node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Armcx2 | Ccdc70 | ENSMUSP00000127305 | ENSMUSP00000017193 | Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells. | Coiled-coil domain-containing protein 70. | 0.574 |
Armcx2 | Fam192a | ENSMUSP00000127305 | ENSMUSP00000034226 | Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells. | PSME3-interacting protein; Promotes the association of the proteasome activator complex subunit PSME3 with the 20S proteasome and regulates its activity. Inhibits PSME3-mediated degradation of some proteasome substrates, probably by affecting their diffusion rate into the catalytic chamber of the proteasome. Also inhibits the interaction of PSME3 with COIL, inhibits accumulation of PSME3 in Cajal bodies and positively regulates the number of Cajal bodies in the nucleus. | 0.564 |
Armcx2 | Gsto1 | ENSMUSP00000127305 | ENSMUSP00000026050 | Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells. | Glutathione S-transferase omega-1; Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. Belongs to the GST superfamily. Omega family. | 0.583 |
Armcx2 | Gzmb | ENSMUSP00000127305 | ENSMUSP00000015581 | Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells. | Granzyme B(G,H); This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis (By similarity). | 0.558 |
Armcx2 | Habp4 | ENSMUSP00000127305 | ENSMUSP00000021929 | Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells. | Intracellular hyaluronan-binding protein 4; RNA-binding protein that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation. Negatively regulates DNA-binding activity of the transcription factor MEF2C in myocardial cells in response to mechanical stress. Plays a role in pre- mRNA splicing regulation. Binds (via C-terminus) to poly(U) RNA. Involved in mRNA translation regulation, probably at the initiation step. Seems to play a role in PML-nuclear bodies formation (By similarity). | 0.556 |
Armcx2 | Rxrg | ENSMUSP00000127305 | ENSMUSP00000015987 | Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells. | Retinoic acid receptor RXR-gamma; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity). | 0.577 |
Armcx2 | Sult5a1 | ENSMUSP00000127305 | ENSMUSP00000000755 | Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells. | Sulfotransferase; Belongs to the sulfotransferase 1 family. | 0.639 |
Armcx2 | Txnrd2 | ENSMUSP00000127305 | ENSMUSP00000146030 | Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells. | Thioredoxin reductase 2, mitochondrial; Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox-regulated cell signaling. | 0.565 |
Armcx2 | Wdr49 | ENSMUSP00000127305 | ENSMUSP00000144721 | Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells. | WD repeat domain 49. | 0.595 |
Armcx2 | Xrra1 | ENSMUSP00000127305 | ENSMUSP00000035929 | Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells. | X-ray radiation resistance-associated protein 1; May be involved in the response of cells to X-ray radiation. | 0.611 |
Ccdc70 | Armcx2 | ENSMUSP00000017193 | ENSMUSP00000127305 | Coiled-coil domain-containing protein 70. | Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells. | 0.574 |
Fam192a | Armcx2 | ENSMUSP00000034226 | ENSMUSP00000127305 | PSME3-interacting protein; Promotes the association of the proteasome activator complex subunit PSME3 with the 20S proteasome and regulates its activity. Inhibits PSME3-mediated degradation of some proteasome substrates, probably by affecting their diffusion rate into the catalytic chamber of the proteasome. Also inhibits the interaction of PSME3 with COIL, inhibits accumulation of PSME3 in Cajal bodies and positively regulates the number of Cajal bodies in the nucleus. | Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells. | 0.564 |
Gsto1 | Armcx2 | ENSMUSP00000026050 | ENSMUSP00000127305 | Glutathione S-transferase omega-1; Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. Belongs to the GST superfamily. Omega family. | Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells. | 0.583 |
Gsto1 | Gzmb | ENSMUSP00000026050 | ENSMUSP00000015581 | Glutathione S-transferase omega-1; Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. Belongs to the GST superfamily. Omega family. | Granzyme B(G,H); This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis (By similarity). | 0.462 |
Gsto1 | Rxrg | ENSMUSP00000026050 | ENSMUSP00000015987 | Glutathione S-transferase omega-1; Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. Belongs to the GST superfamily. Omega family. | Retinoic acid receptor RXR-gamma; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity). | 0.607 |
Gsto1 | Sult5a1 | ENSMUSP00000026050 | ENSMUSP00000000755 | Glutathione S-transferase omega-1; Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. Belongs to the GST superfamily. Omega family. | Sulfotransferase; Belongs to the sulfotransferase 1 family. | 0.639 |
Gzmb | Armcx2 | ENSMUSP00000015581 | ENSMUSP00000127305 | Granzyme B(G,H); This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis (By similarity). | Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells. | 0.558 |
Gzmb | Gsto1 | ENSMUSP00000015581 | ENSMUSP00000026050 | Granzyme B(G,H); This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis (By similarity). | Glutathione S-transferase omega-1; Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. Belongs to the GST superfamily. Omega family. | 0.462 |
Gzmb | Rxrg | ENSMUSP00000015581 | ENSMUSP00000015987 | Granzyme B(G,H); This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis (By similarity). | Retinoic acid receptor RXR-gamma; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity). | 0.530 |
Gzmb | Sult5a1 | ENSMUSP00000015581 | ENSMUSP00000000755 | Granzyme B(G,H); This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis (By similarity). | Sulfotransferase; Belongs to the sulfotransferase 1 family. | 0.532 |