node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bend5 | Bend6 | ENSMUSP00000030274 | ENSMUSP00000052919 | BEN domain-containing protein 5; Acts as a transcriptional repressor. | BEN domain-containing protein 6; Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis. | 0.673 |
Bend6 | Bend5 | ENSMUSP00000052919 | ENSMUSP00000030274 | BEN domain-containing protein 6; Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis. | BEN domain-containing protein 5; Acts as a transcriptional repressor. | 0.673 |
Bend6 | Bend7 | ENSMUSP00000052919 | ENSMUSP00000052458 | BEN domain-containing protein 6; Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis. | BEN domain-containing protein 7. | 0.725 |
Bend6 | Caskin2 | ENSMUSP00000052919 | ENSMUSP00000041328 | BEN domain-containing protein 6; Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis. | Caskin-2. | 0.452 |
Bend6 | Ccdc181 | ENSMUSP00000052919 | ENSMUSP00000027867 | BEN domain-containing protein 6; Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis. | Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids. | 0.432 |
Bend6 | L3mbtl1 | ENSMUSP00000052919 | ENSMUSP00000044038 | BEN domain-containing protein 6; Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis. | Lethal(3)malignant brain tumor-like protein 1; Polycomb group (PcG) protein that specifically recognizes and binds mono- and dimethyllysine residues on target proteins, therey acting as a 'reader' of a network of post-translational modifications. PcG proteins maintain the transcriptionally repressive state of genes: acts as a chromatin compaction factor by recognizing and binding mono- and dimethylated histone H1b/H1-4 at 'Lys-26' (H1bK26me1 and H1bK26me2) and histone H4 at 'Lys-20' (H4K20me1 and H4K20me2), leading to condense chromatin and repress transcription. Recognizes and binds p [...] | 0.499 |
Bend6 | Lrrc58 | ENSMUSP00000052919 | ENSMUSP00000077779 | BEN domain-containing protein 6; Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis. | Leucine-rich repeat-containing protein 58. | 0.582 |
Bend6 | Mettl27 | ENSMUSP00000052919 | ENSMUSP00000039080 | BEN domain-containing protein 6; Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis. | Williams-Beuren syndrome critical region protein 27 isoform alpha. | 0.441 |
Bend6 | Rbpj | ENSMUSP00000052919 | ENSMUSP00000040694 | BEN domain-containing protein 6; Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis. | Recombining binding protein suppressor of hairless; Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling [...] | 0.516 |
Bend6 | Sh2d5 | ENSMUSP00000052919 | ENSMUSP00000101449 | BEN domain-containing protein 6; Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis. | SH2 domain-containing protein 5; May be involved in synaptic plasticity regulation through the control of Rac-GTP levels. | 0.489 |
Bend6 | Zfp451 | ENSMUSP00000052919 | ENSMUSP00000019861 | BEN domain-containing protein 6; Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis. | E3 SUMO-protein ligase ZNF451; E3 SUMO-protein ligase; has a preference for SUMO2 and SUMO3 and facilitates UBE2I/UBC9-mediated sumoylation of target proteins. Plays a role in protein SUMO2 modification in response to stress caused by DNA damage and by proteasome inhibitors (in vitro). Required for MCM4 sumoylation. Has no activity with SUMO1. Preferentially transfers an additional SUMO2 chain onto the SUMO2 consensus site 'Lys-11'. Negatively regulates transcriptional activation mediated by the SMAD4 complex in response to TGF-beta signaling. Inhibits EP300-mediated acetylation of his [...] | 0.730 |
Bend7 | Bend6 | ENSMUSP00000052458 | ENSMUSP00000052919 | BEN domain-containing protein 7. | BEN domain-containing protein 6; Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis. | 0.725 |
Caskin2 | Bend6 | ENSMUSP00000041328 | ENSMUSP00000052919 | Caskin-2. | BEN domain-containing protein 6; Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis. | 0.452 |
Caskin2 | Lrrc58 | ENSMUSP00000041328 | ENSMUSP00000077779 | Caskin-2. | Leucine-rich repeat-containing protein 58. | 0.481 |
Caskin2 | Sh2d5 | ENSMUSP00000041328 | ENSMUSP00000101449 | Caskin-2. | SH2 domain-containing protein 5; May be involved in synaptic plasticity regulation through the control of Rac-GTP levels. | 0.402 |
Ccdc181 | Bend6 | ENSMUSP00000027867 | ENSMUSP00000052919 | Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids. | BEN domain-containing protein 6; Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis. | 0.432 |
L3mbtl1 | Bend6 | ENSMUSP00000044038 | ENSMUSP00000052919 | Lethal(3)malignant brain tumor-like protein 1; Polycomb group (PcG) protein that specifically recognizes and binds mono- and dimethyllysine residues on target proteins, therey acting as a 'reader' of a network of post-translational modifications. PcG proteins maintain the transcriptionally repressive state of genes: acts as a chromatin compaction factor by recognizing and binding mono- and dimethylated histone H1b/H1-4 at 'Lys-26' (H1bK26me1 and H1bK26me2) and histone H4 at 'Lys-20' (H4K20me1 and H4K20me2), leading to condense chromatin and repress transcription. Recognizes and binds p [...] | BEN domain-containing protein 6; Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis. | 0.499 |
Lrrc58 | Bend6 | ENSMUSP00000077779 | ENSMUSP00000052919 | Leucine-rich repeat-containing protein 58. | BEN domain-containing protein 6; Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis. | 0.582 |
Lrrc58 | Caskin2 | ENSMUSP00000077779 | ENSMUSP00000041328 | Leucine-rich repeat-containing protein 58. | Caskin-2. | 0.481 |
Mettl27 | Bend6 | ENSMUSP00000039080 | ENSMUSP00000052919 | Williams-Beuren syndrome critical region protein 27 isoform alpha. | BEN domain-containing protein 6; Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis. | 0.441 |