node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ankrd13d | Fam220a | ENSMUSP00000053783 | ENSMUSP00000126480 | Ankyrin repeat domain-containing protein 13D; Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane (By similarity). | Protein FAM220A; May negatively regulate STAT3. | 0.547 |
Ankrd13d | Fam220a-2 | ENSMUSP00000053783 | ENSMUSP00000143202 | Ankyrin repeat domain-containing protein 13D; Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane (By similarity). | Family with sequence similarity 220, member A. | 0.661 |
Ankrd13d | Fam222a | ENSMUSP00000053783 | ENSMUSP00000045724 | Ankyrin repeat domain-containing protein 13D; Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane (By similarity). | Protein FAM222A; Belongs to the FAM222 family. | 0.701 |
Ankrd13d | Gm11808 | ENSMUSP00000053783 | ENSMUSP00000086852 | Ankyrin repeat domain-containing protein 13D; Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane (By similarity). | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] | 0.578 |
Ankrd13d | Gm8797 | ENSMUSP00000053783 | ENSMUSP00000141419 | Ankyrin repeat domain-containing protein 13D; Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane (By similarity). | Predicted pseudogene 8797. | 0.548 |
Ankrd13d | Lrrc73 | ENSMUSP00000053783 | ENSMUSP00000156533 | Ankyrin repeat domain-containing protein 13D; Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane (By similarity). | Leucine-rich repeat-containing 73. | 0.542 |
Ankrd13d | Nprl2 | ENSMUSP00000053783 | ENSMUSP00000010201 | Ankyrin repeat domain-containing protein 13D; Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane (By similarity). | GATOR complex protein NPRL2; As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway; Belongs to the NPR2 family. | 0.525 |
Ankrd13d | Tbccd1 | ENSMUSP00000053783 | ENSMUSP00000004576 | Ankyrin repeat domain-containing protein 13D; Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane (By similarity). | TBCC domain-containing protein 1; Plays a role in the regulation of centrosome and Golgi apparatus positioning, with consequences on cell shape and cell migration; Belongs to the TBCC family. | 0.644 |
Ankrd13d | Tepsin | ENSMUSP00000053783 | ENSMUSP00000091428 | Ankyrin repeat domain-containing protein 13D; Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane (By similarity). | AP-4 complex accessory subunit Tepsin; Associates with the adapter-like complex 4 (AP-4) and may therefore play a role in vesicular trafficking of proteins at the trans-Golgi network. | 0.521 |
Ankrd13d | Uba52 | ENSMUSP00000053783 | ENSMUSP00000120096 | Ankyrin repeat domain-containing protein 13D; Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane (By similarity). | Ubiquitin A-52 residue ribosomal protein fusion product 1. | 0.578 |
Fam220a | Ankrd13d | ENSMUSP00000126480 | ENSMUSP00000053783 | Protein FAM220A; May negatively regulate STAT3. | Ankyrin repeat domain-containing protein 13D; Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane (By similarity). | 0.547 |
Fam220a | Fam222a | ENSMUSP00000126480 | ENSMUSP00000045724 | Protein FAM220A; May negatively regulate STAT3. | Protein FAM222A; Belongs to the FAM222 family. | 0.503 |
Fam220a | Tbccd1 | ENSMUSP00000126480 | ENSMUSP00000004576 | Protein FAM220A; May negatively regulate STAT3. | TBCC domain-containing protein 1; Plays a role in the regulation of centrosome and Golgi apparatus positioning, with consequences on cell shape and cell migration; Belongs to the TBCC family. | 0.480 |
Fam220a-2 | Ankrd13d | ENSMUSP00000143202 | ENSMUSP00000053783 | Family with sequence similarity 220, member A. | Ankyrin repeat domain-containing protein 13D; Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane (By similarity). | 0.661 |
Fam220a-2 | Fam222a | ENSMUSP00000143202 | ENSMUSP00000045724 | Family with sequence similarity 220, member A. | Protein FAM222A; Belongs to the FAM222 family. | 0.632 |
Fam220a-2 | Tbccd1 | ENSMUSP00000143202 | ENSMUSP00000004576 | Family with sequence similarity 220, member A. | TBCC domain-containing protein 1; Plays a role in the regulation of centrosome and Golgi apparatus positioning, with consequences on cell shape and cell migration; Belongs to the TBCC family. | 0.596 |
Fam222a | Ankrd13d | ENSMUSP00000045724 | ENSMUSP00000053783 | Protein FAM222A; Belongs to the FAM222 family. | Ankyrin repeat domain-containing protein 13D; Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane (By similarity). | 0.701 |
Fam222a | Fam220a | ENSMUSP00000045724 | ENSMUSP00000126480 | Protein FAM222A; Belongs to the FAM222 family. | Protein FAM220A; May negatively regulate STAT3. | 0.503 |
Fam222a | Fam220a-2 | ENSMUSP00000045724 | ENSMUSP00000143202 | Protein FAM222A; Belongs to the FAM222 family. | Family with sequence similarity 220, member A. | 0.632 |
Fam222a | Tbccd1 | ENSMUSP00000045724 | ENSMUSP00000004576 | Protein FAM222A; Belongs to the FAM222 family. | TBCC domain-containing protein 1; Plays a role in the regulation of centrosome and Golgi apparatus positioning, with consequences on cell shape and cell migration; Belongs to the TBCC family. | 0.659 |