node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Atoh1 | Barhl1 | ENSMUSP00000098903 | ENSMUSP00000053147 | Protein atonal homolog 1; Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription. | BarH-like 1 homeobox protein; Belongs to the BAR homeobox family. | 0.765 |
Atoh1 | Lhx1 | ENSMUSP00000098903 | ENSMUSP00000018842 | Protein atonal homolog 1; Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription. | LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis. | 0.430 |
Atoh1 | Lhx2 | ENSMUSP00000098903 | ENSMUSP00000000253 | Protein atonal homolog 1; Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription. | LIM/homeobox protein Lhx2; Acts as a transcriptional activator. Stimulates the promoter of the alpha-glycoprotein gene. Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types. | 0.514 |
Atoh1 | Lhx5 | ENSMUSP00000098903 | ENSMUSP00000031591 | Protein atonal homolog 1; Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription. | LIM/homeobox protein Lhx5; Plays an essential role in the regulation of neuronal differentiation and migration during development of the central nervous system. | 0.455 |
Atoh1 | Lhx9 | ENSMUSP00000098903 | ENSMUSP00000107657 | Protein atonal homolog 1; Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription. | LIM/homeobox protein Lhx9; Involved in gonadal development. | 0.516 |
Atoh1 | Lmx1a | ENSMUSP00000098903 | ENSMUSP00000028003 | Protein atonal homolog 1; Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription. | LIM homeobox transcription factor 1-alpha; Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae. | 0.629 |
Atoh1 | Pou4f3 | ENSMUSP00000098903 | ENSMUSP00000025374 | Protein atonal homolog 1; Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription. | POU domain, class 4, transcription factor 3; Acts as a transcriptional activator. Acts by binding to sequences related to the consensus octamer motif 5'-ATGCAAAT-3' in the regulatory regions of its target genes. Involved in the auditory system development, required for terminal differentiation of hair cells in the inner ear ; Belongs to the POU transcription factor family. Class-4 subfamily. | 0.840 |
Atoh1 | Ptf1a | ENSMUSP00000098903 | ENSMUSP00000028068 | Protein atonal homolog 1; Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription. | Pancreas transcription factor 1 subunit alpha; Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5'-CANNTG-3'. Plays a role in early and late pancreas development and differentiation. Important for determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. May be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. Required for the formation of pancreatic acinar and ductal cells. Plays an impor [...] | 0.460 |
Atoh1 | Zic1 | ENSMUSP00000098903 | ENSMUSP00000034927 | Protein atonal homolog 1; Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription. | Zinc finger protein ZIC 1; Acts as a transcriptional activator. Involved in neurogenesis. Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cord development and maturation of the cerebellum. Involved in the spatial distribution of mossy fiber (MF) neurons within the pontine gray nucleus (PGN). Plays a role in the regulation of MF axon pathway choice. Promotes MF migration towards ipsilaterally-located cerebellar territories. May have a role in shear flow mechanotransduction in osteocytes. Retains nuclear GLI1 and GLI3 in the cytoplasm [...] | 0.506 |
Barhl1 | Atoh1 | ENSMUSP00000053147 | ENSMUSP00000098903 | BarH-like 1 homeobox protein; Belongs to the BAR homeobox family. | Protein atonal homolog 1; Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription. | 0.765 |
Barhl1 | Lhx1 | ENSMUSP00000053147 | ENSMUSP00000018842 | BarH-like 1 homeobox protein; Belongs to the BAR homeobox family. | LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis. | 0.527 |
Barhl1 | Lhx2 | ENSMUSP00000053147 | ENSMUSP00000000253 | BarH-like 1 homeobox protein; Belongs to the BAR homeobox family. | LIM/homeobox protein Lhx2; Acts as a transcriptional activator. Stimulates the promoter of the alpha-glycoprotein gene. Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types. | 0.485 |
Barhl1 | Lhx5 | ENSMUSP00000053147 | ENSMUSP00000031591 | BarH-like 1 homeobox protein; Belongs to the BAR homeobox family. | LIM/homeobox protein Lhx5; Plays an essential role in the regulation of neuronal differentiation and migration during development of the central nervous system. | 0.645 |
Barhl1 | Lhx9 | ENSMUSP00000053147 | ENSMUSP00000107657 | BarH-like 1 homeobox protein; Belongs to the BAR homeobox family. | LIM/homeobox protein Lhx9; Involved in gonadal development. | 0.559 |
Barhl1 | Lmx1a | ENSMUSP00000053147 | ENSMUSP00000028003 | BarH-like 1 homeobox protein; Belongs to the BAR homeobox family. | LIM homeobox transcription factor 1-alpha; Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae. | 0.551 |
Barhl1 | Nhlh1 | ENSMUSP00000053147 | ENSMUSP00000057489 | BarH-like 1 homeobox protein; Belongs to the BAR homeobox family. | Helix-loop-helix protein 1; May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system. | 0.481 |
Barhl1 | Pou4f3 | ENSMUSP00000053147 | ENSMUSP00000025374 | BarH-like 1 homeobox protein; Belongs to the BAR homeobox family. | POU domain, class 4, transcription factor 3; Acts as a transcriptional activator. Acts by binding to sequences related to the consensus octamer motif 5'-ATGCAAAT-3' in the regulatory regions of its target genes. Involved in the auditory system development, required for terminal differentiation of hair cells in the inner ear ; Belongs to the POU transcription factor family. Class-4 subfamily. | 0.676 |
Barhl1 | Ptf1a | ENSMUSP00000053147 | ENSMUSP00000028068 | BarH-like 1 homeobox protein; Belongs to the BAR homeobox family. | Pancreas transcription factor 1 subunit alpha; Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5'-CANNTG-3'. Plays a role in early and late pancreas development and differentiation. Important for determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. May be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. Required for the formation of pancreatic acinar and ductal cells. Plays an impor [...] | 0.624 |
Barhl1 | Zic1 | ENSMUSP00000053147 | ENSMUSP00000034927 | BarH-like 1 homeobox protein; Belongs to the BAR homeobox family. | Zinc finger protein ZIC 1; Acts as a transcriptional activator. Involved in neurogenesis. Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cord development and maturation of the cerebellum. Involved in the spatial distribution of mossy fiber (MF) neurons within the pontine gray nucleus (PGN). Plays a role in the regulation of MF axon pathway choice. Promotes MF migration towards ipsilaterally-located cerebellar territories. May have a role in shear flow mechanotransduction in osteocytes. Retains nuclear GLI1 and GLI3 in the cytoplasm [...] | 0.493 |
Lhx1 | Atoh1 | ENSMUSP00000018842 | ENSMUSP00000098903 | LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis. | Protein atonal homolog 1; Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription. | 0.430 |