node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ddx18 | Ebna1bp2 | ENSMUSP00000001724 | ENSMUSP00000030501 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | 0.982 |
Ddx18 | Ftsj3 | ENSMUSP00000001724 | ENSMUSP00000021048 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3; RNA 2'-O-methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. | 0.990 |
Ddx18 | Gtpbp4 | ENSMUSP00000001724 | ENSMUSP00000152412 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | 0.997 |
Ddx18 | Mrto4 | ENSMUSP00000001724 | ENSMUSP00000099561 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | mRNA turnover protein 4 homolog; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. | 0.993 |
Ddx18 | Nifk | ENSMUSP00000001724 | ENSMUSP00000027626 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | MKI67 FHA domain-interacting nucleolar phosphoprotein. | 0.999 |
Ddx18 | Nip7 | ENSMUSP00000001724 | ENSMUSP00000034392 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | 60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly. | 0.988 |
Ddx18 | Noc2l | ENSMUSP00000001724 | ENSMUSP00000137253 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | Nucleolar complex protein 2 homolog; Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis (By similarity). | 0.995 |
Ddx18 | Nop2 | ENSMUSP00000001724 | ENSMUSP00000047123 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | Probable 28S rRNA (cytosine-C(5))-methyltransferase; Involved in ribosomal large subunit assembly. S-adenosyl-L- methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 4447 in 28S rRNA. May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. | 0.970 |
Ddx18 | Rpf2 | ENSMUSP00000001724 | ENSMUSP00000138581 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus; Belongs to the RPF2 family. | 0.989 |
Ddx18 | Rsl1d1 | ENSMUSP00000001724 | ENSMUSP00000113431 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | Ribosomal L1 domain-containing protein 1; Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage. | 0.998 |
Ebna1bp2 | Ddx18 | ENSMUSP00000030501 | ENSMUSP00000001724 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | 0.982 |
Ebna1bp2 | Ftsj3 | ENSMUSP00000030501 | ENSMUSP00000021048 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3; RNA 2'-O-methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. | 0.996 |
Ebna1bp2 | Gtpbp4 | ENSMUSP00000030501 | ENSMUSP00000152412 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | 0.993 |
Ebna1bp2 | Mrto4 | ENSMUSP00000030501 | ENSMUSP00000099561 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | mRNA turnover protein 4 homolog; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. | 0.994 |
Ebna1bp2 | Nifk | ENSMUSP00000030501 | ENSMUSP00000027626 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | MKI67 FHA domain-interacting nucleolar phosphoprotein. | 0.998 |
Ebna1bp2 | Nip7 | ENSMUSP00000030501 | ENSMUSP00000034392 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | 60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly. | 0.996 |
Ebna1bp2 | Noc2l | ENSMUSP00000030501 | ENSMUSP00000137253 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Nucleolar complex protein 2 homolog; Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis (By similarity). | 0.997 |
Ebna1bp2 | Nop2 | ENSMUSP00000030501 | ENSMUSP00000047123 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Probable 28S rRNA (cytosine-C(5))-methyltransferase; Involved in ribosomal large subunit assembly. S-adenosyl-L- methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 4447 in 28S rRNA. May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. | 0.978 |
Ebna1bp2 | Rpf2 | ENSMUSP00000030501 | ENSMUSP00000138581 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus; Belongs to the RPF2 family. | 0.996 |
Ebna1bp2 | Rsl1d1 | ENSMUSP00000030501 | ENSMUSP00000113431 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Ribosomal L1 domain-containing protein 1; Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage. | 0.995 |