node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
2310002L09Rik | Abra | ENSMUSP00000092633 | ENSMUSP00000051973 | RIKEN cDNA 2310002L09 gene. | Actin-binding Rho-activating protein; Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling. | 0.554 |
2310002L09Rik | Ckmt2 | ENSMUSP00000092633 | ENSMUSP00000022122 | RIKEN cDNA 2310002L09 gene. | Creatine kinase S-type, mitochondrial; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa (By similarity). | 0.572 |
2310002L09Rik | Itgb1bp2 | ENSMUSP00000092633 | ENSMUSP00000033674 | RIKEN cDNA 2310002L09 gene. | Integrin beta-1-binding protein 2; May play a role during maturation and/or organization of muscles cells. | 0.468 |
2310002L09Rik | Lmod3 | ENSMUSP00000092633 | ENSMUSP00000093315 | RIKEN cDNA 2310002L09 gene. | Leiomodin-3; Essential for the organization of sarcomeric actin thin filaments in skeletal muscle. Increases the rate of actin polymerization (By similarity). Belongs to the tropomodulin family. | 0.431 |
2310002L09Rik | Trdn | ENSMUSP00000092633 | ENSMUSP00000093436 | RIKEN cDNA 2310002L09 gene. | Triadin; Contributes to the regulation of lumenal Ca2+ release via the sarcoplasmic reticulum calcium release channels RYR1 and RYR2, a key step in triggering skeletal and heart muscle contraction. Required for normal organization of the triad junction, where T-tubules and the sarcoplasmic reticulum terminal cisternae are in close contact. Required for normal skeletal muscle strength. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats. | 0.401 |
Ablim2 | Abra | ENSMUSP00000123525 | ENSMUSP00000051973 | Actin-binding LIM protein 2; May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity. | Actin-binding Rho-activating protein; Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling. | 0.744 |
Ablim3 | Abra | ENSMUSP00000041243 | ENSMUSP00000051973 | Actin-binding LIM protein 3; May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity. | Actin-binding Rho-activating protein; Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling. | 0.740 |
Abra | 2310002L09Rik | ENSMUSP00000051973 | ENSMUSP00000092633 | Actin-binding Rho-activating protein; Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling. | RIKEN cDNA 2310002L09 gene. | 0.554 |
Abra | Ablim2 | ENSMUSP00000051973 | ENSMUSP00000123525 | Actin-binding Rho-activating protein; Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling. | Actin-binding LIM protein 2; May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity. | 0.744 |
Abra | Ablim3 | ENSMUSP00000051973 | ENSMUSP00000041243 | Actin-binding Rho-activating protein; Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling. | Actin-binding LIM protein 3; May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity. | 0.740 |
Abra | Ckmt2 | ENSMUSP00000051973 | ENSMUSP00000022122 | Actin-binding Rho-activating protein; Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling. | Creatine kinase S-type, mitochondrial; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa (By similarity). | 0.571 |
Abra | Itgb1bp2 | ENSMUSP00000051973 | ENSMUSP00000033674 | Actin-binding Rho-activating protein; Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling. | Integrin beta-1-binding protein 2; May play a role during maturation and/or organization of muscles cells. | 0.576 |
Abra | Lmod3 | ENSMUSP00000051973 | ENSMUSP00000093315 | Actin-binding Rho-activating protein; Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling. | Leiomodin-3; Essential for the organization of sarcomeric actin thin filaments in skeletal muscle. Increases the rate of actin polymerization (By similarity). Belongs to the tropomodulin family. | 0.536 |
Abra | Myoz2 | ENSMUSP00000051973 | ENSMUSP00000029761 | Actin-binding Rho-activating protein; Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling. | Myozenin-2; Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis. | 0.741 |
Abra | Slc4a1 | ENSMUSP00000051973 | ENSMUSP00000006749 | Actin-binding Rho-activating protein; Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling. | Band 3 anion transport protein; Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Major integral membrane glycoprotein of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride- bicarbonate exch [...] | 0.490 |
Abra | Trdn | ENSMUSP00000051973 | ENSMUSP00000093436 | Actin-binding Rho-activating protein; Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling. | Triadin; Contributes to the regulation of lumenal Ca2+ release via the sarcoplasmic reticulum calcium release channels RYR1 and RYR2, a key step in triggering skeletal and heart muscle contraction. Required for normal organization of the triad junction, where T-tubules and the sarcoplasmic reticulum terminal cisternae are in close contact. Required for normal skeletal muscle strength. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats. | 0.504 |
Abra | Xirp1 | ENSMUSP00000051973 | ENSMUSP00000107262 | Actin-binding Rho-activating protein; Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling. | Xin actin-binding repeat-containing protein 1; Protects actin filaments from depolymerization. | 0.634 |
Ckmt2 | 2310002L09Rik | ENSMUSP00000022122 | ENSMUSP00000092633 | Creatine kinase S-type, mitochondrial; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa (By similarity). | RIKEN cDNA 2310002L09 gene. | 0.572 |
Ckmt2 | Abra | ENSMUSP00000022122 | ENSMUSP00000051973 | Creatine kinase S-type, mitochondrial; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa (By similarity). | Actin-binding Rho-activating protein; Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling. | 0.571 |
Ckmt2 | Itgb1bp2 | ENSMUSP00000022122 | ENSMUSP00000033674 | Creatine kinase S-type, mitochondrial; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa (By similarity). | Integrin beta-1-binding protein 2; May play a role during maturation and/or organization of muscles cells. | 0.615 |