4,5- trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Has 6- fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5-trisphosphate (By similarity). Negatively regulates assembly of the actin cytoskeleton. Controls insulin-dependent glucose uptake among inositol 3,4,5-trisphosphate phosphatases; therefore, is the specific regulator for insulin signaling in skeletal muscle. | 0.516 |
Rph3al | Zfhx2 | ENSMUSP00000113869 | ENSMUSP00000045156 | Rab effector Noc2; Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells. Regulates the exocytosis of dense-core vesicles in neuroendocrine cells through interaction with RAB27A. Acts as a potential RAB3B effector protein in epithelial cells. | Zinc finger homeobox protein 2; Transcriptional regulator that is critical for the regulation of pain perception and processing of noxious stimuli. | 0.477 |
Tecpr2 | Zfhx2 | ENSMUSP00000126749 | ENSMUSP00000045156 | Tectonin beta-propeller repeat-containing 2. | Zinc finger homeobox protein 2; Transcriptional regulator that is critical for the regulation of pain perception and processing of noxious stimuli. | 0.468 |
Zfhx2 | Clec14a | ENSMUSP00000045156 | ENSMUSP00000054451 | Zinc finger homeobox protein 2; Transcriptional regulator that is critical for the regulation of pain perception and processing of noxious stimuli. | C-type lectin domain family 14 member A. | 0.446 |
Zfhx2 | Elk3 | ENSMUSP00000045156 | ENSMUSP00000008542 | Zinc finger homeobox protein 2; Transcriptional regulator that is critical for the regulation of pain perception and processing of noxious stimuli. | ETS domain-containing protein Elk-3; May be a negative regulator of transcription, but can activate transcription when coexpressed with Ras, Src or Mos. Forms a ternary complex with the serum response factor and the ETS and SRF motifs of the Fos serum response element. | 0.418 |
Zfhx2 | Exosc9 | ENSMUSP00000045156 | ENSMUSP00000029269 | Zinc finger homeobox protein 2; Transcriptional regulator that is critical for the regulation of pain perception and processing of noxious stimuli. | Exosome complex component RRP45; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cyto [...] | 0.540 |
Zfhx2 | Gm5148 | ENSMUSP00000045156 | ENSMUSP00000103740 | Zinc finger homeobox protein 2; Transcriptional regulator that is critical for the regulation of pain perception and processing of noxious stimuli. | Predicted gene, EG381438. | 0.518 |
Zfhx2 | Inpp5k | ENSMUSP00000045156 | ENSMUSP00000006286 | Zinc finger homeobox protein 2; Transcriptional regulator that is critical for the regulation of pain perception and processing of noxious stimuli. | Inositol polyphosphate 5-phosphatase K; Inositol 5-phosphatase which acts on inositol 1,4,5- trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Has 6- fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5-trisphosphate (By similarity). Negatively regulates assembly of the actin cytoskeleton. Controls insulin-dependent glucose uptake among inositol 3,4,5-trisphosphate phosphatases; therefore, is the specific regulator for insulin signaling in skeletal muscle. | 0.540 |
Zfhx2 | Pou2f2 | ENSMUSP00000045156 | ENSMUSP00000104056 | Zinc finger homeobox protein 2; Transcriptional regulator that is critical for the regulation of pain perception and processing of noxious stimuli. | POU domain, class 2, transcription factor 2; Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform OCT2.5 activates the U2 small nuclear RNA (snRNA) promoter. Isoforms OCT2.1, OCT2.2 and OCT2.3 activate octamer-containing promoters. Isoforms OCT2.4 and OCT2.5 repress some promoters and activate others. Isoform OCT2.7 is unable to bind to the octamer motif, but can still activate the b [...] | 0.429 |