node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Krt16 | Krt6a | ENSMUSP00000007280 | ENSMUSP00000023788 | Keratin, type I cytoskeletal 16; Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance. | Keratin, type II cytoskeletal 6A; Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair. Belongs to the intermediate filament family. | 0.893 |
Krt16 | Lce1m | ENSMUSP00000007280 | ENSMUSP00000029520 | Keratin, type I cytoskeletal 16; Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance. | Late cornified envelope 1M. | 0.508 |
Krt16 | Rptn | ENSMUSP00000007280 | ENSMUSP00000044998 | Keratin, type I cytoskeletal 16; Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance. | Repetin; Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein; Belongs to the S100-fused protein family. | 0.412 |
Krt16 | Sprr1b | ENSMUSP00000007280 | ENSMUSP00000058617 | Keratin, type I cytoskeletal 16; Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance. | Cornifin-B; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane; Belongs to the cornifin (SPRR) family. | 0.667 |
Krt16 | Sprr2d | ENSMUSP00000007280 | ENSMUSP00000039821 | Keratin, type I cytoskeletal 16; Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance. | Small proline-rich protein 2D; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity). | 0.626 |
Krt16 | Sprr2h | ENSMUSP00000007280 | ENSMUSP00000053849 | Keratin, type I cytoskeletal 16; Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance. | Small proline-rich protein 2H; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity); Belongs to the cornifin (SPRR) family. | 0.584 |
Krt6a | Krt16 | ENSMUSP00000023788 | ENSMUSP00000007280 | Keratin, type II cytoskeletal 6A; Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair. Belongs to the intermediate filament family. | Keratin, type I cytoskeletal 16; Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance. | 0.893 |
Krt6a | Rptn | ENSMUSP00000023788 | ENSMUSP00000044998 | Keratin, type II cytoskeletal 6A; Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair. Belongs to the intermediate filament family. | Repetin; Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein; Belongs to the S100-fused protein family. | 0.503 |
Krt6a | Sprr1b | ENSMUSP00000023788 | ENSMUSP00000058617 | Keratin, type II cytoskeletal 6A; Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair. Belongs to the intermediate filament family. | Cornifin-B; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane; Belongs to the cornifin (SPRR) family. | 0.578 |
Krt6a | Sprr2d | ENSMUSP00000023788 | ENSMUSP00000039821 | Keratin, type II cytoskeletal 6A; Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair. Belongs to the intermediate filament family. | Small proline-rich protein 2D; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity). | 0.630 |
Krt6a | Sprr2h | ENSMUSP00000023788 | ENSMUSP00000053849 | Keratin, type II cytoskeletal 6A; Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair. Belongs to the intermediate filament family. | Small proline-rich protein 2H; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity); Belongs to the cornifin (SPRR) family. | 0.601 |
Lce1g | Lce1h | ENSMUSP00000029527 | ENSMUSP00000058647 | Late cornified envelope 1G. | Late cornified envelope 1H. | 0.588 |
Lce1g | Lce1m | ENSMUSP00000029527 | ENSMUSP00000029520 | Late cornified envelope 1G. | Late cornified envelope 1M. | 0.792 |
Lce1g | Rptn | ENSMUSP00000029527 | ENSMUSP00000044998 | Late cornified envelope 1G. | Repetin; Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein; Belongs to the S100-fused protein family. | 0.592 |
Lce1g | Sprr1b | ENSMUSP00000029527 | ENSMUSP00000058617 | Late cornified envelope 1G. | Cornifin-B; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane; Belongs to the cornifin (SPRR) family. | 0.478 |
Lce1g | Sprr2h | ENSMUSP00000029527 | ENSMUSP00000053849 | Late cornified envelope 1G. | Small proline-rich protein 2H; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity); Belongs to the cornifin (SPRR) family. | 0.637 |
Lce1h | Lce1g | ENSMUSP00000058647 | ENSMUSP00000029527 | Late cornified envelope 1H. | Late cornified envelope 1G. | 0.588 |
Lce1h | Lce1m | ENSMUSP00000058647 | ENSMUSP00000029520 | Late cornified envelope 1H. | Late cornified envelope 1M. | 0.764 |
Lce1h | Rptn | ENSMUSP00000058647 | ENSMUSP00000044998 | Late cornified envelope 1H. | Repetin; Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein; Belongs to the S100-fused protein family. | 0.525 |
Lce1h | Sprr2d | ENSMUSP00000058647 | ENSMUSP00000039821 | Late cornified envelope 1H. | Small proline-rich protein 2D; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity). | 0.500 |