node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
2610301B20Rik | 4930402H24Rik | ENSMUSP00000079361 | ENSMUSP00000046992 | Protein C8orf37 homolog; May be involved in photoreceptor outer segment disk morphogenesis. | Uncharacterized protein C20orf194 homolog; May act as an effector for ARL3. | 0.538 |
2610301B20Rik | Chpf | ENSMUSP00000079361 | ENSMUSP00000078199 | Protein C8orf37 homolog; May be involved in photoreceptor outer segment disk morphogenesis. | Chondroitin sulfate synthase 2; Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of the elongating chondroitin polymer (By similarity). Isoform 2 may facilitate PRKN transport into the mitochondria. In collaboration with PRKN, isoform 2 may enhance cell viability and protect cells from oxidative stress (By similarity). | 0.449 |
2610301B20Rik | Cmtm6 | ENSMUSP00000079361 | ENSMUSP00000035007 | Protein C8orf37 homolog; May be involved in photoreceptor outer segment disk morphogenesis. | CKLF-like MARVEL transmembrane domain-containing protein 6; Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately trigge [...] | 0.448 |
2610301B20Rik | Olfr1371 | ENSMUSP00000079361 | ENSMUSP00000075241 | Protein C8orf37 homolog; May be involved in photoreceptor outer segment disk morphogenesis. | Olfactory receptor. | 0.525 |
4930402H24Rik | 2610301B20Rik | ENSMUSP00000046992 | ENSMUSP00000079361 | Uncharacterized protein C20orf194 homolog; May act as an effector for ARL3. | Protein C8orf37 homolog; May be involved in photoreceptor outer segment disk morphogenesis. | 0.538 |
4930402H24Rik | Chpf | ENSMUSP00000046992 | ENSMUSP00000078199 | Uncharacterized protein C20orf194 homolog; May act as an effector for ARL3. | Chondroitin sulfate synthase 2; Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of the elongating chondroitin polymer (By similarity). Isoform 2 may facilitate PRKN transport into the mitochondria. In collaboration with PRKN, isoform 2 may enhance cell viability and protect cells from oxidative stress (By similarity). | 0.538 |
4930402H24Rik | Cmtm6 | ENSMUSP00000046992 | ENSMUSP00000035007 | Uncharacterized protein C20orf194 homolog; May act as an effector for ARL3. | CKLF-like MARVEL transmembrane domain-containing protein 6; Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately trigge [...] | 0.538 |
4930402H24Rik | Dynlrb1 | ENSMUSP00000046992 | ENSMUSP00000114928 | Uncharacterized protein C20orf194 homolog; May act as an effector for ARL3. | Dynein light chain roadblock-type 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. | 0.404 |
4930402H24Rik | Fam168a | ENSMUSP00000046992 | ENSMUSP00000038233 | Uncharacterized protein C20orf194 homolog; May act as an effector for ARL3. | Protein FAM168A; In cancer context, protects cells from induced-DNA damage and apoptosis. Acts, at least in part, through PI3K/AKT/NFKB signaling pathway and by preventing POLB degradation. Decreases POLB ubiquitation and stabilizes its protein levels. | 0.448 |
4930402H24Rik | Olfr1371 | ENSMUSP00000046992 | ENSMUSP00000075241 | Uncharacterized protein C20orf194 homolog; May act as an effector for ARL3. | Olfactory receptor. | 0.538 |
Chpf | 2610301B20Rik | ENSMUSP00000078199 | ENSMUSP00000079361 | Chondroitin sulfate synthase 2; Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of the elongating chondroitin polymer (By similarity). Isoform 2 may facilitate PRKN transport into the mitochondria. In collaboration with PRKN, isoform 2 may enhance cell viability and protect cells from oxidative stress (By similarity). | Protein C8orf37 homolog; May be involved in photoreceptor outer segment disk morphogenesis. | 0.449 |
Chpf | 4930402H24Rik | ENSMUSP00000078199 | ENSMUSP00000046992 | Chondroitin sulfate synthase 2; Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of the elongating chondroitin polymer (By similarity). Isoform 2 may facilitate PRKN transport into the mitochondria. In collaboration with PRKN, isoform 2 may enhance cell viability and protect cells from oxidative stress (By similarity). | Uncharacterized protein C20orf194 homolog; May act as an effector for ARL3. | 0.538 |
Cmtm6 | 2610301B20Rik | ENSMUSP00000035007 | ENSMUSP00000079361 | CKLF-like MARVEL transmembrane domain-containing protein 6; Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately trigge [...] | Protein C8orf37 homolog; May be involved in photoreceptor outer segment disk morphogenesis. | 0.448 |
Cmtm6 | 4930402H24Rik | ENSMUSP00000035007 | ENSMUSP00000046992 | CKLF-like MARVEL transmembrane domain-containing protein 6; Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately trigge [...] | Uncharacterized protein C20orf194 homolog; May act as an effector for ARL3. | 0.538 |
Dynlrb1 | 4930402H24Rik | ENSMUSP00000114928 | ENSMUSP00000046992 | Dynein light chain roadblock-type 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. | Uncharacterized protein C20orf194 homolog; May act as an effector for ARL3. | 0.404 |
Fam168a | 4930402H24Rik | ENSMUSP00000038233 | ENSMUSP00000046992 | Protein FAM168A; In cancer context, protects cells from induced-DNA damage and apoptosis. Acts, at least in part, through PI3K/AKT/NFKB signaling pathway and by preventing POLB degradation. Decreases POLB ubiquitation and stabilizes its protein levels. | Uncharacterized protein C20orf194 homolog; May act as an effector for ARL3. | 0.448 |
Olfr1371 | 2610301B20Rik | ENSMUSP00000075241 | ENSMUSP00000079361 | Olfactory receptor. | Protein C8orf37 homolog; May be involved in photoreceptor outer segment disk morphogenesis. | 0.525 |
Olfr1371 | 4930402H24Rik | ENSMUSP00000075241 | ENSMUSP00000046992 | Olfactory receptor. | Uncharacterized protein C20orf194 homolog; May act as an effector for ARL3. | 0.538 |