STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmem123Porimin; Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability; Belongs to the CD164 family. (195 aa)    
Predicted Functional Partners:
Cfap300
Cilia- and flagella-associated protein 300; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. May play a role in outer and inner dynein arm assembly; Belongs to the CFAP300 family.
    
 
 0.569
Sod2
Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family.
   
 
 0.540
Acsf2
Medium-chain acyl-CoA ligase ACSF2, mitochondrial; Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipocyte differentiation; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.539
Mrpl13
39S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family.
   
 
 0.529
Mrpl3
39S ribosomal protein L3, mitochondrial; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.525
Mrpl21
39S ribosomal protein L21, mitochondrial.
  
   0.507
Mrpl11
39S ribosomal protein L11, mitochondrial; Belongs to the universal ribosomal protein uL11 family.
   
 
 0.507
Adgrd1
Adhesion G-protein coupled receptor D1; Orphan receptor. Signals via G(s)-alpha family of G-proteins. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
   
 
 0.507
Mrpl24
39S ribosomal protein L24, mitochondrial; Belongs to the universal ribosomal protein uL24 family.
   
   0.504
Rpl23
60S ribosomal protein L23.
   
 
 0.499
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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