node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dvl1 | Rassf9 | ENSMUSP00000030948 | ENSMUSP00000151843 | Segment polarity protein dishevelled homolog DVL-1; Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ). Belongs [...] | Ras association domain-containing protein 9; May play a role in regulating vesicuar trafficking in cells. | 0.471 |
Mmrn1 | Rassf9 | ENSMUSP00000119609 | ENSMUSP00000151843 | Multimerin-1; Carrier protein for platelet (but not plasma) factor V/Va. Plays a role in the storage and stabilization of factor V in platelets. Upon release following platelet activation, may limit platelet and plasma factor Va-dependent thrombin generation. Ligand for integrin alpha-IIb/beta-3 and integrin alpha-V/beta-3 on activated platelets, and may function as an extracellular matrix or adhesive protein (By similarity). | Ras association domain-containing protein 9; May play a role in regulating vesicuar trafficking in cells. | 0.481 |
Mtmr10 | Pex11g | ENSMUSP00000032736 | ENSMUSP00000004686 | Myotubularin-related protein 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | Peroxisomal membrane protein 11C; Promotes membrane protrusion and elongation on the peroxisomal surface. | 0.452 |
Mtmr10 | Pqlc3 | ENSMUSP00000032736 | ENSMUSP00000054462 | Myotubularin-related protein 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | Solute carrier family 66 member 3. | 0.454 |
Mtmr10 | Rassf9 | ENSMUSP00000032736 | ENSMUSP00000151843 | Myotubularin-related protein 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | Ras association domain-containing protein 9; May play a role in regulating vesicuar trafficking in cells. | 0.512 |
Mtmr10 | Rsbn1 | ENSMUSP00000032736 | ENSMUSP00000069246 | Myotubularin-related protein 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | Lysine-specific demethylase 9; Histone demethylase that specifically demethylates dimethylated 'Lys-20' of histone H4 (H4K20me2), thereby modulating chromosome architecture; Belongs to the round spermatid basic protein 1 family. | 0.451 |
Olfr1396 | Rassf9 | ENSMUSP00000150961 | ENSMUSP00000151843 | Olfactory receptor. | Ras association domain-containing protein 9; May play a role in regulating vesicuar trafficking in cells. | 0.475 |
Pam | Rassf9 | ENSMUSP00000095228 | ENSMUSP00000151843 | Peptidyl-alpha-hydroxyglycine alpha-amidating lyase; Bifunctional enzyme that catalyzes the post-translational modification of inactive peptidylglycine precursors to the corresponding bioactive alpha-amidated peptides, a terminal modification in biosynthesis of many neural and endocrine peptides (By similarity). Alpha-amidation involves two sequential reactions, both of which are catalyzed by separate catalytic domains of the enzyme. The first step, catalyzed by peptidyl alpha-hydroxylating monoxygenase (PHM) domain, is the copper-, ascorbate-, and O2- dependent stereospecific hydroxyl [...] | Ras association domain-containing protein 9; May play a role in regulating vesicuar trafficking in cells. | 0.668 |
Pex11g | Mtmr10 | ENSMUSP00000004686 | ENSMUSP00000032736 | Peroxisomal membrane protein 11C; Promotes membrane protrusion and elongation on the peroxisomal surface. | Myotubularin-related protein 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | 0.452 |
Pex11g | Pqlc3 | ENSMUSP00000004686 | ENSMUSP00000054462 | Peroxisomal membrane protein 11C; Promotes membrane protrusion and elongation on the peroxisomal surface. | Solute carrier family 66 member 3. | 0.450 |
Pex11g | Rassf9 | ENSMUSP00000004686 | ENSMUSP00000151843 | Peroxisomal membrane protein 11C; Promotes membrane protrusion and elongation on the peroxisomal surface. | Ras association domain-containing protein 9; May play a role in regulating vesicuar trafficking in cells. | 0.435 |
Pex11g | Rsbn1 | ENSMUSP00000004686 | ENSMUSP00000069246 | Peroxisomal membrane protein 11C; Promotes membrane protrusion and elongation on the peroxisomal surface. | Lysine-specific demethylase 9; Histone demethylase that specifically demethylates dimethylated 'Lys-20' of histone H4 (H4K20me2), thereby modulating chromosome architecture; Belongs to the round spermatid basic protein 1 family. | 0.498 |
Pqlc3 | Mtmr10 | ENSMUSP00000054462 | ENSMUSP00000032736 | Solute carrier family 66 member 3. | Myotubularin-related protein 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | 0.454 |
Pqlc3 | Pex11g | ENSMUSP00000054462 | ENSMUSP00000004686 | Solute carrier family 66 member 3. | Peroxisomal membrane protein 11C; Promotes membrane protrusion and elongation on the peroxisomal surface. | 0.450 |
Pqlc3 | Rassf9 | ENSMUSP00000054462 | ENSMUSP00000151843 | Solute carrier family 66 member 3. | Ras association domain-containing protein 9; May play a role in regulating vesicuar trafficking in cells. | 0.428 |
Pqlc3 | Rsbn1 | ENSMUSP00000054462 | ENSMUSP00000069246 | Solute carrier family 66 member 3. | Lysine-specific demethylase 9; Histone demethylase that specifically demethylates dimethylated 'Lys-20' of histone H4 (H4K20me2), thereby modulating chromosome architecture; Belongs to the round spermatid basic protein 1 family. | 0.407 |
Rassf6 | Rassf7 | ENSMUSP00000031317 | ENSMUSP00000038444 | Ras association domain-containing protein 6; Involved in the induction of apoptosis. May act as a Ras effector protein. May suppress the serum-induced basal levels of NF- kappa-B. | Ras association domain-containing protein 7; Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization (By similarity). | 0.833 |
Rassf6 | Rassf9 | ENSMUSP00000031317 | ENSMUSP00000151843 | Ras association domain-containing protein 6; Involved in the induction of apoptosis. May act as a Ras effector protein. May suppress the serum-induced basal levels of NF- kappa-B. | Ras association domain-containing protein 9; May play a role in regulating vesicuar trafficking in cells. | 0.447 |
Rassf7 | Rassf6 | ENSMUSP00000038444 | ENSMUSP00000031317 | Ras association domain-containing protein 7; Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization (By similarity). | Ras association domain-containing protein 6; Involved in the induction of apoptosis. May act as a Ras effector protein. May suppress the serum-induced basal levels of NF- kappa-B. | 0.833 |
Rassf7 | Rassf9 | ENSMUSP00000038444 | ENSMUSP00000151843 | Ras association domain-containing protein 7; Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization (By similarity). | Ras association domain-containing protein 9; May play a role in regulating vesicuar trafficking in cells. | 0.718 |