node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Erc1 | Erc2 | ENSMUSP00000139031 | ENSMUSP00000087773 | ELKS/Rab6-interacting/CAST family member 1; Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex (By similarity). May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport. | ERC protein 2; Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ. | 0.466 |
Erc1 | Rimbp2 | ENSMUSP00000139031 | ENSMUSP00000142455 | ELKS/Rab6-interacting/CAST family member 1; Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex (By similarity). May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport. | RIMS-binding protein 2; Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B. | 0.630 |
Erc1 | Rims4 | ENSMUSP00000139031 | ENSMUSP00000045637 | ELKS/Rab6-interacting/CAST family member 1; Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex (By similarity). May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport. | Regulating synaptic membrane exocytosis protein 4; Regulates synaptic membrane exocytosis. | 0.512 |
Erc2 | Erc1 | ENSMUSP00000087773 | ENSMUSP00000139031 | ERC protein 2; Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ. | ELKS/Rab6-interacting/CAST family member 1; Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex (By similarity). May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport. | 0.466 |
Erc2 | Rimbp2 | ENSMUSP00000087773 | ENSMUSP00000142455 | ERC protein 2; Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ. | RIMS-binding protein 2; Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B. | 0.592 |
Erc2 | Rims4 | ENSMUSP00000087773 | ENSMUSP00000045637 | ERC protein 2; Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ. | Regulating synaptic membrane exocytosis protein 4; Regulates synaptic membrane exocytosis. | 0.489 |
Erc2 | Srcin1 | ENSMUSP00000087773 | ENSMUSP00000103222 | ERC protein 2; Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ. | SRC kinase signaling inhibitor 1; Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance (By similarity). | 0.439 |
Pcyox1 | Pyurf | ENSMUSP00000032065 | ENSMUSP00000050958 | Prenylcysteine oxidase; Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine (By similarity); Belongs to the prenylcysteine oxidase family. | Protein preY, mitochondrial. | 0.501 |
Pcyox1 | Rims4 | ENSMUSP00000032065 | ENSMUSP00000045637 | Prenylcysteine oxidase; Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine (By similarity); Belongs to the prenylcysteine oxidase family. | Regulating synaptic membrane exocytosis protein 4; Regulates synaptic membrane exocytosis. | 0.569 |
Pyurf | Pcyox1 | ENSMUSP00000050958 | ENSMUSP00000032065 | Protein preY, mitochondrial. | Prenylcysteine oxidase; Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine (By similarity); Belongs to the prenylcysteine oxidase family. | 0.501 |
Pyurf | Rims4 | ENSMUSP00000050958 | ENSMUSP00000045637 | Protein preY, mitochondrial. | Regulating synaptic membrane exocytosis protein 4; Regulates synaptic membrane exocytosis. | 0.609 |
Rab3c | Rimbp2 | ENSMUSP00000132945 | ENSMUSP00000142455 | Ras-related protein Rab-3C; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | RIMS-binding protein 2; Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B. | 0.478 |
Rab3c | Rims4 | ENSMUSP00000132945 | ENSMUSP00000045637 | Ras-related protein Rab-3C; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | Regulating synaptic membrane exocytosis protein 4; Regulates synaptic membrane exocytosis. | 0.481 |
Rab3c | Rph3a | ENSMUSP00000132945 | ENSMUSP00000078198 | Ras-related protein Rab-3C; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | Rabphilin-3A; Plays an essential role in docking and fusion steps of regulated exocytosis (By similarity). At the presynaptic level, RPH3A is recruited by RAB3A to the synaptic vesicle membrane in a GTP- dependent manner where it modulates synaptic vesicle trafficking and calcium-triggered neurotransmitter release (By similarity). In the post-synaptic compartment, forms a ternary complex with GRIN2A and DLG4 and regulates NMDA receptor stability. Plays also a role in the exocytosis of arginine vasopressin hormone (By similarity). | 0.759 |
Rimbp2 | Erc1 | ENSMUSP00000142455 | ENSMUSP00000139031 | RIMS-binding protein 2; Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B. | ELKS/Rab6-interacting/CAST family member 1; Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex (By similarity). May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport. | 0.630 |
Rimbp2 | Erc2 | ENSMUSP00000142455 | ENSMUSP00000087773 | RIMS-binding protein 2; Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B. | ERC protein 2; Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ. | 0.592 |
Rimbp2 | Rab3c | ENSMUSP00000142455 | ENSMUSP00000132945 | RIMS-binding protein 2; Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B. | Ras-related protein Rab-3C; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | 0.478 |
Rimbp2 | Rims4 | ENSMUSP00000142455 | ENSMUSP00000045637 | RIMS-binding protein 2; Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B. | Regulating synaptic membrane exocytosis protein 4; Regulates synaptic membrane exocytosis. | 0.519 |
Rims4 | Erc1 | ENSMUSP00000045637 | ENSMUSP00000139031 | Regulating synaptic membrane exocytosis protein 4; Regulates synaptic membrane exocytosis. | ELKS/Rab6-interacting/CAST family member 1; Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex (By similarity). May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport. | 0.512 |
Rims4 | Erc2 | ENSMUSP00000045637 | ENSMUSP00000087773 | Regulating synaptic membrane exocytosis protein 4; Regulates synaptic membrane exocytosis. | ERC protein 2; Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ. | 0.489 |