node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Clec3a | Vat1l | ENSMUSP00000009018 | ENSMUSP00000053431 | C-type lectin domain family 3 member A; Promotes cell adhesion to laminin and fibronectin. | Synaptic vesicle membrane protein VAT-1 homolog-like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | 0.579 |
Clec3a | Wwox | ENSMUSP00000009018 | ENSMUSP00000004756 | C-type lectin domain family 3 member A; Promotes cell adhesion to laminin and fibronectin. | WW domain-containing oxidoreductase; Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm (By similarity). May also play a role in tumor necrosis factor (TNF)-mediated cell death. Required for normal bone development. | 0.480 |
Epm2aip1 | Vat1l | ENSMUSP00000052904 | ENSMUSP00000053431 | EPM2A-interacting protein 1. | Synaptic vesicle membrane protein VAT-1 homolog-like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | 0.462 |
Fasn | Vat1l | ENSMUSP00000052872 | ENSMUSP00000053431 | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein. | Synaptic vesicle membrane protein VAT-1 homolog-like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | 0.452 |
Gcnt4 | Vat1l | ENSMUSP00000130496 | ENSMUSP00000053431 | Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4; Glycosyltransferase that mediates core 2 O-glycan branching, an important step in mucin-type biosynthesis. Does not have core 4 O- glycan or I-branching enzyme activity. | Synaptic vesicle membrane protein VAT-1 homolog-like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | 0.468 |
Jakmip2 | Vat1l | ENSMUSP00000080881 | ENSMUSP00000053431 | Janus kinase and microtubule-interacting protein 2. | Synaptic vesicle membrane protein VAT-1 homolog-like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | 0.468 |
Krt23 | Vat1l | ENSMUSP00000006969 | ENSMUSP00000053431 | Keratin, type I cytoskeletal 23; Belongs to the intermediate filament family. | Synaptic vesicle membrane protein VAT-1 homolog-like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | 0.437 |
Strn4 | Vat1l | ENSMUSP00000019220 | ENSMUSP00000053431 | Striatin-4; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Belongs to the WD repeat striatin family. | Synaptic vesicle membrane protein VAT-1 homolog-like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | 0.444 |
Syce1l | Vat1l | ENSMUSP00000092796 | ENSMUSP00000053431 | Synaptonemal complex central element protein 1-like; May be involved in meiosis. Isoform 1 may be involved in meiosis during spermatogenesis while isoform 2 is probably related to a later stage of meiosis, in the development stage of secondary spermatocytes and spermatids; Belongs to the SYCE family. | Synaptic vesicle membrane protein VAT-1 homolog-like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | 0.503 |
Vat1l | Clec3a | ENSMUSP00000053431 | ENSMUSP00000009018 | Synaptic vesicle membrane protein VAT-1 homolog-like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | C-type lectin domain family 3 member A; Promotes cell adhesion to laminin and fibronectin. | 0.579 |
Vat1l | Epm2aip1 | ENSMUSP00000053431 | ENSMUSP00000052904 | Synaptic vesicle membrane protein VAT-1 homolog-like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | EPM2A-interacting protein 1. | 0.462 |
Vat1l | Fasn | ENSMUSP00000053431 | ENSMUSP00000052872 | Synaptic vesicle membrane protein VAT-1 homolog-like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein. | 0.452 |
Vat1l | Gcnt4 | ENSMUSP00000053431 | ENSMUSP00000130496 | Synaptic vesicle membrane protein VAT-1 homolog-like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4; Glycosyltransferase that mediates core 2 O-glycan branching, an important step in mucin-type biosynthesis. Does not have core 4 O- glycan or I-branching enzyme activity. | 0.468 |
Vat1l | Jakmip2 | ENSMUSP00000053431 | ENSMUSP00000080881 | Synaptic vesicle membrane protein VAT-1 homolog-like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | Janus kinase and microtubule-interacting protein 2. | 0.468 |
Vat1l | Krt23 | ENSMUSP00000053431 | ENSMUSP00000006969 | Synaptic vesicle membrane protein VAT-1 homolog-like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | Keratin, type I cytoskeletal 23; Belongs to the intermediate filament family. | 0.437 |
Vat1l | Strn4 | ENSMUSP00000053431 | ENSMUSP00000019220 | Synaptic vesicle membrane protein VAT-1 homolog-like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | Striatin-4; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Belongs to the WD repeat striatin family. | 0.444 |
Vat1l | Syce1l | ENSMUSP00000053431 | ENSMUSP00000092796 | Synaptic vesicle membrane protein VAT-1 homolog-like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | Synaptonemal complex central element protein 1-like; May be involved in meiosis. Isoform 1 may be involved in meiosis during spermatogenesis while isoform 2 is probably related to a later stage of meiosis, in the development stage of secondary spermatocytes and spermatids; Belongs to the SYCE family. | 0.503 |
Vat1l | Wdr18 | ENSMUSP00000053431 | ENSMUSP00000041049 | Synaptic vesicle membrane protein VAT-1 homolog-like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | WD repeat-containing protein 18; May play a role during development (By similarity). Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes; Belongs to the WD repeat IPI3/WDR18 family. | 0.473 |
Vat1l | Wwox | ENSMUSP00000053431 | ENSMUSP00000004756 | Synaptic vesicle membrane protein VAT-1 homolog-like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | WW domain-containing oxidoreductase; Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm (By similarity). May also play a role in tumor necrosis factor (TNF)-mediated cell death. Required for normal bone development. | 0.495 |
Wdr18 | Vat1l | ENSMUSP00000041049 | ENSMUSP00000053431 | WD repeat-containing protein 18; May play a role during development (By similarity). Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes; Belongs to the WD repeat IPI3/WDR18 family. | Synaptic vesicle membrane protein VAT-1 homolog-like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | 0.473 |