node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Apoa5 | Mat1a | ENSMUSP00000113413 | ENSMUSP00000153488 | Apolipoprotein A-V; Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and an inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages (By similarity). Binds heparin (By similarity). | S-adenosylmethionine synthase isoform type-1; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate; Belongs to the AdoMet synthase family. | 0.581 |
Apoa5 | Slc25a47 | ENSMUSP00000113413 | ENSMUSP00000050329 | Apolipoprotein A-V; Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and an inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages (By similarity). Binds heparin (By similarity). | Solute carrier family 25 member 47; Uncoupling protein which may catalyze the physiological 'proton leak' in liver; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.489 |
Cfap20 | Slc25a47 | ENSMUSP00000034249 | ENSMUSP00000050329 | Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation (By similarity). | Solute carrier family 25 member 47; Uncoupling protein which may catalyze the physiological 'proton leak' in liver; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.455 |
Fau | Rpl14 | ENSMUSP00000136358 | ENSMUSP00000131489 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | 60S ribosomal protein L14; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL14 family. | 0.999 |
Fau | Rpl37a | ENSMUSP00000136358 | ENSMUSP00000058919 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | 60S ribosomal protein L37a; Belongs to the eukaryotic ribosomal protein eL43 family. | 0.999 |
Fau | Rpl6 | ENSMUSP00000136358 | ENSMUSP00000031617 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | 60S ribosomal protein L6; Component of the large ribosomal subunit. | 0.999 |
Fau | Rpl8 | ENSMUSP00000136358 | ENSMUSP00000155657 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | 60S ribosomal protein L8; Component of the large ribosomal subunit. Belongs to the universal ribosomal protein uL2 family. | 0.999 |
Fau | Rps11 | ENSMUSP00000136358 | ENSMUSP00000003521 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | 40S ribosomal protein S11. | 0.999 |
Fau | Rps23 | ENSMUSP00000136358 | ENSMUSP00000054490 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | 40S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] | 0.999 |
Fau | Slc25a47 | ENSMUSP00000136358 | ENSMUSP00000050329 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | Solute carrier family 25 member 47; Uncoupling protein which may catalyze the physiological 'proton leak' in liver; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.772 |
Mat1a | Apoa5 | ENSMUSP00000153488 | ENSMUSP00000113413 | S-adenosylmethionine synthase isoform type-1; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate; Belongs to the AdoMet synthase family. | Apolipoprotein A-V; Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and an inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages (By similarity). Binds heparin (By similarity). | 0.581 |
Mat1a | Slc25a47 | ENSMUSP00000153488 | ENSMUSP00000050329 | S-adenosylmethionine synthase isoform type-1; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate; Belongs to the AdoMet synthase family. | Solute carrier family 25 member 47; Uncoupling protein which may catalyze the physiological 'proton leak' in liver; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.461 |
Rpl14 | Fau | ENSMUSP00000131489 | ENSMUSP00000136358 | 60S ribosomal protein L14; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL14 family. | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | 0.999 |
Rpl14 | Rpl37a | ENSMUSP00000131489 | ENSMUSP00000058919 | 60S ribosomal protein L14; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL14 family. | 60S ribosomal protein L37a; Belongs to the eukaryotic ribosomal protein eL43 family. | 0.999 |
Rpl14 | Rpl6 | ENSMUSP00000131489 | ENSMUSP00000031617 | 60S ribosomal protein L14; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL14 family. | 60S ribosomal protein L6; Component of the large ribosomal subunit. | 0.999 |
Rpl14 | Rpl8 | ENSMUSP00000131489 | ENSMUSP00000155657 | 60S ribosomal protein L14; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL14 family. | 60S ribosomal protein L8; Component of the large ribosomal subunit. Belongs to the universal ribosomal protein uL2 family. | 0.999 |
Rpl14 | Rps11 | ENSMUSP00000131489 | ENSMUSP00000003521 | 60S ribosomal protein L14; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL14 family. | 40S ribosomal protein S11. | 0.999 |
Rpl14 | Rps23 | ENSMUSP00000131489 | ENSMUSP00000054490 | 60S ribosomal protein L14; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL14 family. | 40S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] | 0.999 |
Rpl14 | Slc25a47 | ENSMUSP00000131489 | ENSMUSP00000050329 | 60S ribosomal protein L14; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL14 family. | Solute carrier family 25 member 47; Uncoupling protein which may catalyze the physiological 'proton leak' in liver; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.549 |
Rpl37a | Fau | ENSMUSP00000058919 | ENSMUSP00000136358 | 60S ribosomal protein L37a; Belongs to the eukaryotic ribosomal protein eL43 family. | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | 0.999 |